Search Results - "Apicco, Daniel J"

Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo by Apicco, Daniel J., Ash, Peter E. A., Maziuk, Brandon, LeBlang, Chelsey, Medalla, Maria, Al Abdullatif, Ali, Ferragud, Antonio, Botelho, Emily, Ballance, Heather I., Dhawan, Uma, Boudeau, Samantha, Cruz, Anna Lourdes, Kashy, Daniel, Wong, Aria, Goldberg, Lisa R., Yazdani, Neema, Zhang, Cheng, Ung, Choong Y., Tripodis, Yorghos, Kanaan, Nicholas M., Ikezu, Tsuneya, Cottone, Pietro, Leszyk, John, Li, Hu, Luebke, Jennifer, Bryant, Camron D., Wolozin, Benjamin

“…Emerging studies suggest a role for tau in regulating the biology of RNA binding proteins (RBPs). We now show that reducing the RBP T-cell intracellular…”
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Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity by Vanderweyde, Tara, Apicco, Daniel J., Youmans-Kidder, Katherine, Ash, Peter E.A., Cook, Casey, Lummertz da Rocha, Edroaldo, Jansen-West, Karen, Frame, Alissa A., Citro, Allison, Leszyk, John D., Ivanov, Pavel, Abisambra, Jose F., Steffen, Martin, Li, Hu, Petrucelli, Leonard, Wolozin, Benjamin

“…Dendritic mislocalization of microtubule associated protein tau is a hallmark of tauopathies, but the role of dendritic tau is unknown. We now report that tau…”
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Dysregulation of RNA Splicing in Tauopathies by Apicco, Daniel J., Zhang, Cheng, Maziuk, Brandon, Jiang, Lulu, Ballance, Heather I., Boudeau, Samantha, Ung, Choong, Li, Hu, Wolozin, Benjamin

“…Pathological aggregation of RNA binding proteins (RBPs) is associated with dysregulation of RNA splicing in PS19 P301S tau transgenic mice and in Alzheimer’s…”
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Pathological stress granules in Alzheimer’s disease by Ash, Peter E.A, Vanderweyde, Tara E, Youmans, Katherine L, Apicco, Daniel J, Wolozin, Benjamin

“…Abstract A feature of neurodegenerative disease is the accumulation of insoluble protein aggregates in the brain. In some conditions, including Amyotrophic…”
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RNA binding proteins co-localize with small tau inclusions in tauopathy by Maziuk, Brandon F, Apicco, Daniel J, Cruz, Anna Lourdes, Jiang, Lulu, Ash, Peter E A, da Rocha, Edroaldo Lummertz, Zhang, Cheng, Yu, Wai Haung, Leszyk, John, Abisambra, Jose F, Li, Hu, Wolozin, Benjamin

“…The development of insoluble, intracellular neurofibrillary tangles composed of the microtubule-associated protein tau is a defining feature of tauopathies,…”
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The Parkinson’s disease-associated gene ITPKB protects against α-synuclein aggregation by regulating ER-to-mitochondria calcium release by Apicco, Daniel J., Shlevkov, Evgeny, Nezich, Catherine L., Tran, David T., Guilmette, Edward, Nicholatos, Justin W., Bantle, Collin M., Chen, Yi, Glajch, Kelly E., Abraham, Neeta A., Dang, Lan T., Kaynor, G. Campbell, Tsai, Ellen A., Nguyen, Khanh-Dung H., Groot, Joost, Liu, YuTing, Weihofen, Andreas, Hurt, Jessica A., Runz, Heiko, Hirst, Warren D.

