Search Results - "Appelbaum, Elizabeth"

Identification of a Novel TP53 Cancer Susceptibility Mutation Through Whole-Genome Sequencing of a Patient With Therapy-Related AML by Link, Daniel C, Schuettpelz, Laura G, Shen, Dong, Wang, Jinling, Walter, Matthew J, Kulkarni, Shashikant, Payton, Jacqueline E, Ivanovich, Jennifer, Goodfellow, Paul J, Le Beau, Michelle, Koboldt, Daniel C, Dooling, David J, Fulton, Robert S, Bender, R. Hugh F, Fulton, Lucinda L, Delehaunty, Kimberly D, Fronick, Catrina C, Appelbaum, Elizabeth L, Schmidt, Heather, Abbott, Rachel, O’Laughlin, Michelle, Chen, Ken, McLellan, Michael D, Varghese, Nobish, Nagarajan, Rakesh, Heath, Sharon, Graubert, Timothy A, Ding, Li, Ley, Timothy J, Zambetti, Gerard P, Wilson, Richard K, Mardis, Elaine R

“…CONTEXT The identification of patients with inherited cancer susceptibility syndromes facilitates early diagnosis, prevention, and treatment. However, in many…”
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Mapping and characterization of structural variation in 17,795 human genomes by Abel, Haley J., Larson, David E., Regier, Allison A., Chiang, Colby, Das, Indraniel, Kanchi, Krishna L., Layer, Ryan M., Neale, Benjamin M., Salerno, William J., Reeves, Catherine, Buyske, Steven, Matise, Tara C., Muzny, Donna M., Zody, Michael C., Lander, Eric S., Dutcher, Susan K., Stitziel, Nathan O., Hall, Ira M.

“…A key goal of whole-genome sequencing for studies of human genetics is to interrogate all forms of variation, including single-nucleotide variants, small…”
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Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer by Cui Zhou, Daniel, Jayasinghe, Reyka G., Chen, Siqi, Herndon, John M., Iglesia, Michael D., Navale, Pooja, Wendl, Michael C., Caravan, Wagma, Sato, Kazuhito, Storrs, Erik, Mo, Chia-Kuei, Liu, Jingxian, Southard-Smith, Austin N., Wu, Yige, Naser Al Deen, Nataly, Baer, John M., Fulton, Robert S., Wyczalkowski, Matthew A., Liu, Ruiyang, Fronick, Catrina C., Fulton, Lucinda A., Shinkle, Andrew, Thammavong, Lisa, Zhu, Houxiang, Sun, Hua, Wang, Liang-Bo, Li, Yize, Zuo, Chong, McMichael, Joshua F., Davies, Sherri R., Appelbaum, Elizabeth L., Robbins, Keenan J., Chasnoff, Sara E., Yang, Xiaolu, Reeb, Ashley N., Oh, Clara, Serasanambati, Mamatha, Lal, Preet, Varghese, Rajees, Mashl, Jay R., Ponce, Jennifer, Terekhanova, Nadezhda V., Yao, Lijun, Wang, Fang, Chen, Lijun, Schnaubelt, Michael, Lu, Rita Jui-Hsien, Schwarz, Julie K., Puram, Sidharth V., Kim, Albert H., Song, Sheng-Kwei, Shoghi, Kooresh I., Lau, Ken S., Ju, Tao, Chen, Ken, Chatterjee, Deyali, Hawkins, William G., Zhang, Hui, Achilefu, Samuel, Chheda, Milan G., Oh, Stephen T., Gillanders, William E., Chen, Feng, DeNardo, David G., Fields, Ryan C., Ding, Li

