Search Results - "Apró, W."

High doses of anti‐inflammatory drugs compromise muscle strength and hypertrophic adaptations to resistance training in young adults by Lilja, M., Mandić, M., Apró, W., Melin, M., Olsson, K., Rosenborg, S., Gustafsson, T., Lundberg, T. R.

“…Aims This study tested the hypothesis that high doses of anti‐inflammatory drugs would attenuate the adaptive response to resistance training compared with low…”
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Glucosinolate-rich broccoli sprouts protect against oxidative stress and improve adaptations to intense exercise training by Flockhart, M., Nilsson, L.C., Tillqvist, E.N., Vinge, F., Millbert, F., Lännerström, J., Nilsson, P.H., Samyn, D., Apró, W., Sundqvist, M.L., Larsen, F.J.

“…Oxidative stress plays a vital role for the adaptive responses to physical training. However, excessive oxidative stress can precipitate cellular damage,…”
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Acute hypoxia attenuates resistance exercise‐induced ribosome signaling but does not impact satellite cell pool expansion in human skeletal muscle by Horwath, Oscar, Nordström, Fabian, Walden, Ferdinand, Apró, William, Moberg, Marcus

“…Cumulative evidence supports the hypothesis that hypoxia acts as a regulator of muscle mass. However, the underlying molecular mechanisms remain incompletely…”
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THRIFTY-A High-throughput Single Muscle Fiber Typing Method Based on Immunofluorescence Detection by Edman, Sebastian, Horwath, Oscar, Apró, William

“…Skeletal muscle consists of a mixture of fiber types with different functional and metabolic characteristics. The relative composition of these muscle fiber…”
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Pro-Brain-Derived Neurotrophic Factor (BDNF), but Not Mature BDNF, Is Expressed in Human Skeletal Muscle: Implications for Exercise-Induced Neuroplasticity by Edman, Sebastian, Horwath, Oscar, Van der Stede, Thibaux, Blackwood, Sarah Joan, Moberg, Isabel, Strömlind, Henrik, Nordström, Fabian, Ekblom, Maria, Katz, Abram, Apró, William, Moberg, Marcus

“…Exercise promotes brain plasticity partly by stimulating increases in mature brain-derived neurotrophic factor (mBDNF), but the role of the pro-BDNF isoform in…”
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Three hours of Moderate Intensity Exercise Training Reduces Glucose Tolerance in Endurance Trained Athletes by Flockhart, M, Tischer, D, Nilsson, LC, Blackwood, SJ, Ekblom, B, Katz, A, Apró, W, Larsen, FJ

“…Objectives: It is well accepted that exercise training improves glucose uptake and insulin sensitivity, and that endurance trained athletes in general show a…”
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Influence of supplementation with branched-chain amino acids in combination with resistance exercise on p70S⁶ kinase phosphorylation in resting and exercising human skeletal muscle by Apró, W, Blomstrand, E

“…Skeletal muscle growth is thought to be regulated by the mammalian target of rapamycin (mTOR) pathway, which can be activated by resistance exercise and…”
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Insulin resistance after a 3-day fast is associated with an increased capacity of skeletal muscle to oxidize lipids by Blackwood, Sarah J, Horwath, Oscar, Moberg, Marcus, Pontén, Marjan, Apró, William, Ekblom, Maria M, Larsen, Filip J, Katz, Abram

“…There is a debate on whether lipid-mediated insulin resistance derives from an increased or decreased capacity of muscle to oxidize fats. Here, we examine the…”
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Limited effect of over-the-counter doses of ibuprofen on mechanisms regulating muscle hypertrophy during resistance training in young adults by Lilja, Mats, Moberg, Marcus, Apró, William, Martínez-Aranda, Luis Manuel, Rundqvist, Håkan, Langlet, Billy, Gustafsson, Thomas, Lundberg, Tommy R

“…We have previously shown that maximal over-the-counter doses of ibuprofen, compared with low doses of acetylsalicylic acid, reduce muscle hypertrophy in young…”
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Influence of supplementation with branched-chain amino acids in combination with resistance exercise on p70S6 kinase phosphorylation in resting and exercising human skeletal muscle: BCAA and p70S6k signalling in muscle by Apró, W., Blomstrand, E.

