Search Results - "Apryshko, G N"

Synthesis and Cytotoxicity of Indole Derivatives of Betulin, Erythrodiol, and Uvaol by Khusnutdinova, E. F., Petrova, A. V., Apryshko, G. N., Kukovinets, O. S., Kazakova, O. B.

“…2,3-Indolotriterpenic alcohols have been synthesized for the first time by successive modification of 3-oxo triterpenic acids (Fisher reaction, reduction of…”
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The Synthesis and Selective Cytotoxicity of New Mannich Bases, Derivatives of 19- and 28-Alkynyltriterpenoids by Khusnutdinova, E. F., Apryshko, G. N., Petrova, A. V., Kukovinets, O. S., Kazakova, O. B.

“…New propargylamines were synthesized in 72–75% yields by the interaction of 19-alkynylbetulin and 28- O -propargyl glycinamide of oleanolic acid with…”
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Multilevel adaptive description of molecular graphs in the “structure-property” problem by Bekker, A. V., Suleimanov, A. A., Apryshko, G. N., Kumskov, M. I., Pugacheva, R. B.

“…A method for solving the “structure-property” problem is proposed based on the adaptive choice of molecule description and automatic selection of a feature…”
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The multilevel adaptive description of molecular graphs in “structure-property problem” by Bekker, A. V., Suleymanov, A. A., Apryshko, G. N., Kumskov, M. I.

“…Proposed and developed a method for solving the “structure-property” problem, which is based on an adaptive choice of the description of molecules and the…”
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Synthesis and cytotoxicity of triterpene seven-membered cyclic amines by Kazakova, O. B., Giniyatullina, G. V., Medvedeva, N. I., Lopatina, T. V., Baikova, I. P., Tolstikov, G. A., Apryshko, G. N.

“…3-Deoxy-3 a -homo-3 a -aza derivatives of betulin and erythrodiol have been synthesized from betulonic and oleanonic acids. 3-Deoxy-3 a -homo-3 a…”
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Synthesis and the antineoplastic activity of imidazolides of betulonic acid by Kazakova, O. B., Medvedeva, N. I., Lopatina, T. V., Apryshko, G. N., Pugacheva, R. B., Yavorskaya, N. P., Golubeva, I. S., Tolstikov, G. A.

“…Lupane C-28-imidazolides containing 3-oxo-, 3-hydroxyimino-, and 2-cyano-2,3-seco-4(23)-ene fragments in cycle A have been synthesized…”
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Synthesis and cytotoxicity of allobetulin derivatives by Kazakova, O. B., Smirnova, I. E., Khusnutdinova, E. F., Zhukova, O. S., Fetisova, L. V., Apryshko, G. N., Medvedeva, N. I., Yamansarov, E. Yu, Baikova, I. P., Nguyen, Thanh Tra, Thu, H. Do Thi

“…A variety of oxygen-, nitrogen-, sulfur-, and platinum-containing allobetulin derivatives, including those with different positions of double bonds in rings A…”
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Synthesis, structure, and pharmacological activity of (7R,8S)-epoxy-(13R,17R)-trioxolane abietic acid by Kazakova, O. B., Smirnova, I. E., Tkhu, H. Do Tkhi, Nguen, Tkhankh Tra, Apryshko, G. N., Zhukova, O. S., Medvedeva, N. I., Nazyrov, T. I., Tret’yakova, E. V., Chudov, I. V., Ismagilova, A. F., Suponitsky, K. Yu, Kazakov, D. V., Safarov, F. E., Tolstikov, G. A.

“…The synthesis of (7 R ,8 S )-epoxy-(13 R ,17 R )-trioxolane abietic acid was carried out and its structure was established by X-ray diffraction. The…”
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Synthesis and Anticancer Activity of Betulonic Acid Imidazolides by Kazakova, O B, Medvedeva, N I, Lopatina, T V, Apryshko, G N, Pugacheva, R B, Yavorskaya, N P, Golubeva, I S, Tolstikov, G A

“…Synthesis of lupane C28-imidazolides, contained 3-oxo-, 3-oximino- and 2-cyano-2,3-seco-4(23)-en-frag ments in cycle A was carried out. The most antitumor…”
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Information System for Antitumor Agents: Computer database biologic module by Apryshko, G. N.

