Search Results - "Aparicio‐Soto, Marina"

Unique and common TCR repertoire features of Ni2+‐, Co2+‐, and Pd2+‐specific human CD154 + CD4+ T cells by Riedel, Franziska, Aparicio‐Soto, Marina, Curato, Caterina, Münch, Lucas, Abbas, Amro, Thierse, Hermann‐Josef, Peitsch, Wiebke K., Luch, Andreas, Siewert, Katherina

“…Background Apart from Ni2+, Co2+, and Pd2+ ions commonly trigger T cell‐mediated allergic contact dermatitis. However, in vitro frequencies of metal‐specific T…”
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TCRs with segment TRAV9‐2 or a CDR3 histidine are overrepresented among nickel‐specific CD4+ T cells by Aparicio‐Soto, Marina, Riedel, Franziska, Leddermann, Melanie, Bacher, Petra, Scheffold, Alexander, Kuhl, Heiner, Timmermann, Bernd, Chudakov, Dmitriy M., Molin, Sonja, Worm, Margitta, Heine, Guido, Thierse, Hermann‐Josef, Luch, Andreas, Siewert, Katherina

“…Background Nickel is the most frequent cause of T cell–mediated allergic contact dermatitis worldwide. In vitro, CD4+ T cells from all donors respond to nickel…”
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Olive‐Oil‐Derived Polyphenols Effectively Attenuate Inflammatory Responses of Human Keratinocytes by Interfering with the NF‐κB Pathway by Aparicio‐Soto, Marina, Redhu, Davender, Sánchez‐Hidalgo, Marina, Fernández‐Bolaños, José G., Alarcón‐de‐la‐Lastra, Catalina, Worm, Margitta, Babina, Magda

“…Scope Extra virgin olive oil (EVOO) is rich in phenolic compounds, including hydroxytyrosol (HTy) and hydroxytyrosyl acetate (HTy‐Ac), which have presented…”
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Dietary squalene supplementation improves DSS‐induced acute colitis by downregulating p38 MAPK and NFkB signaling pathways by Sánchez‐Fidalgo, Susana, Villegas, Isabel, Rosillo, Maria Ángeles, Aparicio‐Soto, Marina, de la Lastra, Catalina Alarcón

“…SCOPE: Squalene is a polyunsaturated triterpene, which has exhibited anticancer and antioxidant activities among others. We investigated dietary squalene…”
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Unique and common TCR repertoire features of Ni 2+ -, Co 2+ -, and Pd 2+ -specific human CD154 + CD4+ T cells by Riedel, Franziska, Aparicio-Soto, Marina, Curato, Caterina, Münch, Lucas, Abbas, Amro, Thierse, Hermann-Josef, Peitsch, Wiebke K, Luch, Andreas, Siewert, Katherina

“…Apart from Ni , Co , and Pd ions commonly trigger T cell-mediated allergic contact dermatitis. However, in vitro frequencies of metal-specific T cells and the…”
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Immunological Mechanisms of Metal Allergies and the Nickel-Specific TCR-pMHC Interface by Riedel, Franziska, Aparicio-Soto, Marina, Curato, Caterina, Thierse, Hermann-Josef, Siewert, Katherina, Luch, Andreas

“…Besides having physiological functions and general toxic effects, many metal ions can cause allergic reactions in humans. We here review the immune events…”
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Dietary extra virgin olive oil polyphenols supplementation modulates DSS-induced chronic colitis in mice by Sánchez-Fidalgo, Susana, Cárdeno, Ana, Sánchez-Hidalgo, Marina, Aparicio-Soto, Marina, de la Lastra, Catalina Alarcón

“…We evaluated the protective effect of dietary extra virgin olive oil (EVOO) polyphenol extract (PE) supplementation in the inflammatory response associated to…”
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Dietary extra-virgin olive oil prevents inflammatory response and cartilage matrix degradation in murine collagen-induced arthritis by Rosillo, María Angeles, Sánchez-Hidalgo, Marina, Sánchez-Fidalgo, Susana, Aparicio-Soto, Marina, Villegas, Isabel, Alarcón-de-la-Lastra, Catalina

“…PURPOSE: Current experimental studies support a beneficial role of extra-virgin olive oil (EVOO) in several inflammatory diseases. The present study was…”
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Squalene targets pro- and anti-inflammatory mediators and pathways to modulate over-activation of neutrophils, monocytes and macrophages by Cárdeno, Ana, Aparicio-Soto, Marina, Montserrat-de la Paz, Sergio, Bermudez, Beatriz, Muriana, Francisco J.G., Alarcón-de-la-Lastra, Catalina

“…•Squalene has anti-inflammatory activities on LPS-mediated inflammatory response.•Squalene targets pro-inflammatory mediators such as TLR4, iNOS, COX-2 or…”
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Extra virgin olive oil: a key functional food for prevention of immune-inflammatory diseases by Aparicio-Soto, Marina, Sánchez-Hidalgo, Marina, Rosillo, Ma Ángeles, Castejón, Ma Luisa, Alarcón-de-la-Lastra, Catalina

