Search Results - "Aparicio, Guillermo"

Biomonitoring and precision health in deep space supported by artificial intelligence by Scott, Ryan T., Sanders, Lauren M., Antonsen, Erik L., Hastings, Jaden J. A., Park, Seung-min, Mackintosh, Graham, Reynolds, Robert J., Hoarfrost, Adrienne L., Sawyer, Aenor, Greene, Casey S., Glicksberg, Benjamin S., Theriot, Corey A., Berrios, Daniel C., Miller, Jack, Babdor, Joel, Barker, Richard, Baranzini, Sergio E., Beheshti, Afshin, Chalk, Stuart, Delgado-Aparicio, Guillermo M., Haendel, Melissa, Hamid, Arif A., Heller, Philip, Jamieson, Daniel, Jarvis, Katelyn J., Kalantari, John, Khezeli, Kia, Komarova, Svetlana V., Komorowski, Matthieu, Kothiyal, Prachi, Mahabal, Ashish, Manor, Uri, Garcia Martin, Hector, Mason, Christopher E., Matar, Mona, Mias, George I., Myers, Jerry G., Nelson, Charlotte, Oribello, Jonathan, Parsons-Wingerter, Patricia, Prabhu, R. K., Qutub, Amina Ann, Rask, Jon, Saravia-Butler, Amanda, Saria, Suchi, Singh, Nitin Kumar, Snyder, Michael, Soboczenski, Frank, Soman, Karthik, Van Valen, David, Venkateswaran, Kasthuri, Warren, Liz, Worthey, Liz, Yang, Jason H., Zitnik, Marinka, Costes, Sylvain V.

“…Human exploration of deep space will involve missions of substantial distance and duration. To effectively mitigate health hazards, paradigm shifts in…”
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Biological research and self-driving labs in deep space supported by artificial intelligence by Sanders, Lauren M., Scott, Ryan T., Yang, Jason H., Qutub, Amina Ann, Garcia Martin, Hector, Berrios, Daniel C., Hastings, Jaden J. A., Rask, Jon, Mackintosh, Graham, Hoarfrost, Adrienne L., Chalk, Stuart, Kalantari, John, Khezeli, Kia, Antonsen, Erik L., Babdor, Joel, Barker, Richard, Baranzini, Sergio E., Beheshti, Afshin, Delgado-Aparicio, Guillermo M., Glicksberg, Benjamin S., Greene, Casey S., Haendel, Melissa, Hamid, Arif A., Heller, Philip, Jamieson, Daniel, Jarvis, Katelyn J., Komarova, Svetlana V., Komorowski, Matthieu, Kothiyal, Prachi, Mahabal, Ashish, Manor, Uri, Mason, Christopher E., Matar, Mona, Mias, George I., Miller, Jack, Myers, Jerry G., Nelson, Charlotte, Oribello, Jonathan, Park, Seung-min, Parsons-Wingerter, Patricia, Prabhu, R. K., Reynolds, Robert J., Saravia-Butler, Amanda, Saria, Suchi, Sawyer, Aenor, Singh, Nitin Kumar, Snyder, Michael, Soboczenski, Frank, Soman, Karthik, Theriot, Corey A., Van Valen, David, Venkateswaran, Kasthuri, Warren, Liz, Worthey, Liz, Zitnik, Marinka, Costes, Sylvain V.

“…Space biology research aims to understand fundamental spaceflight effects on organisms, develop foundational knowledge to support deep space exploration and,…”
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Preventive and therapeutic effects of JM-20 on paclitaxel-evoked painful peripheral neuropathy in rats by Bárbara B. Garrido-Suárez, Gabino Garrido, Addis Bellma Menéndez, Guillermo Aparicio, Odalys Valdés, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes, René Delgado-Hernández

“…Context: JM-20 is a hybrid synthetic molecule, which is based on a multimodal drug design paradigm for cerebrovascular disease. In addition to its…”
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Morphometric alterations of Golgi apparatus in Alzheimer's disease are related to tau hyperphosphorylation by Antón-Fernández, Alejandro, Aparicio-Torres, Guillermo, Tapia, Silvia, DeFelipe, Javier, Muñoz, Alberto

“…Abstract The Golgi apparatus (GA) is a highly dynamic organelle, which is mainly involved in the post-translational processing and targeting of cellular…”
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JM-20 protects memory acquisition and consolidation on scopolamine model of cognitive impairment by Wong-Guerra, Maylin, Jiménez-Martin, Javier, Fonseca-Fonseca, Luis Arturo, Ramírez-Sánchez, Jeney, Montano-Peguero, Yanay, Rocha, Joao Batista, D´Avila, Fernanda, de Assis, Adriano M., Souza, Diogo Onofre, Pardo-Andreu, Gilberto L., del Valle, Roberto Menéndez-Soto, Lopez, Guillermo Aparicio, Martínez, Odalys Valdés, García, Nelson Merino, Mondelo-Rodríguez, Abel, Padrón-Yaquis, Alejandro Saúl, Nuñez-Figueredo, Yanier

