Search Results - "Aparecida Rocco, Silvana"

Metabolic Disturbances in the Gut-brain Axis of a Mouse Model of MPTP-induced Parkinsonism Evaluated by Nuclear Magnetic Resonance by Pedro Amorim Neto, Dionísio, Vitor Pereira de Godoy, João, Tostes, Katiane, Pelegrini Bosque, Beatriz, Vieira Rodrigues, Paulla, Aparecida Rocco, Silvana, Luis Sforça, Mauricio, de Castro Fonseca, Matheus

“…[Display omitted] •The gut-microbiota-brain axis has a role in the physiological basis of neurodegeneration.•Parkinson’s disease frequently leads to…”
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Preparative Fractionation of Brazilian Red Propolis Extract Using Step-Gradient Counter-Current Chromatography by Lopez, Begoña Gimenez-Cassina, Marcucci, Maria Cristina, Rocco, Silvana Aparecida, Sforça, Maurício Luís, Eberlin, Marcos Nogueira, Hewitson, Peter, Ignatova, Svetlana, Sawaya, Alexandra Christine Helena Frankland

“…Propolis is a resinous bee product with a very complex composition, which is dependent upon the plant sources that bees visit. Due to the promising…”
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Acetaminophen absorption and metabolism in an intestine/liver microphysiological system by Marin, Talita Miguel, de Carvalho Indolfo, Nathalia, Rocco, Silvana Aparecida, Basei, Fernanda Luisa, de Carvalho, Murilo, de Almeida Gonçalves, Kaliandra, Pagani, Eduardo

“…This study describes the characterization of pharmacokinetic (PK) properties of acetaminophen (APAP) in the Two-Organ-Chip platform (2-OC), a two-chamber…”
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Role of the Citrus sinensis RNA deadenylase CsCAF1 in citrus canker resistance by Shimo, Hugo Massayoshi, Terassi, Carolina, Lima Silva, Caio Cesar, Zanella, Jackeline de Lima, Mercaldi, Gustavo Fernando, Rocco, Silvana Aparecida, Benedetti, Celso Eduardo

“…Summary Poly(A) tail shortening is a critical step in messenger RNA (mRNA) decay and control of gene expression. The carbon catabolite repressor 4…”
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Discovery and structural characterization of chicoric acid as a SARS-CoV-2 nucleocapsid protein ligand and RNA binding disruptor by Mercaldi, Gustavo Fernando, Bezerra, Eduardo Henrique Salviano, Batista, Fernanda Aparecida Heleno, Tonoli, Celisa Caldana Costa, Soprano, Adriana Santos, Shimizu, Jacqueline Farinha, Nagai, Alice, da Silva, Jaqueline Cristina, Filho, Helder Veras Ribeiro, do Nascimento Faria, Jéssica, da Cunha, Marcos Guilherme, Zeri, Ana Carolina Mattos, Nascimento, Andrey Fabricio Ziem, Proenca-Modena, José Luiz, Bajgelman, Marcio Chaim, Rocco, Silvana Aparecida, Lopes-de-Oliveira, Paulo Sérgio, Cordeiro, Artur Torres, Bruder, Marjorie, Marques, Rafael Elias, Sforça, Mauricio Luis, Franchini, Kleber Gomes, Benedetti, Celso Eduardo, Figueira, Ana Carolina Migliorini, Trivella, Daniela Barretto Barbosa

“…The nucleocapsid (N) protein plays critical roles in coronavirus genome transcription and packaging, representing a key target for the development of novel…”
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Adenosine Kinase couples sensing of cellular potassium depletion to purine metabolism by de Oliveira, Renata Rocha, Morales-Neto, Raphael, Rocco, Silvana Aparecida, Sforça, Maurício Luis, Polo, Carla Cristina, Tonoli, Celisa Caldana Costa, Mercaldi, Gustavo Fernando, Cordeiro, Artur Torres, Murakami, Mário Tyago, Franchini, Kleber Gomes

“…Adenosine Kinase (ADK) regulates the cellular levels of adenosine (ADO) by fine-tuning its metabolic clearance. The transfer of γ-phosphate from ATP to ADO by…”
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Characterization of Brazilian floral honey produced in the states of Santa Catarina and São Paulo using quantitative nuclear magnetic resonance (qNMR) spectroscopy by Nunes, Aline, Sforça, Mauricio Luis, Rocco, Silvana Aparecida, Azevedo, Gadiel Zilto, dos Santos, Beatriz Rocha, Borges, Cristine Vanz, Lima, Giuseppina Pace Pereira, Moura, Sidnei, Maraschin, Marcelo

“…•21 metabolites were detected in honey produced in southeastern and southern Brazil.•Honey were discriminated by geographic and botanical origins using 1H NMR…”
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Integration of proteinogenic amino acids in the pathogenesis of schizophrenia by Carvalho, Michelle S., Sforca, Mauricio Luis, Rocco, Silvana Aparecida, Furtado, Danielle Zildeana Sousa, Silverio, Cristiane da Silva, Nunes, Marielle F. Queiroz, Vella Nunes, Marcel, Adelino, Marcelo P. Machado, Afonso dos Santos, Leonardo, Jackowski, Andrea, Affonseca Bressan, Rodrigo, Lacerda, Acioly Luiz Tavares, Assunção, Nilson Antônio

“…Background Schizophrenia (SCZ) is a severe mental disorder of multifactorial origin in which the role of amino acids is relatively unknown. Based on the…”
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Validation of a method for simultaneous quantification of total carotenes and tocols in vegetable oils by HPLC by Silva, Simone M., Rocco, Silvana Aparecida, Sampaio, Klicia Araújo, Taham, Thiago, da Silva, Luiza Helena Meller, Ceriani, Roberta, Meirelles, Antonio J.A.

