Search Results - "Appleton, C.T."

Reliability and concurrent validity of three-dimensional ultrasound for quantifying knee cartilage volume by Papernick, S., Dima, R., Gillies, D.J., Appleton, C.T., Fenster, A.

“…The goal of this study was to test the reliability and validity of a handheld mechanical three-dimensional (3D) ultrasound (US) device for quantifying femoral…”
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“You don't put it down to arthritis”: A qualitative study of the first symptoms recalled by individuals with knee osteoarthritis by King, L.K., Mahmoudian, A., Waugh, E.J., Stanaitis, I., Gomes, M., Hung, V., MacKay, C., Liew, J.W., Wang, Q., Turkiewicz, A., Haugen, I.K., Appleton, C.T., Lohmander, S., Englund, M., Runhaar, J., Neogi, T., Hawker, G.A.

“…As part of the first phase of the OARSI Early-stage Symptomatic Knee Osteoarthritis (EsSKOA) initiative, we explored the first symptoms and experiences…”
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086 THE ROLE OF TRANSFORMING GROWTH FACTOR ALPHA IN A MOUSE MODEL OF OSTEOARTHRITIS by Usmani, S.E, Appleton, C.T, Welch, I.D, Beier, F

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215 TRANSFORMING GROWTH FACTOR ALPHA AND ENDOTHELIN RECEPTOR A SIGNALING IN OSTEOARTHRITIS by Usmani, S.E, Appleton, C.T, Beier, F

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Osteoarthritis year in review 2017: biology by Appleton, C.T.

“…This Year in Review was derived from a personal selection of articles investigating biological mechanisms of osteoarthritis (OA) and presented at the OARSI…”
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Impaired synovial macrophage-mediated efferocytosis in a rat model of post-traumatic knee osteoarthritis by Del Sordo, L., Sodhi, E., Blackler, G., Grol, M., Heit, B., Appleton, C.T.

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OMERACT-OARSI responder analysis after medial opening wedge high tibial osteotomy and predictors of response by Primeau, C.A., Birmingham, T.B., Appleton, C.T., Leitch, K.M., Giffin, J.R.

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Effect of high tibial osteotomy on knee articular cartilage composition and effusion synovitis by Atkinson, H.F., Birmingham, T.B., Schulz, J.M., Appleton, C.T., Giffin, J.R.

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SYNOVIAL EFFUSION AND HYPERPLASIA: DISTINCT CONSTRUCTS IN KNEE OSTEOARTHRITIS by Dima, R.S., Birmingham, T., Philpott, H., Bryant, D., Fenster, A., Appleton, C.T.

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Candidate Items For Classifying Early-Stage Knee Osteoarthritis: Results From An International Expert Survey by Mahmoudian, A., King, L.K., Liew, J.W., Wang, Q., Appleton, C.T., Englund, M., Haugen, I.K., Lohmander, L.S., Runhaar, J., Turkiewicz, A., Neogi, T., Hawker, G.

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Reliability and sensitivity to change of bone marrow lesion scores using the knee inflammation MRI scoring system (KIMRISS) before and after high tibial osteotomy by Schulz, J.M., Birmingham, T.B., Maksymowych, W.P., Lambert, R.G., Pritchett, S., Beier, F., Giffin, J.R., Appleton, C.T.

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Transient anabolic effects of synovium in early post-traumatic osteoarthritis: a novel ex vivo joint tissue co-culture system for investigating synovium-chondrocyte interactions by Lai-Zhao, Y., Pitchers, K.K., Appleton, C.T.

“…Osteoarthritis (OA) is a serious joint disease with no disease-modifying medical treatment. To develop treatments targeting synovium, we must improve our…”
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Sequencing identifies a distinct signature of circulating microRNAs in early radiographic knee osteoarthritis by Ali, S.A., Gandhi, R., Potla, P., Keshavarzi, S., Espin-Garcia, O., Shestopaloff, K., Pastrello, C., Bethune-Waddell, D., Lively, S., Perruccio, A.V., Rampersaud, Y.R., Veillette, C., Rockel, J.S., Jurisica, I., Appleton, C.T., Kapoor, M.

