Search Results - "Aparajit B Dey"
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Sirtuin1: a promising serum protein marker for early detection of Alzheimer's disease
Published in PloS one (16-04-2013)“…Sirtuin (SIRT) pathway has a crucial role in Alzheimer's disease (AD). The present study evaluated the alterations in serum sirtuin1 (SIRT1) concentration in…”
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Estimation of Tau and Phosphorylated Tau181 in Serum of Alzheimer's Disease and Mild Cognitive Impairment Patients
Published in PloS one (01-07-2016)“…The elevated level of cerebrospinal fluid (CSF) Tau and phosphorylated Tau181 (p-Tau181) proteins are well established hallmarks of Alzheimer's disease (AD)…”
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The association between BMI and cognition in India: data from the Longitudinal Aging Study in India (LASI)
Published in BMC public health (05-10-2024)“…High body-mass index (BMI) is an established risk factor for late-life cognitive impairment and dementia, but most evidence comes from high-income contexts…”
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Polygenic Risk Scores for Alzheimer’s Disease and General Cognitive Function Are Associated With Measures of Cognition in Older South Asians
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (11-05-2023)“…Abstract Genome-wide association studies (GWAS) conducted in European ancestry (EA) have identified hundreds of single-nucleotide polymorphisms (SNPs)…”
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Profiles of Older Patients in the Emergency Department: Findings From the interRAI Multinational Emergency Department Study
Published in Annals of emergency medicine (01-11-2013)“…Study objective We examine functional profiles and presence of geriatric syndromes among older patients attending 13 emergency departments (EDs) in 7 nations…”
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Relative Alterations in Blood-Based Levels of Sestrin in Alzheimer's Disease and Mild Cognitive Impairment Patients
Published in Journal of Alzheimer's disease (04-10-2016)“…Sestrins (sesn) are highly conserved proteins that play an important neuroprotective role, in part as a consequence of their antioxidative capacity, which…”
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Exploration of Novel Anti-Oxidant Protein Sestrin in Frailty Syndrome in Elderly
Published in Aging and disease (01-04-2018)“…Frailty in elderly is very much familiar with a decline in the musculoskeletal system. Muscle degeneration in the lower organism was observed due to loss of…”
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Trajectories and correlates of poor mental health in India over the course of the COVID-19 pandemic: a nationwide survey
Published in BMJ global health (29-01-2024)“…IntroductionThe COVID-19 pandemic had large impacts on mental health; however, most existing evidence is focused on the initial lockdown period and high-income…”
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Effect of deep tissue laser therapy treatment on peripheral neuropathic pain in older adults with type 2 diabetes: a pilot randomized clinical trial
Published in BMC geriatrics (12-08-2019)“…This study assessed the safety and efficacy of deep tissue laser therapy on the management of pain, functionality, systemic inflammation, and overall quality…”
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Introduction to LASI‐DAD: The Longitudinal Aging Study in India‐Diagnostic Assessment of Dementia
Published in Journal of the American Geriatrics Society (JAGS) (01-08-2020)Get full text
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Inhibiting the Programmed Death 1 Pathway Rescues Mycobacterium tuberculosis-Specific Interferon γ-Producing T Cells From Apoptosis in Patients With Pulmonary Tuberculosis
Published in The Journal of infectious diseases (15-08-2013)“…Background. Overexpression of programmed death 1 (PD-1) receptor is thought to inhibit the effector T-cell response in human tuberculosis. However, the precise…”
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Development of integrated care tool - BRIEF for screening the unmet psychosociomedical needs of older Indians
Published in Indian journal of public health (01-01-2019)“…Background: With demographic shifts, there is an unprecedented increase in noncommunicable diseases, multimorbidity, and geriatric syndromes among older…”
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Online Clinical Consensus Diagnosis of Dementia: Development and Validation
Published in Journal of the American Geriatrics Society (JAGS) (01-08-2020)“…OBJECTIVES To introduce cost‐effective expert clinical diagnoses of dementia into population‐based research using an online platform and to demonstrate their…”
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Design and Methodology of the Longitudinal Aging Study in India‐Diagnostic Assessment of Dementia (LASI‐DAD)
Published in Journal of the American Geriatrics Society (JAGS) (01-08-2020)“…BACKGROUND/OBJECTIVES To provide high‐quality data on older adults in India that will enable an in‐depth study of late‐life cognition and dementia in India and…”
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Identification of serum sirtuins as novel noninvasive protein markers for frailty
Published in Aging cell (01-12-2014)“…Summary Frailty has emerged as a major health issue among older patients. A consensus on definition and diagnosis is yet to be achieved. Various biochemical…”
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Effect of apolipoprotein E ε4 and its modification by sociodemographic characteristics on cognitive measures in South Asians from LASI‐DAD
Published in Alzheimer's & dementia (01-07-2024)“…BACKGROUND We investigated the effects of apolipoprotein E (APOE) ε4 and its interactions with sociodemographic characteristics on cognitive measures in South…”
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Molecular characterization of Clostridioides difficile by multi-locus sequence typing (MLST): A study from tertiary care center in India
Published in Anaerobe (01-06-2022)“…Clostridioides difficile is an important pathogen responsible for antibiotic-associated diarrhoea (AAD). This study was aimed to perform multi-locus sequence…”
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Drug-resistant Salmonella enterica serotype paratyphi A in India
Published in Emerging infectious diseases (01-07-2000)“…The incidence of enteric fever caused by Salmonella enterica serotype Paratyphi A has been increasing in India since 1996. In 1998, the incidence of enteric…”
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Association Between Episodic Memory and Genetic Risk Factors for Alzheimer's Disease in South Asians from the Longitudinal Aging Study in India–Diagnostic Assessment of Dementia (LASI‐DAD)
Published in Journal of the American Geriatrics Society (JAGS) (01-08-2020)“…BACKGROUND/OBJECTIVES Genetic factors play an important role in Alzheimer's disease (AD) and cognitive aging. However, it is unclear whether risk loci…”
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5-LOX in Alzheimer’s Disease: Potential Serum Marker and In Vitro Evidences for Rescue of Neurotoxicity by Its Inhibitor YWCS
Published in Molecular neurobiology (01-04-2018)“…The inflammatory process plays a key role in neurodegenerative disorder. The inflammatory molecule, 5-lipooxygenase (5-LOX), protein is involved in the…”
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