Seroprevalence, trends, and risk factors of hepatitis B and C among family replacement blood donors; a 7-year retrospective study at Sunyani Municipal Hospital, Ghana

Seroprevalence, trends, and risk factors of hepatitis B and C among family replacement blood donors; a 7-year retrospective study at Sunyani Municipal Hospital, Ghana

Hepatitis B and C cause chronic infections which develop into liver-related sequelae, like cirrhosis and liver carcinoma. This study determined the seroprevalence, trends, and risk factors of HBV and HCV among family replacement donors. A retrospective review of primary data on blood donors screened...

Full description

Saved in:
Bibliographic Details
Published in:Journal of immunoassay & immunochemistry Vol. 44; no. 2; pp. 162 - 175
Main Authors: Osei-Boakye, Felix, Nkansah, Charles, Appiah, Samuel Kwasi, Derigubah, Charles Angnataa, Mensah, Kofi, Apandago, Abraham Azumah, Boateng, Vida Animah, Norsi, Obed Gadufia, Kogh-Nuu, Dominic
Format: Journal Article
Language:English
Published: England Taylor & Francis 04-03-2023
Marcel Dekker, Inc
Subjects:
Blood & organ donations
Blood Donors
Blood groups
Cirrhosis
Complications
Female
Ghana
Hepatitis
Hepatitis B
Hepatitis C
HIV Infections
Hospitals, Municipal
Humans
Infections
Liver
Male
Males
Rainy season
replacement donor
Retrospective Studies
risk factor
Risk Factors
Seasons
Seroepidemiologic Studies
Serology
seroprevalence
Syphilis
trend
Trends
Ghana
seroprevalence
Hepatitis
replacement donor
trend
risk factor
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Hepatitis B and C cause chronic infections which develop into liver-related sequelae, like cirrhosis and liver carcinoma. This study determined the seroprevalence, trends, and risk factors of HBV and HCV among family replacement donors. A retrospective review of primary data on blood donors screened between January 2015 and December 2021 was conducted at Sunyani Municipal Hospital. The data were assessed for seroprevalence, trends, and odds ratios using SPSS. Of 6847 donors, the majority were males (88.1% [6033]), ≤24 years (27.4% [1874]), O blood type (69.8% [4776]), and Rh-positive (89.9% [6154]). The seroprevalences of HBV and HCV were 3.2% and 1.9%, respectively, with more males infected with HBV and HCV (3.4% vs 2.0%). Males were 2.842 times (p = .001) and 2.399 times (p = .025) more susceptible than females to HBV and HCV, respectively. In the rainy season, donors were 1.489 times (p = .041) more susceptible to HCV. HBV and HCV seroprevalence declined over the period (slope: −0.5464, p ≤ .001 vs slope: −0.6179, p ≤ .001). Male gender and rainy season were significant determinants of both infections. The seroprevalence of HBV was higher than HCV despite the significant decline in both infections. We, recommend health authorities intensify health education among males and during the rainy season.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1532-1819
1532-4230
DOI:10.1080/15321819.2023.2168555