“…MicroRNAs act locally and systemically to impact osteoarthritis (OA) pathophysiology, but comprehensive profiling of the circulating miRNome in early vs late…”
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“You Don’t Put It Down To Arthritis”: Qualitative Analysis Of The First Symptoms Recalled By Individuals With Knee Osteoarthritis by King, L.K., Mahmoudian, A., Waugh, E.J., MacKay, C., Stanaitis, I., Liew, J.W., Wang, Q., Turkiewicz, A., Haugen, I.K., Appleton, C.T., Lohmander, S., Englund, M., Runhaar, J., Neogi, T., Hawker, G.A.

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Osteoarthritis, cerebrovascular dysfunction and the common denominator of inflammation: a narrative review by Al-Khazraji, B.K., Appleton, C.T., Beier, F., Birmingham, T.B., Shoemaker, J.K.

“…Population-based cohort studies suggest an association between osteoarthritis (OA) and cerebrovascular disease, yet the mechanisms underlying vascular…”
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Association between changes in knee load and effusion-synovitis: evidence of mechano-inflammation in knee osteoarthritis using high tibial osteotomy as a model by Atkinson, H.F., Birmingham, T.B., Primeau, C.A., Schulz, J.M., Appleton, C.T., Pritchett, S.L., Giffin, J.R.

“…Although mechanically-induced inflammation is an appealing explanation linking different etiologic factors in osteoarthritis (OA), clinical research…”
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Synovial tissue perivascular edema is associated with altered gait patterns in patients with knee osteoarthritis by Philpott, H.T., Carter, M.M., Birmingham, T.B., Pinto, R., Primeau, C.A., Giffin, J.R., Lanting, B.A., Appleton, C.T.

“…To explore mechanisms of mechanoinflammation, we investigated the association between the presence of knee synovial perivascular edema and gait biomechanics…”
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Multi-centre modified Delphi exercise to identify candidate items for classifying early-stage symptomatic knee osteoarthritis by King, L.K., Liew, J.W., Mahmoudian, A., Wang, Q., Jansen, N.E.J., Stanaitis, I., Hung, V., Berenbaum, F., Das, S., Ding, C., Emery, C.A., Filbay, S.R., Hochberg, M.C., Ishijima, M., Kloppenburg, M., Lane, N.E., Losina, E., Mobasheri, A., Turkiewicz, A., Runhaar, J., Haugen, I.K., Appleton, C.T., Lohmander, L.S., Englund, M., Neogi, T., Hawker, G.A.

“…To generate a list of candidate items potentially useful for discriminating individuals with Early-stage Symptomatic Knee Osteoarthritis (EsSKOA) from those…”
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Supportive Evidence For The Potential For Novel Biodiscovery In Osteoarthritis Through The Stepup Oa Consortium by Perry, T.A., Deng, Y., Hulley, P., Maciewicz, R.A., Mitchelmore, J., Perry, D., Larsson, S., Lemire, S., Struglics, A., Appleton, C.T., Kluzek, S., Arden, N.K., Felson, D.T., Marsden, B., Tom, B.D., Bondi, L., Kapoor, M., Kumar, V., Lohmander, L.S., Welting, T.J., Walsh, D.A., Valdes, A.M., Jostins-Dean, L., Watt, F.E., Vincent, T.L.

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ANGIOGENESIS AND ENDOTHELIAL DYSFUNCTION: SYNOVIAL VASCULAR PATHOLOGY IS ASSOCIATED WITH SURROGATE MEASURES OF KNEE LOAD DURING WALKING by Carter, M.M., Birmingham, T.B., Philpott, H.T., Giffin, J.R., Lanting, B.A., Appleton, C.T.

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