“…Pancreatic ductal adenocarcinoma is a lethal disease with limited treatment options and poor survival. We studied 83 spatial samples from 31 patients (11…”
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Genome remodelling in a basal-like breast cancer metastasis and xenograft by Wilson, Richard K, Ding, Li, Ellis, Matthew J, Li, Shunqiang, Larson, David E, Chen, Ken, Wallis, John W, Harris, Christopher C, McLellan, Michael D, Fulton, Robert S, Fulton, Lucinda L, Abbott, Rachel M, Hoog, Jeremy, Dooling, David J, Koboldt, Daniel C, Schmidt, Heather, Kalicki, Joelle, Zhang, Qunyuan, Chen, Lei, Lin, Ling, Wendl, Michael C, McMichael, Joshua F, Magrini, Vincent J, Cook, Lisa, McGrath, Sean D, Vickery, Tammi L, Appelbaum, Elizabeth, DeSchryver, Katherine, Davies, Sherri, Guintoli, Therese, Lin, Li, Crowder, Robert, Tao, Yu, Snider, Jacqueline E, Smith, Scott M, Dukes, Adam F, Sanderson, Gabriel E, Pohl, Craig S, Delehaunty, Kim D, Fronick, Catrina C, Pape, Kimberley A, Reed, Jerry S, Robinson, Jody S, Hodges, Jennifer S, Schierding, William, Dees, Nathan D, Shen, Dong, Locke, Devin P, Wiechert, Madeline E, Eldred, James M, Peck, Josh B, Oberkfell, Benjamin J, Lolofie, Justin T, Du, Feiyu, Hawkins, Amy E, O’Laughlin, Michelle D, Bernard, Kelly E, Cunningham, Mark, Elliott, Glendoria, Mason, Mark D, Thompson Jr, Dominic M, Ivanovich, Jennifer L, Goodfellow, Paul J, Perou, Charles M, Weinstock, George M, Aft, Rebecca, Watson, Mark, Ley, Timothy J, Mardis, Elaine R

“…Massively parallel DNA sequencing technologies provide an unprecedented ability to screen entire genomes for genetic changes associated with tumour…”
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De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population by Kessler, Michael D., Loesch, Douglas P., Perry, James A., Heard-Costa, Nancy L., Taliun, Daniel, Cade, Brian E., Wang, Heming, Daya, Michelle, Ziniti, John, Datta, Soma, Celedón, Juan C., Soto-Quiros, Manuel E., Avila, Lydiana, Weiss, Scott T., Barnes, Kathleen, Redline, Susan S., Vasan, Ramachandran S., Johnson, Andrew D., Mathias, Rasika A., Hernandez, Ryan, Wilson, James G., Nickerson, Deborah A., Abecasis, Goncalo, Browning, Sharon R., Zöllne, Sebastian, O’Connell, Jeffrey R., Mitchell, Braxton D., O’Connor, Timothy D.

“…De novo mutations (DNMs), or mutations that appear in an individual despite not being seen in their parents, are an important source of genetic variation whose…”
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Models for Growth by Appelbaum, Elizabeth B.

“…Almost all calculus textbooks contain a specific model of exponential growth, with solution "y = y0ekx. A good exercise for students is to find what value of…”
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Author Correction: The landscape of viral associations in human cancers by Zapatka, Marc, Borozan, Ivan, Brewer, Daniel S., Iskar, Murat, Grundhoff, Adam, Alawi, Malik, Desai, Nikita, Sültmann, Holger, Moch, Holger, Cooper, Colin S., Eils, Roland, Ferretti, Vincent, Lichter, Peter

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Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers by Yuan, Yuan, Ju, Young Seok, Kim, Youngwook, Li, Jun, Wang, Yumeng, Yoon, Christopher J., Yang, Yang, Martincorena, Inigo, Creighton, Chad J., Weinstein, John N., Xu, Yanxun, Han, Leng, Kim, Hyung-Lae, Nakagawa, Hidewaki, Park, Keunchil, Campbell, Peter J., Liang, Han

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Author Correction: The evolutionary history of 2,658 cancers by Gerstung, Moritz, Jolly, Clemency, Leshchiner, Ignaty, Dentro, Stefan C., Gonzalez, Santiago, Rosebrock, Daniel, Mitchell, Thomas J., Rubanova, Yulia, Anur, Pavana, Yu, Kaixian, Tarabichi, Maxime, Deshwar, Amit, Wintersinger, Jeff, Kleinheinz, Kortine, Vázquez-García, Ignacio, Haase, Kerstin, Jerman, Lara, Sengupta, Subhajit, Macintyre, Geoff, Malikic, Salem, Donmez, Nilgun, Livitz, Dimitri G., Cmero, Marek, Demeulemeester, Jonas, Schumacher, Steven, Fan, Yu, Yao, Xiaotong, Lee, Juhee, Schlesner, Matthias, Boutros, Paul C., Bowtell, David D., Zhu, Hongtu, Getz, Gad, Imielinski, Marcin, Beroukhim, Rameen, Sahinalp, S. Cenk, Ji, Yuan, Peifer, Martin, Markowetz, Florian, Mustonen, Ville, Yuan, Ke, Wang, Wenyi, Morris, Quaid D., Spellman, Paul T., Wedge, David C., Van Loo, Peter

