Search Results - "Araúzo‐Bravo, Marcos J."
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Induction of Pluripotency in Adult Unipotent Germline Stem Cells
Published in Cell stem cell (02-07-2009)“…Mouse and human stem cells with features similar to those of embryonic stem cells have been derived from testicular cells. Although pluripotent stem cells have…”
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Reprogramming of two somatic nuclei in the same ooplasm leads to pluripotent embryonic stem cells
Published in Stem cells (Dayton, Ohio) (01-11-2013)“…The conversion of the nuclear program of a somatic cell from a differentiated to an undifferentiated state can be accomplished by transplanting its nucleus to…”
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Conversion of adult mouse unipotent germline stem cells into pluripotent stem cells
Published in Nature protocols (01-05-2010)“…Germline stem cells (GSCs), often called spermatogonial stem cells, are unipotent stem cells that can give rise only to gametes. Under defined culture…”
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Effect of cra gene knockout together with edd and iclR genes knockout on the metabolism in Escherichia coli
Published in Archives of microbiology (01-11-2008)“…To elucidate the physiological adaptation of Escherichia coli due to cra gene knockout, a total of 3,911 gene expressions were investigated by DNA microarray…”
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Generation of Parthenogenetic Induced Pluripotent Stem Cells from Parthenogenetic Neural Stem Cells
Published in Stem cells (Dayton, Ohio) (01-12-2009)“…Somatic cells can achieve a pluripotent cell state in a process called pluripotential reprogramming. Multipotent stem cells can differentiate into cells of…”
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Sequence-Dependent Conformational Energy of DNA Derived from Molecular Dynamics Simulations: Toward Understanding the Indirect Readout Mechanism in Protein−DNA Recognition
Published in Journal of the American Chemical Society (23-11-2005)“…Sequence dependence of DNA conformation plays a crucial role in its recognition by proteins and ligands. To clarify the relationship between sequence and…”
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Cell-to-cell expression variability followed by signal reinforcement progressively segregates early mouse lineages
Published in Nature cell biology (01-01-2014)“…It is now recognized that extensive expression heterogeneities among cells precede the emergence of lineages in the early mammalian embryo. To establish a map…”
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Direct reprogramming of human neural stem cells by OCT4
Published in Nature (London) (01-10-2009)“…Induced pluripotent stem (iPS) cells have been generated from mouse and human somatic cells by ectopic expression of four transcription factors (OCT4 (also…”
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Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes In Vivo Attenuates Liver Fibrosis
Published in Cell stem cell (02-06-2016)“…Direct induction of induced hepatocytes (iHeps) from fibroblasts holds potential as a strategy for regenerative medicine but until now has only been shown in…”
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Direct Reprogramming of Fibroblasts into Neural Stem Cells by Defined Factors
Published in Cell stem cell (06-04-2012)“…Recent studies have shown that defined sets of transcription factors can directly reprogram differentiated somatic cells to a different differentiated cell…”
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Skeletal Muscles of Sedentary and Physically Active Aged People Have Distinctive Genic Extrachromosomal Circular DNA Profiles
Published in International journal of molecular sciences (01-02-2023)“…To bring new extrachromosomal circular DNA (eccDNA) enrichment technologies closer to the clinic, specifically for screening, early diagnosis, and monitoring…”
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Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile
Published in The EMBO journal (15-04-2015)“…Primordial germ cells (PGCs) develop only into sperm and oocytes in vivo . The molecular mechanisms underlying human PGC specification are poorly understood…”
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Indirect readout in drug-DNA recognition: role of sequence-dependent DNA conformation
Published in Nucleic acids research (01-02-2008)“…DNA-binding drugs have numerous applications in the engineered gene regulation. However, the drug-DNA recognition mechanism is poorly understood. Drugs can…”
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Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis
Published in Nature (London) (10-01-2013)“…Adult neural stem and progenitor cells (NSPCs) show high levels of fatty acid synthase (Fasn)-dependent de novo lipogenesis, a process that is controlled by…”
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RNA-sequencing from single nuclei
Published in Proceedings of the National Academy of Sciences - PNAS (03-12-2013)“…It has recently been established that synthesis of double-stranded cDNA can be done from a single cell for use in DNA sequencing. Global gene expression can be…”
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DNA methylation regulates discrimination of enhancers from promoters through a H3K4me1-H3K4me3 seesaw mechanism
Published in BMC genomics (12-12-2017)“…DNA methylation at promoters is largely correlated with inhibition of gene expression. However, the role of DNA methylation at enhancers is not fully…”
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Revised roles of ISL1 in a hES cell-based model of human heart chamber specification
Published in eLife (16-01-2018)“…The transcription factor ISL1 is thought to be key for conveying the multipotent and proliferative properties of cardiac precursor cells. Here, we investigate…”
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Targeting liver sinusoidal endothelial cells with miR‐20a‐loaded nanoparticles reduces murine colon cancer metastasis to the liver
Published in International journal of cancer (01-08-2018)“…Phenotypic transformation of liver sinusoidal endothelial cells is one of the most important stages of liver metastasis progression. The miRNA effects on liver…”
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The K2P‐channel TASK1 affects Oligodendroglial differentiation but not myelin restoration
Published in Glia (01-05-2019)“…In multiple sclerosis, demyelination occurs as a consequence of chronic autoimmunity in the central nervous system causing progressive neurological impairment…”
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Direct Induction of Trophoblast Stem Cells from Murine Fibroblasts
Published in Cell stem cell (05-11-2015)“…Trophoblast stem cells (TSCs) arise from the first cell fate decision in the developing embryo and generate extra-embryonic lineages, giving rise to the fetal…”
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