Retinopathy of Prematurity in Bangladeshi Neonates

Background: Retinopathy of prematurity (ROP) is a potentially blinding eye disorder that primarily affects premature infants. Increased survival of extremely low birth weight infants following advances in antenatal and neonatal care has resulted in a population of infants at high risk of developing...

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Bibliographic Details
Published in:	Journal of tropical pediatrics (1980) Vol. 54; no. 5; pp. 333 - 339
Main Authors:	Ahmed, A. S. M. Nawshad Uddin, Muslima, Humaira, Anwar, Kazi Shabbir, Khan, Naila Z., Chowdhury, M. A. K. Azad, Saha, Samir K., Darmstadt, Gary L.
Format:	Journal Article
Language:	English
Published:	Oxford Oxford University Press 01-10-2008 Oxford Publishing Limited (England)
Subjects:	Bangladesh - epidemiology Biological and medical sciences Blindness - prevention & control Diseases of mother, fetus and pregnancy Emollients - administration & dosage Female Follow-Up Studies General aspects Gestational Age Gynecology. Andrology. Obstetrics Humans Infant, Extremely Low Birth Weight Infant, Newborn Infant, Very Low Birth Weight Male Medical sciences neonatal Neonatal Screening Ophthalmic Solutions Ophthalmology Pregnancy. Fetus. Placenta prematurity Retinopathies retinopathy of prematurity Retinopathy of Prematurity - diagnosis Retinopathy of Prematurity - drug therapy Retinopathy of Prematurity - epidemiology Retinopathy of Prematurity - prevention & control Retrospective Studies Risk Factors Treatment Outcome Bangladesh neonatal retinopathy of prematurity prematurity Human Pediatrics Eye disease Newborn Retinopathy Prematurity Tropical medicine
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Summary:	Background: Retinopathy of prematurity (ROP) is a potentially blinding eye disorder that primarily affects premature infants. Increased survival of extremely low birth weight infants following advances in antenatal and neonatal care has resulted in a population of infants at high risk of developing ROP. Long term morbidity of ROP has a spectrum ranging from myopia to blindness. Screening programs and early intervention can provide enormous economic and social benefits. Materials and Methods: Preterm infants of gestational age <33 weeks admitted to the Special Care Nursery of Dhaka Shishu Hospital for a trial of topical emollient therapy during December 1998–July 2003 were followed-up after hospital discharge, including detailed ophthalmologic examination. Detailed history regarding risks during pregnancy, delivery and hospital stay was documented. ROP cases were managed according to the stage of the disease at diagnosis. Results: Five out of the 114 (4.4%) children seen in follow-up were diagnosed with ROP. Low gestational age, low birth weight, administration of oxygen, apneic spells, sepsis and blood transfusions were common factors among cases who developed ROP. Conclusion: As survival of preterm infants in low resource settings increases, ROP will become increasingly important as a potential cause of blindness, emphasizing the critical need for ophthalmologic examination in premature infants, with immediate initiation of treatment when ROP is diagnosed.
Bibliography:	ark:/67375/HXZ-CW241V8B-J istex:619270C76143960080C853A278D574B1F11884A1 ArticleID:fmn035 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1
ISSN:	0142-6338 1465-3664
DOI:	10.1093/tropej/fmn035