Search Results - "Ao, Tomoka"
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The Effects of Vitamin D on Immune System and Inflammatory Diseases
Published in Biomolecules (Basel, Switzerland) (03-11-2021)“…Immune cells, including dendritic cells, macrophages, and T and B cells, express the vitamin D receptor and 1α-hydroxylase. In vitro studies have shown that…”
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Osteoblast-derived vesicles induce a switch from bone-formation to bone-resorption in vivo
Published in Nature communications (24-02-2022)“…Bone metabolism is regulated by the cooperative activity between bone-forming osteoblasts and bone-resorbing osteoclasts. However, the mechanisms mediating the…”
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PGE2 induced in and released by dying cells functions as an inhibitory DAMP
Published in Proceedings of the National Academy of Sciences - PNAS (05-04-2016)“…Cellular components released into the external milieu as a result of cell death and sensed by the body are generally termed damage-associated molecular…”
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Local sympathetic neurons promote neutrophil egress from the bone marrow at the onset of acute inflammation
Published in International immunology (20-10-2020)“…Abstract The sympathetic nervous system plays critical roles in the differentiation, maturation and recruitment of immune cells under homeostatic conditions,…”
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Thrombomodulin induces anti-inflammatory effects by inhibiting the rolling adhesion of leukocytes in vivo
Published in Journal of pharmacological sciences (01-05-2020)“…Thrombomodulin (TM) is an integral membrane protein expressed on the surface of vascular endothelial cells that suppresses blood coagulation. Recent studies…”
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Generation of mice deficient in RNA-binding motif protein 3 (RBM3) and characterization of its role in innate immune responses and cell growth
Published in Biochemical and biophysical research communications (22-07-2011)“…► We identified RNA-binding motif protein 3 (RBM3) as CpG-B DNA-binding protein. ► RBM3 translocates from the nucleus to the cytoplasm and co-localized with…”
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Group 2 innate lymphoid cells support hematopoietic recovery under stress conditions
Published in The Journal of experimental medicine (03-05-2021)“…The cell-cycle status of hematopoietic stem and progenitor cells (HSPCs) becomes activated following chemotherapy-induced stress, promoting bone marrow (BM)…”
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Two Cases of Gouty Sacroiliitis Evaluated by Dual-energy Computed Tomography
Published in Journal of rheumatology (01-06-2016)Get full text
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Anti-Siglec-15 antibody suppresses bone resorption by inhibiting osteoclast multinucleation without attenuating bone formation
Published in Bone (New York, N.Y.) (01-11-2021)“…Anti-resorptive drugs are widely used for the treatment of osteoporosis, but excessive inhibition of osteoclastogenesis can suppress bone turnover and cause…”
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