Search Results - "Aoki, Naohito"

Identification and Characterization of Microvesicles Secreted by 3T3-L1 Adipocytes: Redox- and Hormone-Dependent Induction of Milk Fat Globule-Epidermal Growth Factor 8-Associated Microvesicles by Aoki, Naohito, Jin-no, Shinji, Nakagawa, Yoshimi, Asai, Noriyuki, Arakawa, Erina, Tamura, Noriko, Tamura, Tomohiro, Matsuda, Tsukasa

“…Adipocytes are now recognized as endocrine cells secreting adipocytokines, regulating multiple metabolic pathways. In this study, we addressed secretion of…”
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A Cytosolic Protein-tyrosine Phosphatase PTP1B Specifically Dephosphorylates and Deactivates Prolactin-activated STAT5a and STAT5b by Aoki, Naohito, Matsuda, Tsukasa

“…Prolactin (PRL) plays a central and crucial role in the regulation of milk protein gene expression in mammary epithelial cells. PRL binding to its cognate…”
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A Nuclear Protein Tyrosine Phosphatase TC-PTP Is a Potential Negative Regulator of the PRL-Mediated Signaling Pathway: Dephosphorylation and Deactivation of Signal Transducer and Activator of Transcription 5a and 5b by TC-PTP in Nucleus by Aoki, Naohito, Matsuda, Tsukasa

“…In the present study we examined involvement of nuclear protein tyrosine phosphatase TC-PTP in PRL-mediated signaling. TC-PTP could dephosphorylate signal…”
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RETRACTED ARTICLE: Regulation and Functional Relevance of Milk Fat Globules and Their Components in the Mammary Gland by AOKI, Naohito

“…Mammary gland and epithelial cells are unique to mammals and are under the control of lactogenic hormones such as prolactin. Recent findings indicated that…”
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The nuclear isoform of protein-tyrosine phosphatase TC-PTP regulates interleukin-6-mediated signaling pathway through STAT3 dephosphorylation by Yamamoto, Tetsuya, Sekine, Yuichi, Kashima, Keiichi, Kubota, Atsuko, Sato, Noriko, Aoki, Naohito, Matsuda, Tadashi

“…In the previous study, we demonstrated that the nuclear isoform of T-cell protein-tyrosine phosphatase (TC-PTP) dephosphorylated and deactivated signal…”
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Absorption, migration and kinetics in peripheral blood of orally administered ovalbumin in a mouse model by Matsubara, T.(Nagoya Univ. (Japan)), Aoki, N, Honjoh, T, Mizumachi, K, Kurisaki, J, Okajima, T, Nadano, D, Matsuda, T

“…Intestinal absorption of food proteins is well known, whereas its physiological significance remains to be investigated. Various amounts (1, 10 and 50 mg) of…”
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Transplantation of a Mammary Stromal Cell Line into a Mammary Fat Pad: Development of the Site-Specific in Vivo Analysis System for Mammary Stromal Cells by NAKATANI, Hajime, AOKI, Naohito, NADANO, Daita, MATSUDA, Tsukasa

“…The interaction between mammary epithelial and stromal tissue is considered to be important in breast tissue development. In this study, we developed a…”
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A food‐derived synergist of NGF signaling: identification of protein tyrosine phosphatase 1B as a key regulator of NGF receptor‐initiated signal transduction by Shibata, Takahiro, Nakahara, Hiroko, Kita, Narumi, Matsubara, Yui, Han, Chunguang, Morimitsu, Yasujiro, Iwamoto, Noriko, Kumagai, Yoshito, Nishida, Motohiro, Kurose, Hitoshi, Aoki, Naohito, Ojika, Makoto, Uchida, Koji

“…Neurotrophins, such as the nerve growth factor (NGF), play an essential role in the growth, development, survival and functional maintenance of neurons in the…”
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A newly identified zona pellucida glycoprotein, ZPD, and dimeric ZP1 of chicken egg envelope are involved in sperm activation on sperm-egg interaction by Okumura, Hiroki, Kohno, Yoshinori, Iwata, Yuki, Mori, Hitoshi, Aoki, Naohito, Sato, Chihiro, Kitajima, Ken, Nadano, Daita, Matsuda, Tsukasa

“…Fertilization begins with interaction between the sperm and the egg. The surface of the vertebrate oocyte is covered with the egg envelope, which is composed…”
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Binding of Norovirus virus-like particles (VLPs) to human intestinal Caco-2 cells and the suppressive effect of pasteurized bovine colostrum on this VLP binding by Murakami, K., Nagoya Univ. (Japan), Suzuki, S, Aoki, N, Okajima, T, Nadano, D, Uchida, K, Yamashita, K, Oka, T, Katayama, K, Takeda, N, Matsuda, T

