Search Results - "Anwyl, R"

Metabotropic glutamate receptor-dependent long-term potentiation by Anwyl, R.

“…The induction of the most common form of LTP is well known to involve activation of N-methyl-d-aspartate receptors. However, considerable evidence has also…”
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Enhancement of long-term depression by soluble amyloid β protein in rat hippocampus is mediated by metabotropic glutamate receptor and involves activation of p38MAPK, STEP and caspase-3 by Chen, X, Lin, R, Chang, L, Xu, S, Wei, X, Zhang, J, Wang, C, Anwyl, R, Wang, Q

“…Highlights • Aβ-enhanced hippocampal LTD depends on mGluR1/5 but not NMDAR. • Aβ-enhanced hippocampal LTD requires the activation of p38MAPK, PTPs and…”
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Synaptic memory mechanisms: Alzheimer's disease amyloid beta-peptide-induced dysfunction by Rowan, M J, Klyubin, I, Wang, Q, Hu, N W, Anwyl, R

“…There is growing evidence that mild cognitive impairment in early AD (Alzheimer's disease) may be due to synaptic dysfunction caused by the accumulation of…”
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Synaptic plasticity disruption by amyloid beta protein: modulation by potential Alzheimer's disease modifying therapies by Rowan, M J, Klyubin, I, Wang, Q, Anwyl, R

“…AD (Alzheimer's disease) is characterized by a progressive and devastating mental decline that is usually presaged by impairment of a form of memory dependent…”
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Developmental dependence, the role of the kinases p38 MAPK and PKC, and the involvement of tumor necrosis factor-R1 in the induction of mGlu-5 LTD in the dentate gyrus by Wang, Q, Chang, L, Rowan, M.J, Anwyl, R

“…Abstract The mechanisms of mGluR-LTD were studied in the dentate gyrus in vitro . The most effective protocol for inducing mGluR-LTD in 6–8 week animals was…”
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Muscarinic acetylcholine receptor-dependent induction of persistent synaptic enhancement in rat hippocampus in vivo by Li, S, Cullen, W.K, Anwyl, R, Rowan, M.J

“…Abstract Presynaptic terminal autoinhibitory muscarinic acetylcholine (ACh) receptors are predominantly of the M2/M4 subtypes and antagonists at these…”
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Synaptically stimulated induction of group i metabotropic glutamate receptor-dependent long-term depression and depotentiation is inhibited by prior activation of metabotropic glutamate receptors and PROTEIN KINASE C by Wu, J, Rowan, M.J, Anwyl, R

“…We have investigated metaplasticity of the group I metabotropic glutamate receptor (mGluR)-dependent long-term depression (LTD) and depotentiation (DP) induced…”
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A role for protein kinase A and protein kinase Mζ in muscarinic acetylcholine receptor–initiated persistent synaptic enhancement in rat hippocampus in vivo by Hayes, J, Li, S, Anwyl, R, Rowan, M.J

“…Abstract Antagonists at presynaptic muscarinic autoreceptors increase endogenous acetylcholine (ACh) release and enhance cognition but little is known…”
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Mechanisms underlying the inhibition of long-term potentiation by preconditioning stimulation in the hippocampus in vitro by Gisabella, B, Rowan, M.J, Anwyl, R

“…We have investigated the mechanisms underlying a form of metaplasticity, namely the inhibition by preconditioning stimulation of high frequency stimulation…”
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Metabotropic glutamate receptor-induced homosynaptic long-term depression and depotentiation in the dentate gyrus of the rat hippocampus in vitro by O'Mara, S.M., Rowan, M.J., Anwyl, R.

“…We have investigated the role of metabotropic glutamate receptors (mGluR) in the induction of homosynaptic long-term depression (LTD) and depotentiation (DP)…”
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Modulation of vertebrate neuronal calcium channels by transmitters by Anwyl, R

“…A large number of neurotransmitters have now been shown to reduce the amplitude and slow the activation kinetics of whole cell HVA ICa in a great diversity of…”
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Role of protein kinase C in the induction of homosynaptic long-term depression by brief low frequency stimulation in the dentate gyrus of the rat hippocampus in vitro by Wang, Y., Wu, J., Rowan, M. J., Anwyl, R.

“…Enhancement of the induction of long-term depression (LTD) of excitatory postsynaptic currents (EPSCs) by a priming stimulus was investigated in the medial…”
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Ryanodine produces a low frequency stimulation-induced NMDA receptor-independent long-term potentiation in the rat dentate gyrus in vitro by Wang, Y, Wu, J, Rowan, M J, Anwyl, R

“…1. The induction of long-term potentiation (LTP) was investigated in the rat dentate gyrus in the presence of ryanodine, an agent which is known to selectively…”
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Neurophysiological actions of 5-hydroxytryptamine in the vertebrate nervous system by Anwyl, R

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mGluR II agonist inhibition of LTP induction, and mGluR II antagonist inhibition of LTD induction, in the dentate gyrus in vitro by Huang, LingQian, Rowan, Michael J, Anwyl, R

“…THE effects of the metabotropic glutamate receptor (mGluR) group II agonist (2S,1′R,2′R,3′R)-2-(2′,3′-dicarboxycyclopropyl)glycine (DCG-IV) and the antagonist…”
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Metabotropic glutamate receptor dependent EPSP and EPSP-spike potentiation in area CA1 of the submerged rat hippocampal slice by Breakwell, N A, Rowan, M J, Anwyl, R

“…1. We reexamined the important areas of conflict in (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid [(1S,3R)-ACPD]-induced potentiation of the field…”
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Trans-ACPD enhances long-term potentiation in the hippocampus by McGuinness, N, Anwyl, R, Rowan, M

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Evidence for involvement of the neuronal isoform of nitric oxide synthase during induction of long-term potentiation and long-term depression in the rat dentate gyrus in vitro by WU, J, WANG, Y, ROWAN, M. J, ANWYL, R

“…The possible role of nitric oxide in the induction of long-term potentiation and long-term depression of field excitatory postsynaptic potentials in the…”
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Mini-review: Metabotropic glutamate receptor-dependent long-term potentiation by Anwyl, R

“…The induction of the most common form of LTP is well known to involve activation of N-methyl-d-aspartate receptors. However, considerable evidence has also…”
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Role of protein kinases A and C in the induction of mglur-dependent long-term depression in the medial perforant path of the rat dentate gyrus in vitro by HUANG, L.-Q, ROWAN, M. J, ANWYL, R

“…The involvement of protein kinases A and C in the induction of low frequency stimulation-induced long-term depression (LTD) in the medial perforant path of the…”
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