Search Results - "Apte, Simon"

Transformations of Nanomaterials in the Environment by Lowry, Gregory V, Gregory, Kelvin B, Apte, Simon C, Lead, Jamie R

“…Increasing use of engineered nanomaterials with novel properties relative to their bulk counterparts has generated a need to define their behaviors and impacts…”
Get full text

A Review of the Effect of Trace Metals on Freshwater Cyanobacterial Growth and Toxin Production by Facey, Jordan A, Apte, Simon C, Mitrovic, Simon M

“…Cyanobacterial blooms are becoming more common in freshwater systems, causing ecological degradation and human health risks through exposure to cyanotoxins…”
Get full text

Comparative Toxicity of Nanoparticulate ZnO, Bulk ZnO, and ZnCl2 to a Freshwater Microalga (Pseudokirchneriella subcapitata): The Importance of Particle Solubility by Franklin, Natasha M, Rogers, Nicola J, Apte, Simon C, Batley, Graeme E, Gadd, Gerald E, Casey, Philip S

“…Metal oxide nanoparticles are finding increasing application in various commercial products, leading to concerns for their environmental fate and potential…”
Get full text

Sorption, degradation and microbial toxicity of chemicals associated with hydraulic fracturing fluid and produced water in soils by Kookana, Rai S., Williams, Mike, Gregg, Adrienne, Semmler, Adelle, Du, Jun, Apte, Simon C.

“…Spills of hydraulic fracturing (HF) fluids and of produced water during unconventional gas extraction operations may cause soil contamination. We studied the…”
Get full text

On the mechanism of nanoparticulate CeO2 toxicity to freshwater algae by Angel, Brad M., Vallotton, Pascal, Apte, Simon C.

“…•Nanoparticulate CeO2 less toxic than micron-sized CeO2.•UV light filters prevented ROS generation by CeO2.•ROS not toxic mechanism: CeO2 toxicity was similar…”
Get full text

Assessing the importance of cobalt as a micronutrient for freshwater cyanobacteria by Facey, Jordan A., King, Josh J, Apte, Simon C, Mitrovic, Simon M., Posewitz, M.

“…Micronutrients play key roles in numerous metabolic processes in cyanobacteria. However, our understanding of whether the micronutrient cobalt influences the…”
Get full text

Defined Small Molecules Produced by Himalayan Medicinal Plants Display Immunomodulatory Properties by Wangchuk, Phurpa, Apte, Simon H, Smout, Michael J, Groves, Penny L, Loukas, Alex, Doolan, Denise L

“…Plant-derived compounds that modulate the immune responses are emerging as frontline treatment agents for cancer, infectious diseases and autoimmunity. Herein…”
Get full text

Toxicity of dissolved and precipitated forms of barium to a freshwater alga (Chlorella sp. 12) and water flea (Ceriodaphnia dubia) by Golding, Lisa A., McKnight, Kitty, Binet, Monique, Adams, Merrin, Apte, Simon C.

“…Barium is present at elevated concentrations in oil and gas produced waters, and there is no international water quality guideline value to assess the…”
Get full text

Genome-based vaccine design: the promise for malaria and other infectious diseases by Doolan, Denise L., Apte, Simon H., Proietti, Carla

“…[Display omitted] •Vaccines against complex pathogens and chronic diseases have proved challenging.•Rational vaccine design exploiting advances in genomics and…”
Get full text

Plasmodium vivax but Not Plasmodium falciparum Blood-Stage Infection in Humans Is Associated with the Expansion of a CD8+ T Cell Population with Cytotoxic Potential by Burel, Julie G, Apte, Simon H, McCarthy, James S, Doolan, Denise L

“…P. vivax and P. falciparum parasites display different tropism for host cells and induce very different clinical symptoms and pathology, suggesting that the…”
Get full text

Influence of Physicochemical Properties of Lipopeptide Adjuvants on the Immune Response: A Rationale for Engineering a Potent Vaccine by Eskandari, Sharareh, Pattinson, David J., Stephenson, Rachel J., Groves, Penny L., Apte, Simon H., Sedaghat, Bita, Chandurudu, Saranya, Doolan, Denise L., Toth, Istvan

“…Adjuvant development and understanding the physicochemical properties of particles and interpreting the subsequent immunological responses is a challenge faced…”
Get full text

Proteomic identification of the contents of small extracellular vesicles from in vivo Plasmodium yoelii infection by De Sousa, Karina P., Potriquet, Jeremy, Mulvenna, Jason, Sotillo, Javier, Groves, Penny L., Loukas, Alex, Apte, Simon H., Doolan, Denise L.