“…Nowadays, it is clear that an unhealthy diet is one of the prime factors that contributes to the rise of inflammatory diseases and autoimmunity in the…”
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Olive secoiridoid oleuropein and its semisynthetic acetyl-derivatives reduce LPS-induced inflammatory response in murine peritoneal macrophages via JAK-STAT and MAPKs signaling pathways by Castejon, Maria Luisa, Sánchez-Hidalgo, Marina, Aparicio-Soto, Marina, González-Benjumea, Alejandro, Fernández-Bolaños, Jose G., Alarcón-de-la-Lastra, Catalina

“…[Display omitted] •OL and new derivatives exert antiinflammatory effect in LPS-stimulated macrophages.•These compounds inhibit LPS-induced NO2−…”
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The phenolic fraction of extra virgin olive oil modulates the activation and the inflammatory response of T cells from patients with systemic lupus erythematosus and healthy donors by Aparicio‐Soto, Marina, Sánchéz‐Hidalgo, Marina, Cárdeno, Ana, Lucena, Jose Manuel, Gonzáléz‐Escribano, Francisca, Castillo, Maria Jesus, Alarcón‐de‐la‐Lastra, Catalina

“…Scope Systemic lupus erythematosus (SLE) is a chronic multiorgan autoimmune disease characterized by immune deregulation, which involves altered T‐cell…”
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In Vitro Monitoring of Human T Cell Responses to Skin Sensitizing Chemicals-A Systematic Review by Aparicio-Soto, Marina, Curato, Caterina, Riedel, Franziska, Thierse, Hermann-Josef, Luch, Andreas, Siewert, Katherina

“…Chemical allergies are T cell-mediated diseases that often manifest in the skin as allergic contact dermatitis (ACD). To prevent ACD on a public health scale…”
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Dietary hydroxytyrosol and hydroxytyrosyl acetate supplementation prevent pristane-induced systemic lupus erythematous in mice by Aparicio-Soto, Marina, Sánchez-Hidalgo, Marina, Cárdeno, Ana, González-Benjumea, Alejandro, Fernández-Bolaños, José G., Alarcón-de-la-Lastra, Catalina

“…•Dietary phenols may have beneficial roles on immuno-inflammatory diseases like SLE.•We evaluate the effects of two phenol supplemented diets on a SLE mice…”
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Frequencies and TCR Repertoires of Human 2,4,6-Trinitrobenzenesulfonic Acid-specific T Cells by Curato, Caterina, Aparicio-Soto, Marina, Riedel, Franziska, Wehl, Ingrun, Basaran, Alev, Abbas, Amro, Thierse, Hermann-Josef, Luch, Andreas, Siewert, Katherina

“…Allergic contact dermatitis is a widespread T cell-mediated inflammatory skin disease, but monitoring of chemical-specific T cells remains challenging. We here…”
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Mast cells instruct keratinocytes to produce thymic stromal lymphopoietin: Relevance of the tryptase/protease-activated receptor 2 axis by Redhu, Davender, Franke, Kristin, Aparicio-Soto, Marina, Kumari, Vandana, Pazur, Kristijan, Illerhaus, Anja, Hartmann, Karin, Worm, Margitta, Babina, Magda

“…Thymic stromal lymphopoietin (TSLP) promotes TH2 inflammation and is deeply intertwined with inflammatory dermatoses like atopic dermatitis. The mechanisms…”
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An update on diet and nutritional factors in systemic lupus erythematosus management by Aparicio-Soto, Marina, Sánchez-Hidalgo, Marina, Alarcón-de-la-Lastra, Catalina

“…Systemic lupus erythematosus (SLE) is a chronic inflammatory and autoimmune disease characterised by multiple organ involvement and a large number of…”
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Chemical-Specific T Cell Tests Aim to Bridge a Gap in Skin Sensitization Evaluation by Fritsch, Nele, Aparicio-Soto, Marina, Curato, Caterina, Riedel, Franziska, Thierse, Hermann-Josef, Luch, Andreas, Siewert, Katherina

“…T cell activation is the final key event (KE4) in the adverse outcome pathway (AOP) of skin sensitization. However, validated new approach methodologies (NAMs)…”
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Virgin olive oil and its phenol fraction modulate monocyte/macrophage functionality: a potential therapeutic strategy in the treatment of systemic lupus erythematosus by Aparicio-Soto, Marina, Montserrat-de la Paz, Sergio, Sanchez-Hidalgo, Marina, Cardeno, Ana, Bermudez, Beatriz, Muriana, Francisco J. G., Alarcon-de-la-Lastra, Catalina

“…Monocytes and macrophages are critical effectors and regulators of inflammation and innate immune response, which appear altered in different autoimmune…”
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Dietary supplementation of an ellagic acid-enriched pomegranate extract attenuates chronic colonic inflammation in rats by Rosillo, Maria Angeles, Sánchez-Hidalgo, Marina, Cárdeno, Ana, Aparicio-Soto, Marina, Sánchez-Fidalgo, Susana, Villegas, Isabel, de la Lastra, Catalina Alarcón

“…Dietary polyphenols present in Punica granatum (pomegranate), such as ellagitannins and ellagic acid (EA) have shown to exert anti-inflammatory and antioxidant…”
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