Search Results - "Appelmelk, Ben J."

Helicobacter pylori metabolites exacerbate gastritis through C-type lectin receptors by Nagata, Masahiro, Toyonaga, Kenji, Ishikawa, Eri, Haji, Shojiro, Okahashi, Nobuyuki, Takahashi, Masatomo, Izumi, Yoshihiro, Imamura, Akihiro, Takato, Koichi, Ishida, Hideharu, Nagai, Shigenori, Illarionov, Petr, Stocker, Bridget L., Timmer, Mattie S.M., Smith, Dylan G.M., Williams, Spencer J., Bamba, Takeshi, Miyamoto, Tomofumi, Arita, Makoto, Appelmelk, Ben J., Yamasaki, Sho

“…Helicobacter pylori causes gastritis, which has been attributed to the development of H. pylori–specific T cells during infection. However, the mechanism…”
Get full text

Type VII secretion - mycobacteria show the way by Bitter, Wilbert, Abdallah, Abdallah M, Gey van Pittius, Nicolaas C, DiGiuseppe Champion, Patricia A, Cox, Jeffery, Luirink, Joen, Vandenbroucke-Grauls, Christina M. J. E, Appelmelk, Ben J

“…Recent evidence shows that mycobacteria have developed novel and specialized secretion systems for the transport of extracellular proteins across their…”
Get full text

PPE and PE_PGRS proteins of Mycobacterium marinum are transported via the type VII secretion system ESX‐5 by Abdallah, Abdallah M., Verboom, Theo, Weerdenburg, Eveline M., Gey van Pittius, Nicolaas C., Mahasha, Phetole W., Jiménez, Connie, Parra, Marcela, Cadieux, Nathalie, Brennan, Michael J., Appelmelk, Ben J., Bitter, Wilbert

“…Summary ESX‐5 is one of the five type VII secretion systems found in mycobacteria. These secretion systems are also known as ESAT‐6‐like secretion systems…”
Get full text

Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins by Sani, Musa, Houben, Edith N G, Geurtsen, Jeroen, Pierson, Jason, de Punder, Karin, van Zon, Maaike, Wever, Brigitte, Piersma, Sander R, Jiménez, Connie R, Daffé, Mamadou, Appelmelk, Ben J, Bitter, Wilbert, van der Wel, Nicole, Peters, Peter J

“…The cell envelope of mycobacteria, a group of Gram positive bacteria, is composed of a plasma membrane and a Gram-negative-like outer membrane containing…”
Get full text

Deciphering the molecular basis of mycobacteria and lipoglycan recognition by the C-type lectin Dectin-2 by Decout, Alexiane, Silva-Gomes, Sandro, Drocourt, Daniel, Blattes, Emilyne, Rivière, Michel, Prandi, Jacques, Larrouy-Maumus, Gérald, Caminade, Anne-Marie, Hamasur, Beston, Källenius, Gunilla, Kaur, Devinder, Dobos, Karen M., Lucas, Megan, Sutcliffe, Iain C., Besra, Gurdyal S., Appelmelk, Ben J., Gilleron, Martine, Jackson, Mary, Vercellone, Alain, Tiraby, Gérard, Nigou, Jérôme

“…Dectin-2 is a C-type lectin involved in the recognition of several pathogens such as Aspergillus fumigatus , Candida albicans , Schistosoma mansonii , and…”
Get full text

Inorganic Phosphate Limitation Modulates Capsular Polysaccharide Composition in Mycobacteria by van de Weerd, Robert, Boot, Maikel, Maaskant, Janneke, Sparrius, Marion, Verboom, Theo, van Leeuwen, Lisanne M., Burggraaf, Maroeska J., Paauw, Nanne J., Dainese, Elisa, Manganelli, Riccardo, Bitter, Wilbert, Appelmelk, Ben J., Geurtsen, Jeroen

“…Mycobacterium tuberculosis is protected by an unusual and highly impermeable cell envelope that is critically important for the successful colonization of the…”
Get full text

Molecular mimicry between Helicobacter pylori antigens and H+, K+ --adenosine triphosphatase in human gastric autoimmunity by Amedei, Amedeo, Bergman, Mathijs P, Appelmelk, Ben J, Azzurri, Annalisa, Benagiano, Marisa, Tamburini, Carlo, van der Zee, Ruurd, Telford, John L, Vandenbroucke-Grauls, Christina M J E, D'Elios, Mario M, Del Prete, Gianfranco

“…Autoimmune gastritis and Helicobacter pylori-associated gastric atrophy develop through similar mechanisms involving the proton pump H+,K+-adenosine…”
Get full text

Role of Phosphatidylinositol Mannosides in the Interaction between Mycobacteria and DC-SIGN by Driessen, Nicole N, Ummels, Roy, Maaskant, Janneke J, Gurcha, Sudagar S, Besra, Gurdyal S, Ainge, Gary D, Larsen, David S, Painter, Gavin F, Vandenbroucke-Grauls, Christina M.J.E, Geurtsen, Jeroen, Appelmelk, Ben J

“…The C-type lectin dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN) is the major receptor on DCs for mycobacteria…”
Get full text

truncated lipoglycan from mycobacteria with altered immunological properties by Birch, Helen L, Alderwick, Luke J, Appelmelk, Ben J, Maaskant, Janneke, Bhatt, Apoorva, Singh, Albel, Nigou, Jerome, Eggeling, Lothar, Geurtsen, Jeroen, Besra, Gurdyal S

“…Maintenance of cell-wall integrity in Mycobacterium tuberculosis is essential and is the target of several antitubercular drugs. For example, ethambutol…”
Get full text

