Search Results - "Apfel, Stuart"

Effects of Alcohol Administered With Flibanserin in Healthy Premenopausal Women: A Randomized, Double-Blind, Single-Dose Crossover Study by Simon, James A., Clayton, Anita H., Parish, Sharon J., Apfel, Stuart C., Millheiser, Leah

“…Flibanserin is approved in the United States and Canada for the treatment of hypoactive sexual desire disorder in premenopausal women. The purpose of this…”
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Nerve growth factor for the treatment of diabetic neuropathy: what went wrong, what went right, and what does the future hold? by Apfel, Stuart C

“…Since their discovery in the 1950s, neurotrophic factors have raised expectations that their clinical application to neurodegenerative diseases might provide…”
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Effect of Flibanserin Treatment on Body Weight in Premenopausal and Postmenopausal Women with Hypoactive Sexual Desire Disorder: A Post Hoc Analysis by Kornstein, Susan G, Simon, James A, Apfel, Stuart C, Yuan, James, Barbour, Krista A, Kissling, Robert

“…Flibanserin, a 5-HT agonist and 5-HT antagonist, is indicated for the treatment of acquired, generalized hypoactive sexual desire disorder (HSDD) in…”
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Botulinum toxin for neuropathic pain? by Apfel, Stuart C

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Efficacy and Safety of Recombinant Human Nerve Growth Factor in Patients With Diabetic Polyneuropathy: A Randomized Controlled Trial by Apfel, Stuart C, Schwartz, Sherwin, Adornato, Bruce T, Freeman, Roy, Biton, Victor, Rendell, Marc, Vinik, Aaron, Giuliani, Michael, Stevens, J. Clarke, Barbano, Richard, Dyck, Peter J, for the rhNGF Clinical Investigator Group

“…CONTEXT Nerve growth factor is a neurotrophic factor that promotes the survival of small fiber sensory neurons and sympathetic neurons in the peripheral…”
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Neurotrophic factors in the therapy of diabetic neuropathy by Apfel, S C

“…A large number of neurotrophic factors that exert effects on specific neuronal populations in the peripheral nervous system have been discovered. Some of these…”
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Is the therapeutic application of neurotrophic factors dead? by Apfel, Stuart C.

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Neurotrophic factor therapy--prospects and problems by Apfel, S C

“…Over the past 15 years neurotrophic factors have generated considerable excitement for their potential as therapy for a wide variety of degenerative…”
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Neurotrophic Factors and Pain by Apfel, Stuart C

“…Neurotrophic factors have been shown to play significant roles in the transmission of physiologic and pathologic pain. Nerve growth factor appears to be…”
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Thalidomide neuropathy: too much or too long? by Apfel, Stuart C, Zochodne, Douglas W

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Neurotrophic factors and diabetic peripheral neuropathy by Apfel, S C

“…Recent evidence from animal models of diabetes and human diabetic subjects suggests that the reduced availability of neurotrophic factors may contribute to the…”
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Nerve growth factor administration protects against experimental diabetic sensory neuropathy by Apfel, S C, Arezzo, J C, Brownlee, M, Federoff, H, Kessler, J A

“…Small fiber sensory neuropathy is one of the most common complications of diabetes mellitus. Currently there is no adequate therapy to prevent this often…”
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Nerve Growth Factor Regulates the Expression of Brain-Derived Neurotrophic Factor mRNA in the Peripheral Nervous System by Apfel, Stuart C., Wright, Douglas E., Wiideman, Andrea M., Dormia, Christine, Snider, William D., Kessler, John A.

“…Neurotrophins are profound regulators of neuronal survival in the developing peripheral nervous system and are synthesized by peripheral neurons themselves…”
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Effects of Alcohol Administered with Flibanserin in Healthy Premenopausal Women: A Randomized, Double-Blind, Single-Dose Crossover Study by Simon, James A., Clayton, Anita H., Parish, Sharon J., Apfel, Stuart C., Millheiser, Leah

“…Abstract Introduction Flibanserin is approved in the United States and Canada for the treatment of hypoactive sexual desire disorder in premenopausal women…”
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MP47-14 SELF-REPORTED ALCOHOL USE AND HYPOTENSION-AND-SYNCOPE-RELATED ADVERSE EVENTS IN FLIBANSERIN-TREATED PREMENOPAUSAL WOMEN WITH HYPOACTIVE SEXUAL DESIRE DISORDER by Apfel, Stuart, Brown, Louise, Yuan, James, Spigelman, Sam

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Insulin-like growth factor-I prevents development of a vincristine neuropathy in mice by Contreras, Patricia C, Vaught, Jeffry L, Gruner, John A, Brosnan, Celia, Steffler, Cathy, Arezzo, Joseph C, Lewis, Michael E, Kessler, John A, Apfel, Stuart C

“…Vincristine is a commonly used antitumor agent whose major dose-limiting side-effect is a mixed sensorimotor neuropathy. To assess whether insulin-like growth…”
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Pooled safety analysis of high-specific-activity I-131 MIBG in iobenguane scan positive cancer patients by Jimenez, Camilo, Grewal, Ravinder K., Ravizzini, Gregory, Chin, Bennett B, Pampaloni, Miguel H, Matthay, Katherine K., Jensen, Jessica Donato, Lin, Tess, Apfel, Stuart, White, Theresa, Stambler, Nancy, DiPippo, Vincent A., Mahmood, Syed, Wong, Vivien, Pryma, Daniel

“…Abstract only 388 Background: Iobenguane scan positive cancers include pheochromocytoma and paraganglioma (PPGL), neuroblastoma, and gastroenteropancreatic…”
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Nerve growth factor prevents toxic neuropathy in mice by Apfel, S C, Lipton, R B, Arezzo, J C, Kessler, J A

“…Taxol is a promising new antitumor drug with therapeutic use that is limited by a toxic sensory neuropathy. Taxol is also cytotoxic to dorsal root ganglion…”
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Efficacy and Safety of High-Specific-Activity 131I-MIBG Therapy in Patients with Advanced Pheochromocytoma or Paraganglioma by Pryma, Daniel A, Chin, Bennett B, Noto, Richard B, Dillon, Joseph S, Perkins, Stephanie, Solnes, Lilja, Kostakoglu, Lale, Serafini, Aldo N, Pampaloni, Miguel H, Jensen, Jessica, Armor, Thomas, Lin, Tess, White, Theresa, Stambler, Nancy, Apfel, Stuart, DiPippo, Vincent A, Mahmood, Syed, Wong, Vivien, Jimenez, Camilo

“…Patients with metastatic or unresectable (advanced) pheochromocytoma and paraganglioma (PPGL) have poor prognoses and few treatment options. This multicenter,…”
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Efficacy and Safety of High-Specific-Activity 131 I-MIBG Therapy in Patients with Advanced Pheochromocytoma or Paraganglioma by Pryma, Daniel A, Chin, Bennett B, Noto, Richard B, Dillon, Joseph S, Perkins, Stephanie, Solnes, Lilja, Kostakoglu, Lale, Serafini, Aldo N, Pampaloni, Miguel H, Jensen, Jessica, Armor, Thomas, Lin, Tess, White, Theresa, Stambler, Nancy, Apfel, Stuart, DiPippo, Vincent A, Mahmood, Syed, Wong, Vivien, Jimenez, Camilo

“…Patients with metastatic or unresectable (advanced) pheochromocytoma and paraganglioma (PPGL) have poor prognoses and few treatment options. This multicenter,…”
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