“…► A method to quantify simultaneously carotenes and tocols was validated. ► Flow and concentration gradients improved selectivity. ► Accuracy, precision and…”
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Analysis of adenosine by RP-HPLC method and its application to the study of adenosine kinase kinetics by Marin, Rodrigo Miguel, Franchini, Kleber Gomes, Rocco, Silvana Aparecida

“…An RP-HPLC method for the analysis of adenosine (ADO) has been developed and validated. In the present study, we report an RP-HPLC-based method with…”
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3D bioprinting of liver spheroids derived from human induced pluripotent stem cells sustain liver function and viability in vitro by Goulart, Ernesto, de Caires-Junior, Luiz Carlos, Telles-Silva, Kayque Alves, Araujo, Bruno Henrique Silva, Rocco, Silvana Aparecida, Sforca, Mauricio, de Sousa, Irene Layane, Kobayashi, Gerson S, Musso, Camila Manso, Assoni, Amanda Faria, Oliveira, Danyllo, Caldini, Elia, Raia, Silvano, Lelkes, Peter I, Zatz, Mayana

“…The liver is responsible for many metabolic, endocrine and exocrine functions. Approximately 2 million deaths per year are associated with liver failure…”
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A novel approach for the production and purification of mannosylerythritol lipids (MEL) by Pseudozyma tsukubaensis using cassava wastewater as substrate by Andrade, Cristiano José de, Andrade, Lidiane Maria de, Rocco, Silvana Aparecida, Sforça, Mauricio Luis, Pastore, Gláucia Maria, Jauregi, Paula

“…•Production of mannosylerylthritol lipids using cassava wastewater.•Purification of mannosylerylthritol lipids by ultrafiltration.•Minor mannosylerylthritol…”
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High performance liquid chromatography analysis of a 4-anilinoquinazoline derivative (PD153035), a specific inhibitor of the epidermal growth factor receptor tyrosine kinase, in rat plasma by ROCCO, Silvana Aparecida, VELHO, Jesus Antonio, MARINA, Rodrigo Miguel, DE ARRUDA ROLIM, Luis FILHO, VERCESI, Anibal Eugênio, RITTNER, Roberto, GOMES FRANCHINI, Kleber

“…The quinazoline derivative, 4-N-(3'-bromo-phenyl)amino-6,7-dimethoxyquinazoline (PD153035), has recently been identified as a potential drug for the treatment…”
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Unveiling the intricacies of BPA and BPS: comprehensive insights into its toxic effects using a cutting-edge microphysiological system by Ganzerla, Melissa Dibbernn, Indolfo, Nathalia de Carvalho, Oliveira, Larissa Cleres Moreira, Doratioto, Tabata Renee, Avelino, Thayná Mendonça, de Azevedo, Rafael Junior, Tofani, Larissa Bueno, Terra, Maiara Ferreira, Elias, Giovanna Blazutti, de Sousa, Irene Layane, Alborguetti, Marcos Rodrigo, Rocco, Silvana Aparecida, Arroteia, Kelen Fabiola, Figueira, Ana Carolina Migliorini

“…Concerns over Bisphenol A (BPA) and its substitute, Bisphenol S (BPS), have led to innovative exploration due to potential adverse health effects. BPS,…”
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Structure-function relationship of a citrus salicylate methylesterase and role of salicylic acid in citrus canker resistance by Lima Silva, Caio Cesar de, Shimo, Hugo Massayoshi, de Felício, Rafael, Mercaldi, Gustavo Fernando, Rocco, Silvana Aparecida, Benedetti, Celso Eduardo

“…Salicylic acid (SA) and its methyl ester, methyl salicylate (MeSA) are well known inducers of local and systemic plant defense responses, respectively. MeSA is…”
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Acidification treatment of lignin from sugarcane bagasse results in fractions of reduced polydispersity and high free-radical scavenging capacity by Brenelli, Lívia Beatriz, Mandelli, Fernanda, Mercadante, Adriana Zerlotti, Rocha, George Jackson de Moraes, Rocco, Silvana Aparecida, Craievich, Aldo Felix, Gonçalves, Adilson Roberto, Centeno, Danilo da Cruz, de Oliveira Neto, Mario, Squina, Fabio Marcio

“…•Lignin mixture derived from sugarcane bagasse was submitted to acid fractionation.•Low-polydispersity lignin preparations with small nanometric clusters were…”
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Pyrrole-indolinone SU11652 targets the nucleoside diphosphate kinase from Leishmania parasites by Vieira, Plínio Salmazo, Souza, Tatiana de Arruda Campos Brasil, Honorato, Rodrigo Vargas, Zanphorlin, Letícia Maria, Severiano, Kelven Ulisses, Rocco, Silvana Aparecida, de Oliveira, Arthur Henrique Cavalcante, Cordeiro, Artur Torres, Oliveira, Paulo Sérgio Lopes, de Giuseppe, Priscila Oliveira, Murakami, Mário Tyago

“…Nucleoside diphosphate kinases (NDKs) are key enzymes in the purine-salvage pathway of trypanosomatids and have been associated with the maintenance of…”
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An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment by Marin, Talita Miguel, Indolfo, Nathalia de Carvalho, Rocco, Silvana Aparecida, de Carvalho, Murilo, Dias, Marilia Meira, Vasconcelos Bento, Graziele Izalina, Bortot, Leandro Oliveira, Schuck, Desirée Cigaran, Lorencini, Márcio, Pagani, Eduardo

“…The recently introduced microphysiological systems (MPS) cultivating human organoids are expected to perform better than animals in the preclinical tests phase…”
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