Structure and Function of RNase AS, a Polyadenylate-Specific Exoribonuclease Affecting Mycobacterial Virulence In Vivo by Romano, Maria, van de Weerd, Robert, Brouwer, Femke C.C., Roviello, Giovanni N., Lacroix, Ruben, Sparrius, Marion, van den Brink-van Stempvoort, Gunny, Maaskant, Janneke J., van der Sar, Astrid M., Appelmelk, Ben J., Geurtsen, Jeroen J., Berisio, Rita

“…The cell-envelope of Mycobacterium tuberculosis plays a key role in bacterial virulence and antibiotic resistance. Little is known about the molecular…”
Get full text

Gastric autoimmunity: the role of Helicobacter pylori and molecular mimicry by D'Elios, Mario M., Appelmelk, Ben J., Amedei, Amedeo, Bergman, Mathijs P., Prete, Gianfranco Del

“…Pathogens can induce autoreactive T cells to initiate autoimmune disease by several mechanisms. Pathogen-induced inflammation results in the enhanced…”
Get full text

Lipoarabinomannan and related glycoconjugates: structure, biogenesis and role in Mycobacterium tuberculosis physiology and host–pathogen interaction by Mishra, Arun K., Driessen, Nicole N., Appelmelk, Ben J., Besra, Gurdyal S.

“…Abstract Approximately one third of the world's population is infected with Mycobacterium tuberculosis, the causative agent of tuberculosis. This bacterium has…”
Get full text

Variations in Helicobacter pylori Lipopolysaccharide To Evade the Innate Immune Component Surfactant Protein D by Khamri, Wafa, Moran, Anthony P, Worku, Mulugeta L, Karim, Q. Najma, Walker, Marjorie M, Annuk, Heidi, Ferris, John A, Appelmelk, Ben J, Eggleton, Paul, Reid, Kenneth B. M, Thursz, Mark R

“…Helicobacter pylori is a common and persistent human pathogen of the gastric mucosa. Surfactant protein D (SP-D), a component of innate immunity, is expressed…”
Get full text

Coordinate regulation of virulence and metabolic genes by the transcription factor HbhR in Mycobacterium marinum by Raze, Dominique, Segers, Jérôme, Mille, Céline, Slupek, Stéphanie, Lecher, Sophie, Coutte, Loïc, Antoine, Rudy, Ducrocq, Lucie, Rouanet, Carine, Appelmelk, Ben J., Locht, Camille

“…Summary The heparin‐binding hemagglutinin (HBHA) is a multifunctional protein involved in adherence of Mycobacterium tuberculosis to non‐phagocytic cells and…”
Get full text

Phase Variation in the Helicobacter pylori Phospholipase A Gene and Its Role in Acid Adaptation by TANNAES, Tone, DEKKER, Niek, BUKHOLM, Geir, BIJLSMA, Jetta J. E, APPELMELK, Ben J

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Limited Role of Lipopolysaccharide Lewis Antigens in Adherence of Helicobacter pylori to the Human Gastric Epithelium by Mahdavi, Jafar, Borén, Thomas, Vandenbroucke-Grauls, Christina, Appelmelk, Ben J

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Identification of mycobacterial alpha-glucan as a novel ligand for DC-SIGN: involvement of mycobacterial capsular polysaccharides in host immune modulation by Geurtsen, Jeroen, Chedammi, Sunita, Mesters, Joram, Cot, Marlène, Driessen, Nicole N, Sambou, Tounkang, Kakutani, Ryo, Ummels, Roy, Maaskant, Janneke, Takata, Hiroki, Baba, Otto, Terashima, Tatsuo, Bovin, Nicolai, Vandenbroucke-Grauls, Christina M J E, Nigou, Jérôme, Puzo, Germain, Lemassu, Anne, Daffé, Mamadou, Appelmelk, Ben J

“…Mycobacterium tuberculosis possesses a variety of immunomodulatory factors that influence the host immune response. When the bacillus encounters its target…”
Get full text

A specific secretion system mediates PPE41 transport in pathogenic mycobacteria by Abdallah, Abdallah M., Verboom, Theo, Hannes, Fredericke, Safi, Mohamad, Strong, Michael, Eisenberg, David, Musters, René J. P., Vandenbroucke‐Grauls, Christina M. J. E., Appelmelk, Ben J., Luirink, Joen, Bitter, Wilbert

“…Summary Mycobacterial genomes contain two unique gene families, the so‐called PE and PPE gene families, which are highly expanded in the pathogenic members of…”
Get full text

Cutting Edge: Carbohydrate Profiling Identifies New Pathogens That Interact with Dendritic Cell-Specific ICAM-3-Grabbing Nonintegrin on Dendritic Cells by Appelmelk, Ben J, van Die, Irma, van Vliet, Sandra J, Vandenbroucke-Grauls, Christina M. J. E, Geijtenbeek, Teunis B. H, van Kooyk, Yvette

“…Dendritic cells (DC) are instrumental in handling pathogens for processing and presentation to T cells, thus eliciting an appropriate immune response. C-type…”
Get full text

Helicobacter pylori modulates the T helper cell 1/T helper cell 2 balance through phase-variable interaction between lipopolysaccharide and DC-SIGN by Bergman, Mathijs P, Engering, Anneke, Smits, Hermelijn H, van Vliet, Sandra J, van Bodegraven, Ad A, Wirth, Hans-Peter, Kapsenberg, Martien L, Vandenbroucke-Grauls, Christina M J E, van Kooyk, Yvette, Appelmelk, Ben J

“…The human gastric pathogen Helicobacter pylori spontaneously switches lipopolysaccharide (LPS) Lewis (Le) antigens on and off (phase-variable expression), but…”
Get full text