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Synthesis and antitumor activity of aminopropoxy derivatives of betulin, erythrodiol, and uvaol by Kazakova, O. B., Giniyatullina, G. V., Tolstikov, G. A., Baikova, I. P., Zaprutko, L., Apryshko, G. N.

“…Aminopropoxy derivatives of betulin, erythrodiol, uvaol, and oleantriol have been synthesized by the cyanoethylation of the hydroxyl groups of triterpenoids…”
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Information system for antitumor agents: Computer database registration and nomenclature module by Apryshko, G. N.

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Synthesis and cytotoxicity of triterpenoid seven members cyclic amines by Kazakova, O B, Giniiatullina, G V, Medvedeva, N I, Lopatina, T V, Baĭkova, I P, Tolstikov, G A, Apryshko, G N

“…Synthesis of 3-deoxy-3a-homo-3a-aza-derivatives of betulin and erythrodiol from betulonic and oleanonic acids was carried out. The most antineoplastic activity…”
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Synthesis and cytotoxicity of allobetulin derivatives by Kazakova, O B, Smirnova, I E, Khusnutdinova, E F, Zhukova, O S, Fetisova, L V, Apryshko, G N, Medvedeva, N I, Iamansarov, E Iu, Baĭkova, I P, Nguen, Thanh Tra, Thu, Do Thi H

“…The synthesis and screening of antitumor activity in vitro (cytotoxicity) of various oxygen, nitrogen, sulfur and platinum-containing derivatives of…”
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Synthesis and antitumor activity of betulin, erythrodiol and uvaol aminopropoxy derivatives by Kazakova, O B, Giniiatullina, G V, Tolstikov, G A, Baĭkova, I P, Zaprutko, L, Apryshko, G N

“…The synthesis of aminopropoxy derivatives of betulin, erythrodiol, uvaol and oleantriol via cyanoethylation of triterpenoids hydroxyl groups and subsequent…”
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Synthesis, structure and farmacologycal activity of (7R,8S)-epoxy-(13R,17R)-trioxolaneabietic acid by Kazakova, O B, Smirnova, I E, Do Tkhi Tkhu, Kh, Tkhankh Tra Nguen, Apryshko, G N, Zhukova, O S, Medvedeva, N I, Nazyrov, T I, Tret'iakova, E V, Chudov, I V, Ismagilova, A F, Suponitskiĭ, K Iu, Kazakov, D V, Safarov, F E, Tolstikov, G A

“…The synthesis and X-ray diffraction established the structure of (7R,8S)-(see text for symbol)-(13R,17R)-trioxolaneabietic acid. Predicted by the computer…”
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Presentation of structural chemical information in a database on anticancer drugs by Pugachyova, R. B., Goncharenko, L. V., Blinova, V. G., Apryshko, G. N.

“…Approaches to the standard presentation of the structural formulae of substances in the anticancer drug database of the Blokhin RCRC, RAMS have been described…”
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Multilevel Adaptive Description of Molecular Graphs in the Structure―Property Problem by BEKKER, A. V, SULEIMANOV, A. A, APRYSHKO, G. N, KUMSKOV, M. I, PUGACHEVA, R. B

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New approaches to search for antitumoral compounds by Gerasimova, G K, Apryshko, G N, Reshetnikova, V V, Sidorova, T A, Solntseva, T I, Khorosheva, E V, Khabarov, S V, Baryshnikov, A Iu

“…The authors discuss the present-day state of search for antitumoral compounds at Blokhin Russian Oncological Research Center and promising approaches including…”
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DNA preparations as potential therapeutic agents by Pashuk, L. K., Apryshko, G. N., Treshchalina, E. M.

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