Search Results - "Aparecida Stern, Cristina"
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Posttraumatic stress disorder-type behaviors in streptozotocin-induced diabetic rats can be prevented by prolonged treatment with vitamin E
Published in Behavioural brain research (01-02-2019)“…•Streptozotocin-induced diabetes induces deficit of extinction of conditioned fear memory.•Streptozotocin-induced diabetes induces generalization of…”
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Involvement of cannabinoid receptors and neuroinflammation in early sepsis: implications for posttraumatic stress disorder
Published in International immunopharmacology (01-10-2023)“…[Display omitted] •Fear memory generalization is a model of posttraumatic stress disorder.•Rats that survived sepsis developed fear memory generalization.•The…”
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Cannabidiol effects on fear processing and implications for PTSD: Evidence from rodent and human studies
Published in International review of neurobiology (2024)“…Cannabidiol (CBD) modulates aversive memory and its extinction, with potential implications for treating anxiety- and stress-related disorders. Here, we…”
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Phosphodiesterase 4 inhibition after retrieval switches the memory fate favoring extinction instead of reconsolidation
Published in Scientific reports (21-11-2023)“…Phosphodiesterase 4 (PDE4), an enzyme expressed in the dorsal hippocampus (DH), hydrolyzes the cAMP, limiting the PKA-induced CREB phosphorylation (pCREB) and…”
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Cannabidiol modulates contextual fear memory consolidation in animals with experimentally induced type-1 diabetes mellitus
Published in Acta neuropsychiatrica (01-10-2024)“…In view of the neuroprotective characteristic of cannabidiol (CBD) and its beneficial action on aversive memory in non-diabetic animals, we aimed to…”
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Contribution of mesolimbic dopamine and kappa opioid systems to the transition from acute to chronic pain
Published in Neuropharmacology (01-11-2020)“…Decreased dopaminergic activity and increased kappa opioid activity in the mesolimbic system underlie the negative emotional states related to chronic pain…”
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Sexual dimorphism of hypothalamic serotonin release during systemic inflammation: Role of endothelin-1
Published in Journal of neuroimmunology (15-09-2024)“…The hypothalamus receives serotonergic projections from the raphe nucleus in a sex-specific manner. During systemic inflammation, hypothalamic levels of…”
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Evidence on the impairing effects of Ayahuasca on fear memory reconsolidation
Published in Psychopharmacology (01-10-2022)“…Rationale To uncover whether psychedelic drugs attenuate fear memory responses would advance the development of better psychedelic-based treatments for…”
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Effects of delta-9 tetrahydrocannabinol on fear memory labilization and reconsolidation: A putative role of GluN2B-NMDA receptor within the dorsal hippocampus
Published in Neuropharmacology (01-03-2023)“…Cannabis preparations could be an effective reconsolidation-based treatment for post-traumatic stress disorder. However, the effects of Δ9-tetrahydrocannabinol…”
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The Role of Prelimbic and Anterior Cingulate Cortices in Fear Memory Reconsolidation and Persistence Depends on the Memory Age
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-08-2020)“…Reconsolidation is a time-limited process under which reactivated memory content can be modified. Works focused on studying reconsolidation mainly restrict…”
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The Estrous Cycle Influences the Effects of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase Inhibition in the Anxiety-Like Behavior in Rats
Published in Cannabis and cannabinoid research (01-08-2024)“…Sex differences in the response to the anxiety-related effects of cannabinoid drugs have been reported, with females being more sensitive than males. Evidence…”
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Two-weeks treatment with cannabidiol improves biophysical and behavioral deficits associated with experimental type-1 diabetes
Published in Neuroscience letters (11-06-2020)“…•Diabetic rats exhibited a more pronounced depressive- and anxiogenic-like behavior.•Treatment of diabetic rats with cannabidiol induced changes in monoamine…”
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Persistence of the extinction of fear memory requires late-phase cAMP/PKA signaling in the infralimbic cortex
Published in Neurobiology of learning and memory (01-07-2020)“…[Display omitted] •Phosphodiesterase-4 inhibition 3 h after extinction improved the persistence of extinction.•Infralimbic cortex activity is associated with…”
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Female but not male rats show biphasic effects of low doses of Δ9-tetrahydrocannabinol on anxiety: can cannabidiol interfere with these effects?
Published in Neuropharmacology (15-09-2021)“…Δ9-tetrahydrocannabinol (THC) is the main phytocannabinoid present in the Cannabis sativa. It can produce dose-dependent anxiolytic or anxiogenic effects in…”
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Alterations in neurotransmitters, steroid hormones, vitellogenin, and antioxidant system induced by di-n-butyl phthalate and di-isopentyl phthalate on catfish Rhamdia quelen
Published in Environmental science and pollution research international (01-08-2024)“…Phthalates, such as di-n-butyl phthalate (DBP) and di-isopentyl phthalate (DiPeP), are pollutants with a high potential for endocrine disruption. This study…”
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Effects of ketamine on vocal impairment, gait changes, and anhedonia induced by bilateral 6-OHDA infusion into the substantia nigra pars compacta in rats: Therapeutic implications for Parkinson’s disease
Published in Behavioural brain research (16-04-2018)“…[Display omitted] Parkinson’s disease is a chronic neurodegenerative disorder characterized by cardinal motor features, such as bradykinesia, but also vocal…”
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Female but not male rats show biphasic effects of low doses of Δ 9 -tetrahydrocannabinol on anxiety: can cannabidiol interfere with these effects?
Published in Neuropharmacology (15-09-2021)“…Δ -tetrahydrocannabinol (THC) is the main phytocannabinoid present in the Cannabis sativa. It can produce dose-dependent anxiolytic or anxiogenic effects in…”
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