Search Results - "Appleby, Peter A."

A model of chemotaxis and associative learning in C. elegans by Appleby, Peter A.

“…The nematode C. elegans has attracted a great deal of interest from the neuroscience community due to the simplicity of its nervous system, which in the…”
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Functional expression of purinergic P2 receptors and transient receptor potential channels by the human urothelium by Shabir, Saqib, Cross, William, Kirkwood, Lisa A, Pearson, Joanna F, Appleby, Peter A, Walker, Dawn, Eardley, Ian, Southgate, Jennifer

“…In addition to its role as a physical barrier, the urothelium is considered to play an active role in mechanosensation. A key mechanism is the release of…”
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The role of additive neurogenesis and synaptic plasticity in a hippocampal memory model with grid-cell like input by Appleby, Peter A, Kempermann, Gerd, Wiskott, Laurenz

“…Recently, we presented a study of adult neurogenesis in a simplified hippocampal memory model. The network was required to encode and decode memory patterns…”
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Triphasic spike-timing-dependent plasticity organizes networks to produce robust sequences of neural activity by Waddington, Amelia, Appleby, Peter A, De Kamps, Marc, Cohen, Netta

“…Synfire chains have long been proposed to generate precisely timed sequences of neural activity. Such activity has been linked to numerous neural functions…”
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Stable competitive dynamics emerge from multispike interactions in a stochastic model of spike-timing-dependent plasticity by Appleby, Peter A, Elliott, Terry

“…In earlier work we presented a stochastic model of spike-timing-dependent plasticity (STDP) in which STDP emerges only at the level of temporal or spatial…”
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Multispike interactions in a stochastic model of spike-timing-dependent plasticity by Appleby, Peter A, Elliott, Terry

“…Recently we presented a stochastic, ensemble-based model of spike-timing-dependent plasticity. In this model, single synapses do not exhibit plasticity…”
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The role of multiple chemotactic mechanisms in a model of chemotaxis in C. elegans: different mechanisms are specialised for different environments by Appleby, Peter A.

“…Unlike simpler organisms, C. elegans possesses several distinct chemosensory pathways and chemotactic mechanisms. These mechanisms and pathways are…”
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Sources of variability in cytosolic calcium transients triggered by stimulation of homogeneous uro-epithelial cell monolayers by Appleby, Peter A., Shabir, Saqib, Southgate, Jennifer, Walker, Dawn

“…Epithelial tissue structure is the emergent outcome of the interactions between large numbers of individual cells. Experimental cell biology offers an…”
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Cell-type-specific modelling of intracellular calcium signalling: a urothelial cell model by Appleby, Peter A., Shabir, Saqib, Southgate, Jennifer, Walker, Dawn

“…Calcium signalling plays a central role in regulating a wide variety of cell processes. A number of calcium signalling models exist in the literature that are…”
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Additive neurogenesis as a strategy for avoiding interference in a sparsely-coding dentate gyrus by Appleby, Peter A., Wiskott, Laurenz

“…Recently we presented a model of additive neurogenesis in a linear, feedforward neural network that performed an encoding-decoding memory task in a changing…”
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Synaptic and temporal ensemble interpretation of spike-timing-dependent plasticity by Appleby, Peter A, Elliott, Terry

“…We postulate that a simple, three-state synaptic switch governs changes in synaptic strength at individual synapses. Under this switch rule, we show that a…”
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Emergence of synfire chains with triphasic spike-time-dependent plasticity by Waddington, Amelia, Appleby, Peter A, deKamps, Marc, Cohen, Netta

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The Role of Additive Neurogenesis and Synaptic Plasticity in a Hippocampal Memory Model with Grid-Cell Like Input: e1001063 by Appleby, Peter A, Kempermann, Gerd, Wiskott, Laurenz

“…Recently, we presented a study of adult neurogenesis in a simplified hippocampal memory model. The network was required to encode and decode memory patterns…”
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A computational model of associative learning and chemotaxis in the nematode worm C. elegans by Appleby, Peter A, Cohen, Netta

“…[...]contrary to the prevailing view in the C. elegans community, plasticity in our model of chemotaxis is expressed at a neuronal rather than synaptic level…”
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Fast Approximate Bayesian Contextual Cold Start Learning (FAB-COST) by McKenzie, Jack R, Appleby, Peter A, House, Thomas, Walton, Neil

“…Cold-start is a notoriously difficult problem which can occur in recommendation systems, and arises when there is insufficient information to draw inferences…”
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