Search Results - "Aphale, Abhishek"

Erosive pustular dermatosis successfully treated with a novel silicone gel by Uva, Luís, Aphale, Abhishek N., Kehdy, Jessica, Benedetto, Anthony V.

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Global Gene Expression Analysis Reveals Evidence for Decreased Lipid Biosynthesis and Increased Innate Immunity in Uninvolved Psoriatic Skin by Gudjonsson, Johann E., Ding, Jun, Li, Xing, Nair, Rajan P., Tejasvi, Trilokraj, Qin, Zhaohui S., Ghosh, Debashis, Aphale, Abhishek, Gumucio, Deborah L., Voorhees, John J., Abecasis, Goncalo R., Elder, James T.

“…Psoriasis is a genetically determined inflammatory skin disease. Although the transition from uninvolved into lesional skin is accompanied by changes in the…”
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EGFR and IL-1 Signaling Synergistically Promote Keratinocyte Antimicrobial Defenses in a Differentiation-Dependent Manner by Johnston, Andrew, Gudjonsson, Johann E., Aphale, Abhishek, Guzman, Andrew M., Stoll, Stefan W., Elder, James T.

“…Ligands of the EGF family regulate autocrine keratinocyte proliferation, and IL-1 family cytokines orchestrate epithelial defense responses. Although members…”
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Heterogeneity of inflammatory and cytokine networks in chronic plaque psoriasis by Swindell, William R, Xing, Xianying, Stuart, Philip E, Chen, Cynthia S, Aphale, Abhishek, Nair, Rajan P, Voorhees, John J, Elder, James T, Johnston, Andrew, Gudjonsson, Johann E

“…The clinical features of psoriasis, characterized by sharply demarcated scaly erythematous plaques, are typically so distinctive that a diagnosis can easily be…”
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Androgen Receptor Acetylation Site Mutations Cause Trafficking Defects, Misfolding, and Aggregation Similar to Expanded Glutamine Tracts by Thomas, Monzy, Dadgar, Nahid, Aphale, Abhishek, Harrell, Jennifer M., Kunkel, Robin, Pratt, William B., Lieberman, Andrew P.

“…Kennedy's disease is a degenerative disorder of motor neurons caused by the expansion of a glutamine tract near the amino terminus of the androgen receptor…”
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Mechanisms of action of etanercept in psoriasis by Tan, Jennifer K, Aphale, Abhishek, Malaviya, Rama, Sun, Yvonne, Gottlieb, Alice B

“…Psoriasis is a chronic inflammatory disease of the skin affecting up to 2.5% of the world's population. The scaly, erythematous plaques characteristic of this…”
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Lack of Evidence for Activation of the Hedgehog Pathway in Psoriasis by Gudjonsson, Johann E., Aphale, Abhishek, Grachtchouk, Marina, Ding, Jun, Nair, Rajan P., Wang, Timothy, Voorhees, John J., Dlugosz, Andrzej A., Elder, James T.

“…Recent reports have suggested that the hedgehog (Hh) pathway is activated in lesional psoriatic skin, and that treatment with the Hh pathway antagonist…”
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Validation of contactless smartphone measurement application in clinical context of Mohs micrographic surgery patients by Vickers, Conor, Tupchong, Sarah, Aphale, Abhishek

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Surgical excision, Mohs micrographic surgery, external‐beam radiotherapy, or brachytherapy for indolent skin cancer: An international meta‐analysis of 58 studies with 21,000 patients by Lee, Charles T., Lehrer, Eric J., Aphale, Abhishek, Lango, Miriam, Galloway, Thomas J., Zaorsky, Nicholas G.

“…Background The objective of this study was to compare the cosmesis and recurrence rates of conventional excision (CE), Mohs micrographic surgery (MMS),…”
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Surgical Excision, Mohs Micrographic Surgery, External Beam Radiotherapy, or Brachytherapy for Indolent Skin Cancer: An International Meta-analysis of 58 Studies with 21,000 Patients by Lee, Charles T., Lehrer, Eric J., Aphale, Abhishek, Lango, Miriam N., Galloway, Thomas, Zaorsky, Nicholas G.