“…Noroviruses (NoVs), which cannot be grown in cell culture, are a major infectious agent of gastroenteritis. An in vitro assay system was established for the…”
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Development and evaluation of transgenic rice seeds accumulating a type II-collagen tolerogenic peptide by Hashizume, Fujio, Hino, Shingo, Kakehashi, Misako, Okajima, Tetsuya, Nadano, Daita, Aoki, Naohito, Matsuda, Tsukasa

“…Type II collagen (CII) in joint cartilage is known to be a major auto-antigen in human rheumatoid arthritis. Several animal model- and clinical-studies on…”
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Establishment of a Mammary Stromal Fibroblastic Cell Line for In Vitro Studies in Mice of Mammary Adipocyte Differentiation1 by Nakatani, Hajime, Aoki, Naohito, Okajima, Tetsuya, Nadano, Daita, Flint, David, Matsuda, Tsukasa

“…Mammary stromal adipose tissue remodeling is important for appropriate mammary gland development during pregnancy, lactation, and involution. However, the…”
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Critical Role of Calcium- dependent Epidermal Growth Factor Receptor Transactivation in PC12 Cell Membrane Depolarization and Bradykinin Signaling by Zwick, Esther, Daub, Henrik, Aoki, Naohito, Yamaguchi-Aoki, Yumiko, Tinhofer, Inge, Maly, Karl, Ullrich, Axel

“…PC12 cells respond to a variety of external stimuli such as growth factors, neurotransmitters, and membrane depolarization by activating the…”
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Receptor-type protein tyrosine phosphatase epsilon (PTPepsilonM) is a negative regulator of insulin signaling in primary hepatocytes and liver by Nakagawa, Yoshimi, Aoki, Naohito, Aoyama, Koji, Shimizu, Hidehisa, Shimano, Hitoshi, Yamada, Nobuhiro, Miyazaki, Hitoshi

“…Impaired insulin receptor (IR) signaling leads to insulin resistance and type 2 diabetes mellitus. Several inhibitors of the IR tyrosine kinase activity have…”
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Molecular Cloning and Characterization of a Novel Dual Specificity Phosphatase, LMW-DSP2, That Lacks the Cdc25 Homology Domain by Aoyama, Koji, Nagata, Miyuki, Oshima, Kenji, Matsuda, Tsukasa, Aoki, Naohito

“…A novel dual specificity phosphatase (DSP) designated LMW-DSP2 was cloned with a combination of reverse transcription-polymerase chain reaction and cDNA…”
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Isolation of bovine milk-derived microvesicles carrying mRNAs and microRNAs by Hata, Taketoshi, Murakami, Kosuke, Nakatani, Hajime, Yamamoto, Yasunari, Matsuda, Tsukasa, Aoki, Naohito

“…By a series of centrifugation and ultracentrifugation, we could isolate microvesicles with approximately 100 nm in diameter from bovine milk. We also found…”
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Secreted membrane vesicles: components and biological functions by Aoki, Naohito, Matsuda, Tsukasa

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Mutual Regulation of Protein-tyrosine Phosphatase 20 and Protein-tyrosine Kinase Tec Activities by Tyrosine Phosphorylation and Dephosphorylation by Aoki, Naohito, Ueno, Shuichi, Mano, Hiroyuki, Yamasaki, Sho, Shiota, Masayuki, Miyazaki, Hitoshi, Yamaguchi-Aoki, Yumiko, Matsuda, Tsukasa, Ullrich, Axel

“…PTP20, also known as HSCF/protein-tyrosine phosphatase K1/fetal liver phosphatase 1/brain-derived phosphatase 1, is a cytosolic protein-tyrosine phosphatase…”
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Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation by Ogawa, Rumiko, Tanaka, Chie, Sato, Masahiro, Nagasaki, Haruka, Sugimura, Kazuto, Okumura, Katsuzumi, Nakagawa, Yoshimi, Aoki, Naohito

“…► Adipocyte-derived microvesicles (ADMs) contained mRNAs and microRNAs. ► The level of ADM-derived RNAs was mostly correlated with that of donor adipocytes. ►…”
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Morphological and Biochemical Changes of Isolated Chicken Egg-Envelope During Sperm Penetration: Degradation of the 97-Kilodalton Glycoprotein Is Involved in Sperm-Driven Hole Formation on the Egg-Envelope by TAKEUCHI, Yukinari, CHO, Ritsuko, IWATA, Yuki, NISHIMURA, Keiji, KATO, Takeo, AOKI, Naohito, KITAJIMA, Ken, MATSUDA, Tsukasa

“…The chicken egg-envelope is made of two major glycoprotein components, which are designated as gp97 and gp42 (after their molecular masses). To elucidate how…”
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