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Human whole-exome genotype data for Alzheimer’s disease by Leung, Yuk Yee, Naj, Adam C., Chou, Yi-Fan, Valladares, Otto, Schmidt, Michael, Hamilton-Nelson, Kara, Wheeler, Nicholas, Lin, Honghuang, Gangadharan, Prabhakaran, Qu, Liming, Clark, Kaylyn, Kuzma, Amanda B., Lee, Wan-Ping, Cantwell, Laura, Nicaretta, Heather, Haines, Jonathan, Farrer, Lindsay, Seshadri, Sudha, Brkanac, Zoran, Cruchaga, Carlos, Pericak-Vance, Margaret, Mayeux, Richard P., Bush, William S., Destefano, Anita, Martin, Eden, Schellenberg, Gerard D., Wang, Li-San

“…The heterogeneity of the whole-exome sequencing (WES) data generation methods present a challenge to a joint analysis. Here we present a bioinformatics…”
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A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease by Zhang, Xiaoling, Ma, Yiyi, Lancour, Daniel, Farrell, John J., Chung, Jaeyoon, Dinh, Huyen, Doddapeneni, Harsha, English, Adam, Gibbs, Richard A., Han, Yi, Jayaseelan, Joy, Kalra, Divya, Khan, Ziad, Lee, Sandra, Liu, Yue, Muzny, Donna, Nasser, Waleed, White, Simon, Worley, Kim, Zhu, Yiming, Beiser, Alexa, Chen, Yuning, Chung, Jaeyoon, Cupples, L. Adrienne, DeStefano, Anita, Dupuis, Josee, Farrell, John, Farrer, Lindsay, Lancour, Daniel, Lin, Honghuang, Sarnowski, Chloe, Zhang, Xiaoling, Choi, Seung Hoan, Gabriel, Stacey, Butkiewicz, Mariusz, Haines, Jonathan, Song, Yeunjoo, Barral, Sandra, Reitz, Christiane, Reyes, Dolly, Tosto, Giuseppe, Vardarajan, Badri, Amad, Shahzad, Amin, Najaf, Ikram, M. Afran, van Duijn, Cornelia, Vanderspek, Ashley, Schmidt, Helena, Goate, Alison, Marcora, Edoardo, Foroud, Tatiana, Feolo, Michael, Launer, Lenore J., Bennett, David A., Xia, Li Charlie, Beecham, Gary, Hamilton-Nelson, Kara, Jaworski, James, Martin, Eden, Pericak-Vance, Margaret, Rajabli, Farid, Schmidt, Michael, Cantwell, Laura, Childress, Micah, Chou, Yi-Fan, Cweibel, Rebecca, Leung, Yuk Yee, Lin, Han-Jen, Malamon, John, Naj, Adam, Valladares, Otto, Wang, Li-San, Wang, Weixin, Zhang, Nancy, Boerwinkle, Eric, Bressler, Jan, Fornage, Myriam, Jian, Xueqiu, Liu, Xiaoming, Blue, Elizabeth, Brown, Lisa, Day, Tyler, Dorschner, Michael, Horimoto, Andrea R., Nato, Alejandro Q., Navas, Pat, Nguyen, Hiep, Rice, Kenneth, Sohi, Harkirat, Thornton, Timothy, Tsuang, Debby, Cruchaga, Carlos, Fulton, Robert S., Koboldt, Daniel C., Larson, David E., Waligorski, Jason, Wilson, Richard K., Haines, Jonathan L., Pericak-Vance, Margaret A., Lunetta, Kathryn L.

“…The genetic architecture of Alzheimer's disease (AD) is only partially understood. We conducted an association study for AD using whole sequence data from 507…”
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Teaching Mathematics Online by Appelbaum, Elizabeth, Ingrassia, Steve, Langsdorf, Alison

“…The editors of the focus issue discuss the articles surrounding the topic Teaching Mathematics Online…”
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THE ALZHEIMER’S DISEASE SEQUENCING PROJECT (ADSP) DATA UPDATE 2018 by Kuzma, Amanda B., Faber, Kelley, Salerno, William J., Leung, Yuk Yee, Cantwell, Laura B., Gupta, Namrata, Fulton, Robert, Valladares, Otto, Vogel, Briana, Appelbaum, Elizabeth, Choi, Seung Hoan, Hamilton-Nelson, Kara L., Zhao, Yi, Muzny, Donna, Qu, Liming, Reyes-Dumeyer, Dolly, Waligorski, Jason, Farrell, John, Naj, Adam C., Bis, Joshua C., Destefano, Anita L., Seshadri, Sudha, Boerwinkle, Eric, Schellenberg, Gerard, Foroud, Tatiana M., Wang, Li-San

