Search Results - "Aps, Luana R. M. M."
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Expression of a soluble IL-10 receptor enhances the therapeutic effects of a papillomavirus-associated antitumor vaccine in a murine model
Published in Cancer Immunology, Immunotherapy (01-05-2019)“…The presence of IL-10, produced either by tumor cells or immunosuppressive cells, is frequently associated with a poor prognosis for cancer progression. It may…”
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Branched Amphiphilic Cationic Oligopeptides Form Peptiplexes with DNA: A Study of Their Biophysical Properties and Transfection Efficiency
Published in Molecular pharmaceutics (02-03-2015)“…Over the past decade, peptides have emerged as a new family of potential carriers in gene therapy. Peptides are easy to synthesize and quite stable…”
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A therapeutic DNA vaccine and gemcitabine act synergistically to eradicate HPV-associated tumors in a preclinical model
Published in Oncoimmunology (01-01-2021)“…Although active immunotherapies are effective strategies to induce activation of CD8 + T cells, advanced stage tumors require further improvements for…”
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In vivo electroporation enhances vaccine-mediated therapeutic control of human papilloma virus-associated tumors by the activation of multifunctional and effector memory CD8+ T cells
Published in Vaccine (19-12-2017)“…In vivo electroporation (EP) has reignited the clinical interest on DNA vaccines as immunotherapeutic approaches to control different types of cancer. EP has…”
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Antigen Delivery to DEC205 + Dendritic Cells Induces Immunological Memory and Protective Therapeutic Effects against HPV-Associated Tumors at Different Anatomical Sites
Published in International journal of biological sciences (01-01-2021)“…The generation of successful anticancer vaccines relies on the ability to induce efficient and long-lasting immune responses to tumor antigens. In this…”
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Bacterial spores as particulate carriers for gene gun delivery of plasmid DNA
Published in Journal of biotechnology (20-06-2016)“…[Display omitted] •Bacterial spores can adsorb DNA on their surface after treatment with DODAB.•DNA-coated spores can be loaded into biolistic cartridges for…”
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Bacillus subtilis spores as adjuvants for DNA vaccines
Published in Vaccine (11-05-2015)“…Abstract Recently, Bacillus subtilis spores were shown to be endowed with strong adjuvant capacity when co-administered with purified antigenic proteins. In…”
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Enhanced therapeutic effects conferred by an experimental DNA vaccine targeting human papillomavirus-induced tumors
Published in Human gene therapy (01-10-2013)“…Human papillomavirus (HPV) infection is responsible for all cervical cancer cases, other anogenital cancers, and head and neck tumors. The epidemiological…”
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Abstract A62: In vivo electroporation improves the immune responses induced by a DNA vaccine and confers complete antitumor protection against HPV-associated tumors
Published in Clinical cancer research (01-01-2018)“…Cervical cancer associated with persistent papilloma virus infections (HPV) is a public health problem and represents the third most frequent type of cancer in…”
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