“…Objective: JM-20, a novel hybrid synthetic molecule, has been reported to have antioxidant, mitoprotective, anti-excitotoxic, anti-apoptotic and…”
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Therapeutic potential of the novel hybrid molecule JM-20 against focal cortical ischemia in rats by Yanier Núñez Figueredo, Jeney Ramírez-Sanchez, Gisele Hansel, Gilberto L. Pardo-Andreu, Nelson Merino, Guillermo Aparicio, Rene Delgado-Hernández, Laura García-Pupo, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes, Diogo O. Souza

“…Context: Despite the great mortality and morbidity of stroke, treatment options remain limited. We previously showed that JM-20, a novel synthetic molecule,…”
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A multi-target ligand (JM-20) prevents morphine-induced hyperalgesia in naïve and neuropathic rats by Garrido-Suárez, Bárbara B., Garrido, Gabino, Bellma-Menéndez, Addis, Aparicio-López, Guillermo, Valdés-Martínez, Odalys, Morales-Aguiar, Ruth A., Fernández-Pérez, Miguel D., Ochoa-Rodríguez, Estael, Verdecia-Reyes, Yamila, Delgado-Hernández, René

“…The present study examines the possible inhibitory effect of JM-20, a multi-target neuroprotective compound, on the development of morphine-induced…”
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Quantitative analysis of the GABAergic innervation of the soma and axon initial segment of pyramidal cells in the human and mouse neocortex by Ostos, Sandra, Aparicio, Guillermo, Fernaud-Espinosa, Isabel, DeFelipe, Javier, Muñoz, Alberto

“…Abstract Perisomatic GABAergic innervation in the cerebral cortex is carried out mostly by basket and chandelier cells, which differentially participate in the…”
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Xanthium strumarium´s xanthatins induces mitotic arrest and apoptosis in CT26WT colon carcinoma cells by Piloto-Ferrer, Janet, Sánchez-Lamar, Ángel, Francisco, Marbelis, González, Maria L., Merino, Nelsón, Aparicio, Guillermo, Pérez, Carlos, Rodeiro, Idania, Lopes, Miriam Teresa Paz

“…Colorectal cancer is one of the most common malignancies worldwide and is associated with high mortality rates. We previously reported that Xanthium strumarium…”
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Síndrome Hepatopulmonar, un diagnóstico olvidado. Informe de caso by Sosa Ferrari, Suyapa, Zaldivar Aparicio, Guillermo

“…Antecedentes: El síndrome hepatopulmonar (SHP) se presenta en pacientes con cirrosis hepática con una prevalencia variante según diferentes estudios,…”
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Safety evaluation of chitosan and chitosan acid salts from Panurilus argus lobster by Lagarto, Alicia, Merino, Nelson, Valdes, Odalys, Dominguez, Jesus, Spencer, Evelyn, de la Paz, Nilia, Aparicio, Guillermo

“…Chitosan is a natural polymer with excellent properties such as biocompatibility, biodegradability, non-toxicity and adsorptive abilities. We obtained chitosan…”
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RELATIONSHIP BETWEEN PHOSPHO-TAU ACCUMULATION AND STRUCTURAL ALTERATIONS OF NEURONAL GOLGI APPARATUS IN ALZHEIMER’S DISEASE PATIENTS AND P301S TAUOPATHY MOUSE MODEL by Fernandez, Alejandro Anton, Torres, Guillermo Aparicio, Rubira, Jesús Merchan, Gonzalez, Silvia Tapia, Defelipe, Javier, Avila, Jesus, Hernandez, Félix, Muñoz, Alberto

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Preventive and therapeutic effects of JM-20 on paclitaxel-evoked painful peripheral neuropathy in rats by Garrido-Suárez, Bárbara B., Garrido, Gabino, Bellma Menéndez, Addis, Aparicio, Guillermo, Valdés, Odalys, Ochoa-Rodríguez, Estael, Verdecia-Reyes, Yamila, Delgado-Hernández, René

“…Context: JM-20 is a hybrid synthetic molecule, which is based on a multimodal drug design paradigm for cerebrovascular disease. In addition to its…”
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Defining metric-aware size-shape measures to validate and optimize curved high-order meshes by Aparicio-Estrems, Guillermo, Gargallo-Peiró, Abel, Roca, Xevi

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Combining High-Order Metric Interpolation and Geometry Implicitization for Curved r-Adaption by Aparicio-Estrems, Guillermo, Gargallo-Peiró, Abel, Roca, Xevi

