Search Results - "Anzinger, Joshua J"
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Seroprevalence of Chikungunya Virus, Jamaica, and New Tools for Surveillance (Response)
Published in Emerging infectious diseases (01-08-2022)“…In their commentary the authors note that the low number of chikungunya cases captured through passive surveillance underrepresents the true burden of disease…”
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Dengue Virus Serotype 3 Origins and Genetic Dynamics, Jamaica
Published in Emerging infectious diseases (01-10-2024)“…We identified 3 clades of dengue virus serotype 3 belonging to genotype III isolated during 2019-2020 in Jamaica by using whole-genome sequencing and…”
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Emerging Role and Characterization of Immunometabolism: Relevance to HIV Pathogenesis, Serious Non-AIDS Events, and a Cure
Published in The Journal of immunology (1950) (01-06-2016)“…Immune cells cycle between a resting and an activated state. Their metabolism is tightly linked to their activation status and, consequently, functions. Ag…”
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Antenatal Seroprevalence of Zika and Chikungunya Viruses, Kingston Metropolitan Area, Jamaica, 2017-2019
Published in Emerging infectious diseases (01-02-2022)“…To determine the extent of exposure to Zika virus (ZIKV) and chikungunya virus (CHIKV) in Jamaica, we collected serum from 584 pregnant women during 2017-2019…”
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Fluid-phase pinocytosis of native low density lipoprotein promotes murine M-CSF differentiated macrophage foam cell formation
Published in PloS one (11-03-2013)“…During atherosclerosis, low-density lipoprotein (LDL)-derived cholesterol accumulates in macrophages to form foam cells. Macrophage uptake of LDL promotes foam…”
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Dysregulated TGF-β Production Underlies the Age-Related Vulnerability to Chikungunya Virus
Published in PLoS pathogens (01-10-2016)“…Chikungunya virus (CHIKV) is a re-emerging global pathogen with pandemic potential, which causes fever, rash and debilitating arthralgia. Older adults over 65…”
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Monocytes as Regulators of Inflammation and HIV-Related Comorbidities during cART
Published in Journal of immunology research (01-01-2014)“…Combined antiretroviral therapy (cART) extends the lifespan and the quality of life for HIV-infected persons but does not completely eliminate chronic immune…”
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Urgent need to prevent mother-to-child transmission of HTLV-1 in Jamaica
Published in Lancet Regional Health - Americas (Online) (01-07-2024)Get full text
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The Others: A Systematic Review of the Lesser-Known Arboviruses of the Insular Caribbean
Published in Viruses (25-03-2023)“…The Caribbean enjoys a long-standing eminence as a popular tourist destination; however, over the years it has also amassed the sobriquet "arbovirus hotspot"…”
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ABCG1-mediated generation of extracellular cholesterol microdomains
Published in Journal of lipid research (01-01-2014)“…Previous studies have demonstrated that the ATP-binding cassette transporters (ABC)A1 and ABCG1 function in many aspects of cholesterol efflux from…”
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Assessment of commercial SARS-CoV-2 antibody assays, Jamaica
Published in International journal of infectious diseases (01-04-2021)“…•SARS-CoV-2 antibody assays have low sensitivity for asymptomatic and mild disease•Moderate to critical COVID-19 is associated with a positive antibody…”
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Native Low-Density Lipoprotein Uptake by Macrophage Colony-Stimulating Factor-Differentiated Human Macrophages Is Mediated by Macropinocytosis and Micropinocytosis
Published in Arteriosclerosis, thrombosis, and vascular biology (01-10-2010)“…OBJECTIVE—To examine the pinocytotic pathways mediating native low-density lipoprotein (LDL) uptake by human macrophage colony-stimulating…”
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Prevalence of SARS-CoV-2 antibodies after the Omicron surge, Kingston, Jamaica, 2022
Published in Journal of clinical virology plus (01-11-2022)“…A cross-sectional SARS-CoV-2 serosurvey was conducted after the Omicron surge in Jamaica using 1,540 samples collected during March – May 2022 from persons…”
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Murine bone marrow-derived macrophages differentiated with GM-CSF become foam cells by PI3Kγ-dependent fluid-phase pinocytosis of native LDL[S]
Published in Journal of lipid research (01-01-2012)“…Accumulation of cholesterol by macrophage uptake of LDL is a key event in the formation of atherosclerotic plaques. Previous research has shown that…”
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Extracellular cholesterol-rich microdomains generated by human macrophages and their potential function in reverse cholesterol transport
Published in Journal of lipid research (01-08-2010)“…Previous studies have shown that cholesterol in atherosclerotic plaques is present in both intracellular and extracellular forms. In the current study, we…”
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Zika virus evolution and spread in the Americas
Published in Nature (London) (15-06-2017)“…One hundred and ten Zika virus genomes from ten countries and territories involved in the Zika virus epidemic reveal rapid expansion of the epidemic within…”
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Chikungunya Virus Infection and Acute Elevation of Serum Prostate-Specific Antigen
Published in Case reports in urology (01-01-2015)“…A man with prostate cancer on a regime of active surveillance had a laboratory-confirmed acute Chikungunya virus infection. The patient experienced a sudden…”
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Tiger in the sun: A report of Aedes albopictus in Jamaica
Published in Acta tropica (01-11-2019)“…This report describes the presence of Aedes albopictus (Skuse) in Jamaica. The adults were found while conducting an ongoing survey of mosquitoes on the…”
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Glucose transporter 1-expressing proinflammatory monocytes are elevated in combination antiretroviral therapy-treated and untreated HIV+ subjects
Published in The Journal of immunology (1950) (01-12-2014)“…Monocyte activation during HIV-1 infection is associated with increased plasma levels of inflammatory markers and increased risk for premature development of…”
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Evaluation of transduction efficiency in macrophage colony-stimulating factor differentiated human macrophages using HIV-1 based lentiviral vectors
Published in BMC biotechnology (31-01-2011)“…Monocyte-derived macrophages contribute to atherosclerotic plaque formation. Therefore, manipulating macrophage function could have significant therapeutic…”
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