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P1‐149: THE ALZHEIMER'S DISEASE SEQUENCING PROJECT (ADSP) DATA UPDATE 2018 by Kuzma, Amanda B., Faber, Kelley, Salerno, William J., Leung, Yuk Yee, Cantwell, Laura B., Gupta, Namrata, Fulton, Robert, Valladares, Otto, Vogel, Briana, Appelbaum, Elizabeth, Choi, Seung Hoan, Hamilton-Nelson, Kara L., Zhao, Yi, Muzny, Donna, Qu, Liming, Reyes-Dumeyer, Dolly, Waligorski, Jason, Farrell, John, Naj, Adam C., Bis, Joshua C., Destefano, Anita L., Seshadri, Sudha, Boerwinkle, Eric, Schellenberg, Gerard, Foroud, Tatiana M., Wang, Li-San

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Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages by Iglesia, Michael D., Jayasinghe, Reyka G., Chen, Siqi, Terekhanova, Nadezhda V., Herndon, John M., Storrs, Erik, Karpova, Alla, Zhou, Daniel Cui, Naser Al Deen, Nataly, Shinkle, Andrew T., Lu, Rita Jui-Hsien, Caravan, Wagma, Houston, Andrew, Zhao, Yanyan, Sato, Kazuhito, Lal, Preet, Street, Cherease, Martins Rodrigues, Fernanda, Southard-Smith, Austin N., Targino da Costa, André Luiz N., Zhu, Houxiang, Mo, Chia-Kuei, Crowson, Lisa, Fulton, Robert S., Wyczalkowski, Matthew A., Fronick, Catrina C., Fulton, Lucinda A., Sun, Hua, Davies, Sherri R., Appelbaum, Elizabeth L., Chasnoff, Sara E., Carmody, Madelyn, Brooks, Candace, Liu, Ruiyang, Wendl, Michael C., Oh, Clara, Bender, Diane, Cruchaga, Carlos, Harari, Oscar, Bredemeyer, Andrea, Lavine, Kory, Bose, Ron, Margenthaler, Julie, Held, Jason M., Achilefu, Samuel, Ademuyiwa, Foluso, Aft, Rebecca, Ma, Cynthia, Colditz, Graham A., Ju, Tao, Oh, Stephen T., Fitzpatrick, James, Hwang, E. Shelley, Shoghi, Kooresh I., Chheda, Milan G., Veis, Deborah J., Chen, Feng, Fields, Ryan C., Gillanders, William E., Ding, Li

“…Breast cancer (BC) is defined by distinct molecular subtypes with different cells of origin. The transcriptional networks that characterize the…”
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A SIMULATION TO MODEL EXPONENTIAL GROWTH by Appelbaum, Elizabeth Berman

“…Describes a simulation using dice-tossing students in a population cluster to model the growth of cancer cells. This growth is recorded in a scatterplot and…”
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THE ALZHEIMER’S DISEASE SEQUENCING PROJECT (ADSP) DATA UPDATE 2017 by Kuzma, Amanda B., Faber, Kelley, Salerno, William, Leung, Yuk Yee, Cantwell, Laura B., Feolo, Mike, Stine, Adam, Gupta, Namrata, Fulton, Robert, Valladares, Otto, Cweibel, Rebecca, Appelbaum, Elizabeth, Choi, Seung Hoan, Hamilton-Nelson, Kara L., Lin, Han-Jen, Muzny, Donna, Qu, Liming, Reyes-Dumeyer, Dolly, Waligorski, Jason, Farrell, John, Naj, Adam C., Bis, Joshua C., Destefano, Anita L., Seshadri, Sudha, Boerwinkle, Eric, Schellenberg, Gerard D., Foroud, Tatiana M., Wang, Li-San

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The characterization of the Phlebotomus papatasi transcriptome by Abrudan, J., Ramalho-Ortigão, M., O'Neil, S., Stayback, G., Wadsworth, M., Bernard, M., Shoue, D., Emrich, S., Lawyer, P., Kamhawi, S., Rowton, E. D., Lehane, M. J., Bates, P. A., Valenzeula, J. G., Tomlinson, C., Appelbaum, E., Moeller, D., Thiesing, B., Dillon, R., Clifton, S., Lobo, N. F., Wilson, R. K., Collins, F. H., McDowell, M. A.

“…As important vectors of human disease, phlebotomine sand flies are of global significance to human health, transmitting several emerging and re‐emerging…”
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Q. E. D by Appelbaum, Elizabeth

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Models for Growth by Appelbaum, Elizabeth B.

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