“…We detail how to use Newton’s method for distortion-based curved r-adaption to a discrete high-order metric field while matching a target geometry…”
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A Globalized and Preconditioned Newton-CG Solver for Metric-Aware Curved High-Order Mesh Optimization by Aparicio-Estrems, Guillermo, Gargallo-Peiró, Abel, Roca, Xevi

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Therapeutic potential of the novel hybrid molecule JM-20 against focal cortical ischemia in rats by Núñez Figueredo, Yanier, Ramírez-Sanchez, Jeney, Hansel, Gisele, Pardo-Andreu, Gilberto L., Merino, Nelson, Aparicio, Guillermo, Delgado-Hernández, Rene, García-Pupo, Laura, Ochoa-Rodríguez, Estael, Verdecia-Reyes, Yamila, Souza, Diogo O.

“…Context: Despite the great mortality and morbidity of stroke, treatment options remain limited. We previously showed that JM-20, a novel synthetic molecule,…”
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Beyond Low Earth Orbit: Biological Research, Artificial Intelligence, and Self-Driving Labs by Sanders, Lauren M, Yang, Jason H, Scott, Ryan T, Qutub, Amina Ann, Martin, Hector Garcia, Berrios, Daniel C, Hastings, Jaden J. A, Rask, Jon, Mackintosh, Graham, Hoarfrost, Adrienne L, Chalk, Stuart, Kalantari, John, Khezeli, Kia, Antonsen, Erik L, Babdor, Joel, Barker, Richard, Baranzini, Sergio E, Beheshti, Afshin, Delgado-Aparicio, Guillermo M, Glicksberg, Benjamin S, Greene, Casey S, Haendel, Melissa, Hamid, Arif A, Heller, Philip, Jamieson, Daniel, Jarvis, Katelyn J, Komarova, Svetlana V, Komorowski, Matthieu, Kothiyal, Prachi, Mahabal, Ashish, Manor, Uri, Mason, Christopher E, Matar, Mona, Mias, George I, Miller, Jack, MyersJr, Jerry G, Nelson, Charlotte, Oribello, Jonathan, Park, Seung-min, Parsons-Wingerter, Patricia, Prabhu, R. K, Reynolds, Robert J, Saravia-Butler, Amanda, Saria, Suchi, Sawyer, Aenor, Singh, Nitin Kumar, Soboczenski, Frank, Snyder, Michael, Soman, Karthik, Theriot, Corey A, Van Valen, David, Venkateswaran, Kasthuri, Warren, Liz, Worthey, Liz, Zitnik, Marinka, Costes, Sylvain V

“…Space biology research aims to understand fundamental effects of spaceflight on organisms, develop foundational knowledge to support deep space exploration,…”
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Beyond Low Earth Orbit: Biomonitoring, Artificial Intelligence, and Precision Space Health by Scott, Ryan T, Antonsen, Erik L, Sanders, Lauren M, Hastings, Jaden J. A, Park, Seung-min, Mackintosh, Graham, Reynolds, Robert J, Hoarfrost, Adrienne L, Sawyer, Aenor, Greene, Casey S, Glicksberg, Benjamin S, Theriot, Corey A, Berrios, Daniel C, Miller, Jack, Babdor, Joel, Barker, Richard, Baranzini, Sergio E, Beheshti, Afshin, Chalk, Stuart, Delgado-Aparicio, Guillermo M, Haendel, Melissa, Hamid, Arif A, Heller, Philip, Jamieson, Daniel, Jarvis, Katelyn J, Kalantari, John, Khezeli, Kia, Komarova, Svetlana V, Komorowski, Matthieu, Kothiyal, Prachi, Mahabal, Ashish, Manor, Uri, Martin, Hector Garcia, Mason, Christopher E, Matar, Mona, Mias, George I, Myers,Jr, Jerry G, Nelson, Charlotte, Oribello, Jonathan, Parsons-Wingerter, Patricia, Prabhu, R. K, Qutub, Amina Ann, Rask, Jon, Saravia-Butler, Amanda, Saria, Suchi, Singh, Nitin Kumar, Soboczenski, Frank, Snyder, Michael, Soman, Karthik, Van Valen, David, Venkateswaran, Kasthuri, Warren, Liz, Worthey, Liz, Yang, Jason H, Zitnik, Marinka, Costes, Sylvain V

“…Human space exploration beyond low Earth orbit will involve missions of significant distance and duration. To effectively mitigate myriad space health hazards,…”
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Defining metric-aware size-shape measures to validate and optimize curved high-order meshes by Aparicio-Estrems, Guillermo, Gargallo-Peiró, Abel, Roca, Xevi

“…Computer-Aided Design, Volume 168, March 2024, 103667 We define a regularized size-shape distortion (quality) measure for curved high-order elements on a…”
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