Search Results - "Aplenc, R."

Randomized trial of busulfan vs total body irradiation containing conditioning regimens for children with acute lymphoblastic leukemia: a Pediatric Blood and Marrow Transplant Consortium study by Bunin, N, Aplenc, R, Kamani, N, Shaw, K, Cnaan, A, Simms, S

“…Conditioning regimens for children with ALL have generally included total body irradiation (TBI), which may result in significant sequelae. The primary aim of…”
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Merging of the National Cancer Institute-funded cooperative oncology group data with an administrative data source to develop a more effective platform for clinical trial analysis and comparative effectiveness research: a report from the Children's Oncology Group by Aplenc, R., Fisher, B. T., Huang, Y. S., Li, Y., Alonzo, T. A., Gerbing, R. B., Hall, M., Bertoch, D., Keren, R., Seif, A. E., Sung, L., Adamson, P. C., Gamis, A.

“…ABSTRACT Purpose The National Cancer Institute–funded cooperative oncology group trials have improved overall survival for children with cancer from 10% to 85%…”
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Ethnic variation of TET2 SNP rs2454206 and association with clinical outcome in childhood AML: a report from the Children’s Oncology Group by Kutny, M A, Alonzo, T A, Gamazon, E R, Gerbing, R B, Geraghty, D, Lange, B, Heerema, N A, Sung, L, Aplenc, R, Franklin, J, Raimondi, S C, Hirsch, B A, Konkashbaev, A, Cox, N J, Onel, K, Gamis, A S, Meshinchi, S

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Pharmacogenetic determinants of outcome in acute lymphoblastic leukaemia by Aplenc, Richard, Lange, Beverly

“…Present day paediatric co-operative group acute lymphoblastic leukaemia (ALL) protocols cure approximately 80% of patients, a result achieved largely through…”
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Single nucleotide polymorphism in IL1B is associated with infection risk in paediatric acute myeloid leukaemia by Sung, L., Dix, D., Cellot, S., Gillmeister, B., Ethier, M.C., Roslin, N.M., Johnston, D.L., Feusner, J., Mitchell, D., Lewis, V., Aplenc, R., Yanofsky, R., Portwine, C., Price, V., Zelcer, S., Silva, M., Bowes, L., Michon, B., Stobart, K., Traubici, J., Allen, U., Beyene, J., den Hollander, N., Paterson, A.D.

“…We evaluated single nucleotide polymorphisms (SNPs) associated with infection risk in children with newly diagnosed acute myeloid leukaemia (AML). We conducted…”
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The role of the MTHFR 677C>T polymorphism in methotrexate-induced liver toxicity: a meta-analysis in patients with cancer by Hagleitner, M M, Coenen, M J H, Aplenc, R, Patiño-Garcia, A, Chiusolo, P, Gemmati, D, De Mattei, M, Ongaro, A, Krajinovic, M, Hoogerbrugge, P M, Vermeulen, S H H M, te Loo, D M W M

“…Methotrexate (MTX), one of the important pillars in the treatment of different forms of cancer, is associated with the development of hepatotoxicity. The…”
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Humanized chimeric antigen receptor (CAR)-modified T cells targeting CD19 induce remissions in children and young adults with relapsed/refractory lymphoblastic leukemia/lymphoma by Hucks, G.E, Barrett, D, Rheingold, S.R, Aplenc, R, Teachey, D.T, Callahan, C, Baniewicz, D, White, C, Talekar, M, Shaw, P, Brogdon, J.L, Young, R, Scholler, J, Marcucci, K, Chew, A, Levine, B.L, Frey, N, Porter, D, Lacey, S, Melenhorst, J, June, C, Grupp, S, Maude, S

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Platelet factor 4 platelet levels are inversely correlated with steady‐state platelet counts and with platelet transfusion needs in pediatric leukemia patients by LAMBERT, M. P., REZNIKOV, A., GRUBBS, A., NGUYEN, Y., XIAO, L., APLENC, R., RAUOVA, L., PONCZ, M.

