Search Results - "Araújo, Glaucy Rodrigues"
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Nrf2 cell signaling pathway is responsible for the antioxidant effect of resveratrol in aging
Published in Geriatrics & gerontology international (01-09-2024)“…Introduction One of the markers of aging is oxidative stress, a condition characterized by an increase in free radicals concomitant with a reduction in…”
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The preventive use of resveratrol increases its antioxidant effect by SIRT1 and subclinical anti-inflammatory action in Neuro-2A cells
Published in In vitro cellular & developmental biology. Animal (01-12-2022)“…Currently, the important role of oxidative stress in the aging process and in neurodegenerative diseases has been highlighted, suggesting the beneficial effect…”
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Antioxidant effect of Resveratrol: Change in MAPK cell signaling pathway during the aging process
Published in Archives of gerontology and geriatrics (01-01-2021)“…•Resveratrol is a polyphenol with potent antioxidant effect.•Elderly individuals have higher baseline oxidative stress.•Resveratrol has better antioxidant…”
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Resveratrol: Change of SIRT 1 and AMPK signaling pattern during the aging process
Published in Experimental gerontology (01-04-2021)“…One of the causes for aging is free radical damage. Resveratrol (RSV), a polyphenolic compound has been shown to act as an antioxidant and anti-inflammatory…”
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Resveratrol has its antioxidant and anti-inflammatory protective mechanisms decreased in aging
Published in Archives of gerontology and geriatrics (01-04-2023)“…•One of the hallmarks of aging is increased oxidative stress and chronic inflammation.•In aging, there is an increase in TNF and Interleukin-6.•Resveratrol is…”
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The antioxidant and anti-inflammatory properties of lycopene in mice lungs exposed to cigarette smoke
Published in The Journal of nutritional biochemistry (01-10-2017)“…Lycopene is a carotenoid with known antioxidant and anti-inflammatory properties. We aimed to evaluate the in vitro and in vivo effects of lycopene on reducing…”
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Aging: silencing the PKA and AkT/PKB signaling pathways alters the antioxidant capacity of resveratrol
Published in Biogerontology (Dordrecht) (01-12-2023)“…One of the theories related to aging is the increase in oxidative stress. Given this, the objective of the study is to evaluate the cellular mechanisms…”
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Baccharis trimera protects against ethanol induced hepatotoxicity in vitro and in vivo
Published in Journal of ethnopharmacology (06-04-2018)“…Baccharis trimera has been traditionally used in Brazil to treat liver diseases. To evaluate the protective effect of Baccharis trimera in an ethanol induced…”
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Vildagliptin Ameliorates Oxidative Stress and Pancreatic Beta Cell Destruction in Type 1 Diabetic Rats
Published in Archives of medical research (01-04-2013)“…Background and Aims It is believed that oxidative stress plays a role in the pathogenesis of diabetes mellitus. Several strategies have been developed with the…”
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Annatto extract and β-carotene enhances antioxidant status and regulate gene expression in neutrophils of diabetic rats
Published in Free radical research (01-03-2012)“…Annatto (Bixa orellana L.) contains a mixture of orange-yellowish pigments due to the presence of various carotenoids that have antioxidant effect. The immune…”
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Annato extract and β-carotene modulate the production of reactive oxygen species/nitric oxide in neutrophils from diabetic rats
Published in Journal of Clinical Biochemistry and Nutrition (01-05-2012)“…Annatto has been identified as carotenoids that have antioxidative effects. It is well known that one of the key elements in the development of diabetic…”
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Silencing of the Nrf2 pathway in aging promotes a decrease in the anti-inflammatory effect of resveratrol
Published in Archives of gerontology and geriatrics (01-02-2025)“…•Aging is related to oxidative stress and inflammation.•Resveratrol, through Nrf2, appears to act in the increase of IL-10.•The Nrf2 cell signaling pathway is…”
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Early calcium handling imbalance in pressure overload-induced heart failure with nearly normal left ventricular ejection fraction
Published in Biochimica et biophysica acta. Molecular basis of disease (01-01-2019)“…Heart failure with preserved ejection fraction (HFpEF) is a common clinical syndrome associated with high morbidity and mortality. Therapeutic options are…”
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Right coronary artery ligation in mice: a novel method to investigate right ventricular dysfunction and biventricular interaction
Published in American journal of physiology. Heart and circulatory physiology (01-03-2019)“…Right ventricular (RV) dysfunction can lead to complications after acute inferior myocardial infarction (MI). However, it is unclear how RV failure after MI…”
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Baccharis trimera (Carqueja) Improves Metabolic and Redox Status in an Experimental Model of Type 1 Diabetes
Published in Evidence-based complementary and alternative medicine (01-01-2018)“…Diabetes mellitus is a metabolic disorder that causes severe complications due to the increased oxidative stress induced by disease. Many plants are popularly…”
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Baccharis trimera inhibits reactive oxygen species production through PKC and down-regulation p47 phox phosphorylation of NADPH oxidase in SK Hep-1 cells
Published in Experimental biology and medicine (Maywood, N.J.) (01-02-2017)“…Baccharis trimera, popularly known as “carqueja”, is a native South-American plant possessing a high concentration of polyphenolic compounds and therefore high…”
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Baccharis trimera inhibits reactive oxygen species production through PKC and down-regulation p47phox phosphorylation of NADPH oxidase in SK Hep-1 cells
Published in Experimental biology and medicine (Maywood, N.J.) (07-10-2016)“…Baccharis trimera , popularly known as “carqueja”, is a native South-American plant possessing a high concentration of polyphenolic compounds and therefore…”
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Effect of captopril and the bradykinin-PKC pathway on ROS production in type 1 diabetic rats
Published in Canadian journal of physiology and pharmacology (01-12-2011)“…The aim of this study was to investigate the possible effects of captopril as a promoter in modulating the oxidant-antioxidant balance in rats with type 1…”
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Annato extract and [beta]-carotene modulate the production of reactive oxygen species/nitric oxide in neutrophils from diabetic rats
Published in Journal of clinical biochemistry and nutrition (01-05-2012)“…Annatto has been identified as carotenoids that have antioxidative effects. It is well known that one of the key elements in the development of diabetic…”
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Lycopene inhibits reactive oxygen species production in SK-Hep-1 cells and attenuates acetaminophen-induced liver injury in C57BL/6 mice
Published in Chemico-biological interactions (01-02-2017)“…Our aim was to investigate the antioxidant potential of lycopene in different experimental liver models: in vitro, to evaluate the influence of lycopene on…”
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