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P34 - Surgical Excision, Mohs Micrographic Surgery, External Beam Radiotherapy, or Brachytherapy for Indolent Skin Cancer: An International Meta-analysis of 58 Studies with 21,000 Patients by Lee, Charles T., Lehrer, Eric J., Aphale, Abhishek, Lango, Miriam N., Galloway, Thomas, Zaorsky, Nicholas G.

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Induction of IL-17+ T cell trafficking and development by IFN-gamma: mechanism and pathological relevance in psoriasis by Kryczek, Ilona, Bruce, Allen T, Gudjonsson, Johann E, Johnston, Andrew, Aphale, Abhishek, Vatan, Linhua, Szeliga, Wojciech, Wang, Yin, Liu, Yan, Welling, Theodore H, Elder, James T, Zou, Weiping

“…Th1 and Th17 T cells are often colocalized in pathological environments, yet Th1-derived IFN-gamma inhibits Th17 cell development in vitro. We explored the…”
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Intravenous immunoglobulin G use in patients with chronic inflammatory demyelinating polyneuropathy: An uncommon cause of drug‐induced discoid lupus erythematosus by Jennings, Tara, Ahmed, Sarah, Aphale, Abhishek, Lee, Jason, Valdes‐Rodriguez, Rodrigo

“…Drug‐induced chronic cutaneous lupus erythematosus, or drug‐induced discoid lupus erythematosus, is a rare cutaneous phenomenon. Various medications have been…”
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Pembrolizumab-induced bullous pemphigoid by Sun, Christina W., Grossman, Shoshana K., Aphale, Abhishek, Hsu, Sylvia

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Evidence for Altered Wnt Signaling in Psoriatic Skin by Gudjonsson, Johann E., Johnston, Andrew, Stoll, Stefan W., Riblett, Mary B., Xing, Xianying, Kochkodan, James J., Ding, Jun, Nair, Rajan P., Aphale, Abhishek, Voorhees, John J., Elder, James T.

“…The Wnt gene family encodes a set of highly conserved secreted signaling proteins that have major roles in embryogenesis and tissue homeostasis. Yet the…”
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Transcriptional determinants of individualized inflammatory responses at anatomically separate sites by Tsoi, Lam C., Yang, Jingjing, Liang, Yun, Sarkar, Mrinal K., Xing, Xianying, Beamer, Maria A., Aphale, Abhishek, Raja, Kalpana, Kozlow, Jeffrey H., Getsios, Spiro, Voorhees, John J., Kahlenberg, J. Michelle, Elder, James T., Gudjonsson, Johann E.

“…[...]lincRNAs displayed significantly (P < 1 x 10−16) higher coefficient of variation for both between- and within-individual variabilities, and the contrast…”
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Differential Expression of Phosphorylated NF-κB/RelA in Normal and Psoriatic Epidermis and Downregulation of NF-κB in Response to Treatment with Etanercept by Lizzul, Paul F., Aphale, Abhishek, Malaviya, Rama, Sun, Yvonne, Masud, Salman, Dombrovskiy, Viktor, Gottlieb, Alice B.

“…Etanercept, a recombinant human tumor necrosis factor (TNF) receptor fusion protein, is FDA approved for psoriasis and psoriatic arthritis. TNFα increases the…”
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Differential expression of phosphorylated NF-kappaB/RelA in normal and psoriatic epidermis and downregulation of NF-kappaB in response to treatment with etanercept by Lizzul, Paul F, Aphale, Abhishek, Malaviya, Rama, Sun, Yvonne, Masud, Salman, Dombrovskiy, Viktor, Gottlieb, Alice B

“…Etanercept, a recombinant human tumor necrosis factor (TNF) receptor fusion protein, is FDA approved for psoriasis and psoriatic arthritis. TNFalpha increases…”
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Pembrolizumab-induced bullous pemphigoid by Sun, Christina W, Grossman, Shoshana K, Aphale, Abhishek, Hsu, Sylvia

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Intravenous immunoglobulin G use in patients with chronic inflammatory demyelinating polyneuropathy: An uncommon cause of drug-induced discoid lupus erythematosus by Jennings, Tara, Ahmed, Sarah, Aphale, Abhishek, Lee, Jason, Valdes-Rodriguez, Rodrigo

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