“…Inositol-1,4,5-triphosphate (IP₃) kinase B (ITPKB) is a ubiquitously expressed lipid kinase that inactivates IP₃, a secondary messenger that stimulates calcium…”
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A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and Mitochondrial Proteins by Ruan, Qiu T, Yazdani, Neema, Blum, Benjamin C, Beierle, Jacob A, Lin, Weiwei, Coelho, Michal A, Fultz, Elissa K, Healy, Aidan F, Shahin, John R, Kandola, Amarpreet K, Luttik, Kimberly P, Zheng, Karen, Smith, Nathaniel J, Cheung, Justin, Mortazavi, Farzad, Apicco, Daniel J, Ragu Varman, Durairaj, Ramamoorthy, Sammanda, Ash, Peter E A, Rosene, Douglas L, Emili, Andrew, Wolozin, Benjamin, Szumlinski, Karen K, Bryant, Camron D

“…Individual variation in the addiction liability of amphetamines has a heritable genetic component. We previously identified (heterogeneous nuclear…”
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BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain by Pourhaghighi, Reza, Ash, Peter E A, Phanse, Sadhna, Goebels, Florian, Hu, Lucas Z M, Chen, Siwei, Zhang, Yingying, Wierbowski, Shayne D, Boudeau, Samantha, Moutaoufik, Mohamed T, Malty, Ramy H, Malolepsza, Edyta, Tsafou, Kalliopi, Nathan, Aparna, Cromar, Graham, Guo, Hongbo, Abdullatif, Ali Al, Apicco, Daniel J, Becker, Lindsay A, Gitler, Aaron D, Pulst, Stefan M, Youssef, Ahmed, Hekman, Ryan, Havugimana, Pierre C, White, Carl A, Blum, Benjamin C, Ratti, Antonia, Bryant, Camron D, Parkinson, John, Lage, Kasper, Babu, Mohan, Yu, Haiyuan, Bader, Gary D, Wolozin, Benjamin, Emili, Andrew

“…Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying…”
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Changes in neuronal immunofluorescence in the C- versus N-terminal domains of hnRNP H following D1 dopamine receptor activation by Ruan, Qiu T., Yazdani, Neema, Beierle, Jacob A., Hixson, Kathryn M., Hokenson, Kristen E., Apicco, Daniel J., Luttik, Kimberly P., Zheng, Karen, Maziuk, Brandon F., Ash, Peter E.A., Szumlinski, Karen K., Russek, Shelley J., Wolozin, Benjamin, Bryant, Camron D.

“…•We examined immunofluorescence and localization of hnRNP H following dopamine receptor activation in primary rat cortical neurons.•Activation of D1 dopamine…”
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Evaluation of ABT-888 in the amelioration of α-synuclein fibril-induced neurodegeneration by Hastings, Lyndsay, Sokratian, Arpine, Apicco, Daniel J., Stanhope, Christina M., Smith, Lindsey, Hirst, Warren D., West, Andrew B., Kelly, Kaela

“…Abstract The accumulation of α-synuclein inclusions in vulnerable neuronal populations pathologically defines Lewy body diseases including Parkinson’s disease…”
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Interaction between microtubule-associated protein tau and RNA binding proteins stimulates tau misfolding and stress granule formation by Vanderweyde, Tara, Youmans-Kidder, Kathrerine, Apicco, Daniel J, Ash, Peter E.A, Cook, Casey, Petrucelli, Leonard, Wolozin, Benjamin

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O4‐12‐05: Interaction between microtubule‐associated protein tau and RNA binding proteins stimulates tau misfolding and stress granule formation by Vanderweyde, Tara, Youmans-Kidder, Kathrerine, Apicco, Daniel J., Ash, Peter E.A., Cook, Casey, Petrucelli, Leonard, Wolozin, Benjamin

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TAU-INDUCED NEURODEGENERATION IS MEDIATED BY RNA BINDING PROTEINS by Wolozin, Benjamin, Apicco, Daniel J., Zhang, Cheng, Ash, Peter E.A., Maziuk, Brandon, Al Abdullatif, Ali, Ballance, Heather, Goldberg, Lisa R., Yazdani, Neema, Ung, Choon, Kanaan, Nicholas M., Ikezu, Tsuneya, Bryant, Camron D., Li, Hu

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Emerging Roles for RNA Binding Proteins in the Pathogenesis of Alzheimer's Disease and Frontotemporal Dementia by Apicco, Daniel J

“…Abnormal aggregation of microtubule associated protein tau is the defining pathological hallmark of tauopathies, which include Alzheimer’s disease (AD) and…”
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