Search Results - "Araújo Silva, Cleide Lúcia"
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Mast cell-T cell axis alters development of colitis-dependent and colitis-independent colorectal tumours: potential for therapeutically targeting via mast cell inhibition
Published in Journal for immunotherapy of cancer (01-10-2022)“…BackgroundColorectal cancer (CRC) has a high mortality rate and can develop in either colitis-dependent (colitis-associated (CA)-CRC) or colitis-independent…”
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2
CCR2 Plays a Protective Role in Rocio Virus-Induced Encephalitis by Promoting Macrophage Infiltration Into the Brain
Published in The Journal of infectious diseases (24-05-2019)“…Rocio virus (ROCV) is a highly neuropathogenic mosquito-transmitted flavivirus responsible for an unprecedented outbreak of human encephalitis during 1975-1976…”
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Influence of a Physiologically Formed Blood Clot on Pre-Osteoblastic Cells Grown on a BMP-7-Coated Nanoporous Titanium Surface
Published in Biomimetics (Basel, Switzerland) (01-03-2023)“…Titanium (Ti) nanotopography modulates the osteogenic response to exogenous bone morphogenetic protein 7 (BMP-7) in vitro, supporting enhanced alkaline…”
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Panobinostat (LBH589) increase survival in adult xenografic model of acute lymphoblastic leukemia with t(4;11) but promotes antagonistic effects in combination with MTX and 6MP
Published in Medical oncology (Northwood, London, England) (29-09-2022)“…Patients diagnosed with acute lymphoblastic leukemia (ALL) bearing t(4;11)/MLL-AF4 have aggressive clinical features, poor prognosis and there is an urgent…”
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The lipid raft protein NTAL participates in AKT signaling in mantle cell lymphoma
Published in Leukemia & lymphoma (19-09-2019)“…Lipid rafts are ordered membrane domains, which provide an environment for the proteins participating in signal transduction. Perifosine is an…”
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NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia
Published in Scientific reports (25-06-2020)“…Non-T cell activation linker (NTAL) is a lipid raft-membrane protein expressed by normal and leukemic cells and involved in cell signaling. In acute…”
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Reactive oxygen species production triggers green tea-induced anti-leukaemic effects on acute promyelocytic leukaemia model
Published in Cancer letters (01-02-2018)“…Green tea (GT) has been consumed as a beverage for thousands of years because of its therapeutic properties observed over time. Because there is no sufficient…”
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Jak2V617F Bone Marrow Exposure Leads to Dysfunction of Normal NK Cells
Published in Blood (02-11-2023)“…Introduction: We have previously demonstrated a functional impairment of NK cells in the Jak2V617F murine model and peripheral blood cells from patients with…”
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Irs1S57X Heterozygous Mutant Mice Display Normal Hematopoiesis and Phenotypic Features, While Homozygous Knockout Exhibit High Fetal or Postnatal Lethality
Published in Blood (05-11-2020)“…Introduction: Pharmacological inhibition of insulin receptor substrate 1 (IRS1) protein has been demonstrated to promote antineoplastic effects in…”
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Abstract B33: Synergistic effect of gefitinib and arsenic trioxide in acute promyelocytic leukemia
Published in Clinical cancer research (01-01-2018)“…Gefitinib and erlotinib are well-known epidermal growth factor receptor (EGFR) inhibitors approved by the Food and Drug Administration for the treatment of…”
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Halofuginone Exerts Antileukemic Effects in TP53 Mutated Cell Lines
Published in Blood (08-12-2017)“…Introduction: The application of the standardized therapy based on anthracyclines and cytarabine for all patients with AML regardless of which molecular…”
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