“…To cite this article: Lambert MP, Reznikov A, Grubbs A, Nguyen Y, Xiao L, Aplenc R, Rauova L, Poncz M. Platelet factor 4 platelet levels are inversely…”
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Durable Remissions with Control of Cytokine Release Syndrome (CRS) Using T Cells Expressing CD19 Targeted Chimeric Antigen Receptor (CAR) CTL019 to Treat Relapsed/Refractory (R/R) Acute Lymphoid Leukemia (ALL) by Levine, B.L, Maude, S, Zheng, Z, Shaw, P, Ambrose, D, Aplenc, R, Barker, C, Barrett, D, Brogdon, J, Callahan, C, Chen, F, Chew, A, Suhoski Davis, M.M, Fesnak, A.D, Finklestein, J, Frey, N, Lacey, S, Lamontagne, A, Lewitt, L, Loew, A, Marcucci, K, Melenhorst, J, Motley, L, Mudambi, M, Nazimuddin, F, O'Rourke, M, Porter, D, Rheingold, S.R, Scholler, J, Tayor, C, White, C, Wood, P, Young, R, Teachey, D.T, June, C, Grupp, S

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General anesthesia versus deep sedation for children undergoing invasive procedures in oncologic clinic by S. Shah-Hosseini, Z. A. Fang, C. J. Bae, K. A. Harris, R. M. Chiavacci, R. Aplenc, A. F. Reilly, A. E. Kazak, S. D. Cook-Sather

“…Abstract Introduction Several successful general anesthetic and deep sedation techniques have been established for children under- going invasive oncologic…”
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An unexpectedly high incidence of Epstein-Barr virus lymphoproliferative disease after CD34+ selected autologous peripheral blood stem cell transplant in neuroblastoma by POWELL, J. L, BUNIN, N. J, CALLAHAN, C, APLENC, R, GRIFFIN, G, GRUPP, S. A

“…The risk of Epstein-Barr virus lymphoproliferative disease (EBV-LPD) increases with the use of highly immunosuppressive therapies. Allogeneic BMT, especially…”
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Hematopoietic colony-stimulating factor priming does not influence survival in acute myeloid leukemia: a meta-analysis of randomized trials by Sung, L, Alibhai, S M H, Beyene, J, Gamis, A, Almeida, R, Smith, S, Aplenc, R

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Unrelated donor bone marrow transplantation for children with severe aplastic anemia: minimal GVHD and durable engraftment with partial T cell depletion by BUNIN, N, APLENC, R, IANNONE, R, LEAHEY, A, GRUPP, S, MONOS, D, PIERSON, G

“…Both increased graft rejection and increased graft vs host disease (GVHD) remain obstacles to success for unrelated donor (URD) BMT for patients with SAA…”
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Differential bone marrow aspirate DNA yields from commercial extraction kits by Aplenc, R, Orudjev, E, Swoyer, J, Manke, B, Rebbeck, T

“…Leukemia (2002) 16, 1865-1866. doi:10.1038/sj.leu.2402681…”
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Unrelated donor or partially matched related donor peripheral stem cell transplant with CD34+ selection and CD3+ addback for pediatric patients with leukemias by BUNIN, N, APLENC, R, GRUPP, S, PIERSON, G, MONOS, D

“…Unmodified peripheral stem cell transplants are associated with an increased risk of extensive chronic GVHD. T depletion may reduce this risk, but the risk of…”
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Outcomes of transplantation with partial T-cell depletion of matched or mismatched unrelated or partially matched related donor bone marrow in children and adolescents with leukemias by BUNIN, N, APLENC, R, LEAHEY, A, MAGIRA, E, GRUPP, S, PIERSON, G, MONOS, D

“…Graft-versus-host disease (GVHD) remains a major barrier to successful hematopoietic stem cell transplant for patients who lack a matched related donor…”
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GST polymorphisms and occurrence of second neoplasms after treatment of childhood leukemia by Jazbec, J, Aplenc, R, Dolzan, V, Debeljak, M, Jereb, B

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Group Sequential Methods and Sample Size Savings in Biomarker-Disease Association Studies by Aplenc, R, Zhao, H, Rebbeck, T. R, Propert, K. J

“…Molecular epidemiological association studies use valuable biosamples and incur costs. Statistical methods for early genotyping termination may conserve…”
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(1033) - Comparing Outcomes and Resource Utilization Among Pediatric Heart Transplant Indications Using a Novel, Merged Data Set from the United Network for Organ Sharing and the Pediatric Health Information System (UNOS-PHIS) Databases by Burstein, D., Li, Y., Getz, K., Huang, Y., Rossano, J.W., O'Connor, M.J., Lin, K.Y., Aplenc, R.

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Functional polymorphisms in the transcription factor NRF2 in humans increase the risk of acute lung injury by Marzec, Jacqui M, Christie, Jason D, Reddy, Sekhar P, Jedlicka, Anne E, Vuong, Hue, Lanken, Paul N, Aplenc, Richard, Yamamoto, Tae, Yamamoto, Masayuki, Cho, Hye-Youn, Kleeberger, Steven R

“…We recently used positional cloning to identify the transcription factor Nrf2 (NF-E2 related factor 2) as a susceptibility gene in a murine model of…”
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