“…[Display omitted] •Total small extracellular vesicle (sEV) number and protein concentration positively correlated with parasitaemia.•Circulating sEVs contain…”
Get full text

Micronutrients as growth limiting factors in cyanobacterial blooms; a survey of freshwaters in South East Australia by Facey, Jordan A., Rogers, Terence A., Apte, Simon C., Mitrovic, Simon M.

“…The role of trace metal micronutrients in limiting cyanobacterial growth and structuring the phytoplankton community is becoming more evident. However, little…”
Get full text

New Insights Into Acidithiobacillus thiooxidans Sulfur Metabolism Through Coupled Gene Expression, Solution Chemistry, Microscopy, and Spectroscopy Analyses by Camacho, David, Frazao, Rodolfo, Fouillen, Aurélien, Nanci, Antonio, Lang, B Franz, Apte, Simon C, Baron, Christian, Warren, Lesley A

“…Here, we experimentally expand understanding of the reactions and enzymes involved in ATCC 19377 S and metabolism by developing models that integrate gene…”
Get full text

Derivation of a water quality guideline for aluminium in marine waters by Golding, Lisa A., Angel, Brad M., Batley, Graeme E., Apte, Simon C., Krassoi, Rick, Doyle, Chris J.

“…Metal risk assessment of industrialized harbors and coastal marine waters requires the application of robust water quality guidelines to determine the…”
Get full text

Single-Cell Profiling of Cells in the Lung of a Patient with Chronic Hypersensitivity Pneumonitis Reveals Inflammatory Niche with Abundant CD39+ T Cells with Functional ATPase Phenotype: A Case Study by de Silva, Tharushi Ayanthika, Apte, Simon, Voisey, Joanne, Spann, Kirsten, Tan, Maxine, Divithotawela, Chandima, Chambers, Daniel, O’Sullivan, Brendan

“…This study investigated immune cell characteristics in chronic hypersensitivity pneumonitis (HP), focusing on CD39-expressing cells’ impact on inflammation and…”
Get full text

Immunological Landscapes in Lung Transplantation: Insights from T Cell Profiling in BAL and PBMC by de Silva, Tharushi Ayanthika, Apte, Simon, Voisey, Joanne, Spann, Kirsten, Tan, Maxine, Chambers, Daniel, O'Sullivan, Brendan

“…Lung transplant recipients frequently encounter immune-related complications, including chronic lung allograft dysfunction (CLAD). Monitoring immune cells…”
Get full text

Novel Plasmodium antigens identified via genome-based antibody screen induce protection associated with polyfunctional T cell responses by Schussek, Sophie, Trieu, Angela, Apte, Simon H., Sidney, John, Sette, Alessandro, Doolan, Denise L.

“…The development of vaccines against complex intracellular pathogens, such as Plasmodium spp ., where protection is likely mediated by cellular immune…”
Get full text

Systems Approaches towards Molecular Profiling of Human Immunity by Burel, Julie G, Apte, Simon H, Doolan, Denise L

“…Systems immunology integrates cutting-edge technologies with bioinformatics to comprehensively interrogate the immune response to infection at an organismal…”
Get full text

Reduced Plasmodium Parasite Burden Associates with CD38+ CD4+ T Cells Displaying Cytolytic Potential and Impaired IFN-γ Production by Burel, Julie G, Apte, Simon H, Groves, Penny L, Klein, Kerenaftali, McCarthy, James S, Doolan, Denise L

“…Using a unique resource of samples from a controlled human malaria infection (CHMI) study, we identified a novel population of CD4+ T cells whose frequency in…”
Get full text