Search Results - "Arányi, P"
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Past and future of an IMI-PharmaTrain (IMI-PhT)-initiated multinational pharmaceutical medicine course at the Semmelweis University in Hungary
Published in Frontiers in pharmacology (30-04-2024)“…The pharmaceutical medicine course at the Semmelweis University of Budapest, Hungary, was initiated as part of the Innovative Medicines Initiative (IMI is the…”
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Postconditioning attenuates remote organ injury after lower limb arterial occlusion
Published in Interventional medicine and applied science (01-12-2010)Get full text
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A new potent calmodulin antagonist with arylalkylamine structure: crystallographic, spectroscopic and functional studies
Published in Journal of molecular biology (31-03-2000)“…An arylalkylamine-type calmodulin antagonist, N-(3,3-diphenylpropyl)- N′-[1-R-(3,4-bis-butoxyphenyl)ethyl]-propylene-diamine (AAA) is presented and its…”
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Different neurorescue profiles of selegiline and p-fluoro-selegiline in gerbils
Published in Neuroreport (03-08-2000)“…The neuroprotective/neuronal rescue effects of selegiline are not exactly understood, and show great variability in clinical trials. In this study, the…”
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Measurement and drug induced modulation of interleukin-1 level during zymosan peritonitis in mice
Published in Inflammation research (01-06-1995)“…The time-course and pharmacological modulation of interleukin-1 (IL-1) production were investigated during zymosan induced peritonitis in mice. IL-1 alpha…”
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Kinetics of the hormone-receptor interaction. Competition experiments with slowly equilibrating ligands
Published in Biochimica et biophysica acta (01-01-1980)“…Kinetics of formation of protein-tracer complex in the presence of competitor were calculated. The parameters were chosen so that they should realistically…”
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Effect of heparin on thrombin inactivation by antithrombin-III
Published in Biochemical journal (01-09-1978)“…The inactivation of thrombin by heat and by its physiological inhibitor, antithrombin-III, shows quite different dependence on heparin concentration. Heparin…”
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Effect of cross-linking on glucocorticoid receptor activation
Published in Biochemical and biophysical research communications (01-01-1984)“…Chick thymus cytosol glucocorticoid receptor complexed with [3H]-triamcinolone acetonide was heat-activated after treatment with diimidates of varying chain…”
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Kinetic deuterium isotope effects in glucocorticoid receptor activation
Published in Journal of receptor research (1984)“…Activation and deactivation of the chick thymus glucocorticoid receptor protein was studied in ordinary and heavy water by DNA-cellulose binding of the…”
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Kinetics of the glucocorticoid hormone-receptor interaction. False association constants determined in slowly equilibrating systems
Published in Biochimica et biophysica acta (16-05-1979)“…The usual way of in vitro determination of association constants for hormone-receptor complexes is criticized. It is shown that if incubation time is short,…”
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A new assay for antiphlogistic activity: zymosan-induced mouse ear inflammation
Published in Agents and Actions (01-07-1993)“…A new model of local inflammation has been developed: intradermal zymosan-induced mouse ear edema. The symptoms of inflammation induced by injecting zymosan…”
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A novel specific binding site for anxiolytic homophthalazines in the rat brain
Published in FEBS letters (17-08-1992)“…Radioligand binding studies were performed in order to elucidate the mechanism of action of anxiolytic-neuroleptic homophthalazines. Rat striatal membrane…”
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A novel specific binding site for homophthalazines in the rat brain
Published in European journal of pharmacology (12-05-1993)“…The specific binding sites of a homophthalazine, girisopam, in rat brain have been localized by qualitative and quantitative autoradiography. This substance…”
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Dependence of rate constants of the glucocorticoid hormone-receptor interaction on steroid structure
Published in Journal of steroid biochemistry (01-08-1982)“…Making use of the methods developed earlier [P. Arányi and V. Quiroga, J. steroid Biochem. 13, 1167-1172 (1980)] rate constants of the…”
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In vivo testing of potential anti-amnesic therapeutic agents by transgenic animal model
Published in Archiv für Tierzucht (1999)Get full text
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Characterization of the partially purified, ligand-free glucocorticoid receptor
Published in Biochimica et biophysica acta (04-09-1986)“…A new method was developed to synthesize a cortexolone-substituted affinity matrix, based on the fast, mild and quantitative reaction between…”
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Differential sensitivity to Arg side chain modification of IL-1 beta binding to type I and type II receptors
Published in Agents and Actions (01-03-1994)“…The central role of interleukin-1 (IL-1) in several disease processes, including fever and inflammation, makes the characterization of ligand-receptor…”
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Low levels of glucocorticoid binding sites in circulating lymphocytes of premature infants suffering from hyaline membrane disease
Published in Journal of steroid biochemistry (01-02-1985)“…The number and affinity of glucocorticoid binding sites in lymphocytes of newborns and prematures were determined by a whole cell [3H]dexamethasone binding…”
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Lymphocyte glucocorticoid receptors in cancer patients
Published in Oncology (1988)“…Glucocorticoid receptor concentration was determined in circulating lymphocytes of patients with benign and malignant tumors. It was not different from control…”
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