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Excessive exercise training causes mitochondrial functional impairment and decreases glucose tolerance in healthy volunteers by Flockhart, Mikael, Nilsson, Lina C., Tais, Senna, Ekblom, Björn, Apró, William, Larsen, Filip J.

“…Exercise training positively affects metabolic health through increased mitochondrial oxidative capacity and improved glucose regulation and is the first line…”
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Variability in vastus lateralis fiber type distribution, fiber size, and myonuclear content along and between the legs by Horwath, Oscar, Envall, Helena, Röja, Julia, Emanuelsson, Eric B., Sanz, Gema, Ekblom, Björn, Apró, William, Moberg, Marcus

“…This study provides a comprehensive analysis of the variability of key human skeletal muscle fiber characteristics in multiple sites along and between the…”
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THRIFTY: a novel high‐throughput method for rapid fibre type identification of isolated skeletal muscle fibres by Horwath, Oscar, Edman, Sebastian, Andersson, Alva, Larsen, Filip J., Apró, William

“…Fibre type‐specific analyses are required for broader understanding of muscle physiology, but such analyses are difficult to conduct due to the extreme time…”
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The lactate receptor GPR81 is predominantly expressed in type II human skeletal muscle fibers: potential for lactate autocrine signaling by Nordström, Fabian, Liegnell, Rasmus, Apró, William, Blackwood, Sarah J, Katz, Abram, Moberg, Marcus

“…G -coupled protein receptor 81 (GPR81) was first identified in adipocytes as a receptor for l-lactate, which upon binding inhibits cyclicAMP (cAMP)-protein…”
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Influence of sex and fiber type on the satellite cell pool in human skeletal muscle by Horwath, Oscar, Moberg, Marcus, Larsen, Filip J., Philp, Andrew, Apró, William, Ekblom, Björn

“…The repair, remodeling, and regeneration of myofibers are dependent on satellite cells (SCs), although, the distribution of SCs in different fiber types of…”
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Resistance exercise induced mTORC1 signaling is not impaired by subsequent endurance exercise in human skeletal muscle by Apró, William, Wang, Li, Pontén, Marjan, Blomstrand, Eva, Sahlin, Kent

“…The current dogma is that the muscle adaptation to resistance exercise is blunted when combined with endurance exercise. The suggested mechanism (based on…”
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Activation of mTORC1 by leucine is potentiated by branched-chain amino acids and even more so by essential amino acids following resistance exercise by Moberg, Marcus, Apró, William, Ekblom, Björn, van Hall, Gerrit, Holmberg, Hans-Christer, Blomstrand, Eva

“…Protein synthesis is stimulated by resistance exercise and intake of amino acids, in particular leucine. Moreover, activation of mammalian target of rapamycin…”
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Intake of branched-chain amino acids influences the levels of MAFbx mRNA and MuRF-1 total protein in resting and exercising human muscle by Borgenvik, Marcus, Apró, William, Blomstrand, Eva

“…Resistance exercise and amino acids are two major factors that influence muscle protein turnover. Here, we examined the effects of resistance exercise and…”
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Fiber type-specific hypertrophy and increased capillarization in skeletal muscle following testosterone administration in young women by Horwath, Oscar, Apró, William, Moberg, Marcus, Godhe, Manne, Helge, Torbjörn, Ekblom, Maria, Hirschberg, Angelica Lindén, Ekblom, Björn

“…It is well established that testosterone administration induces muscle fiber hypertrophy and myonuclear addition in men; however, it remains to be determined…”
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Acute normobaric hypoxia blunts contraction‐mediated mTORC1‐ and JNK‐signaling in human skeletal muscle by Moberg, Marcus, Apró, William, Horwath, Oscar, Hall, Gerrit, Blackwood, Sarah Joan, Katz, Abram

“…Aim Hypoxia has been shown to reduce resistance exercise‐induced stimulation of protein synthesis and long‐term gains in muscle mass. However, the mechanism…”
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