Search Results - "Anvar, Nazanin Esmaeili"

Discovery of putative tumor suppressors from CRISPR screens reveals rewired lipid metabolism in acute myeloid leukemia cells by Lenoir, W. Frank, Morgado, Micaela, DeWeirdt, Peter C., McLaughlin, Megan, Griffith, Audrey L., Sangree, Annabel K., Feeley, Marissa N., Esmaeili Anvar, Nazanin, Kim, Eiru, Bertolet, Lori L., Colic, Medina, Dede, Merve, Doench, John G., Hart, Traver

“…CRISPR knockout fitness screens in cancer cell lines reveal many genes whose loss of function causes cell death or loss of fitness or, more rarely, the…”
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Efficient gene knockout and genetic interaction screening using the in4mer CRISPR/Cas12a multiplex knockout platform by Esmaeili Anvar, Nazanin, Lin, Chenchu, Ma, Xingdi, Wilson, Lori L., Steger, Ryan, Sangree, Annabel K., Colic, Medina, Wang, Sidney H., Doench, John G., Hart, Traver

“…Genetic interactions mediate the emergence of phenotype from genotype, but technologies for combinatorial genetic perturbation in mammalian cells are…”
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Association between Interleukin 16 Gene Polymorphisms (rs1131445, rs4072111) and Late Onset of Alzheimer’s Disease in Iranian Patients by Esmaeili Anvar, Nazanin, Bazazzadegan, Niloofar, Ohadi, Mina, Kamali, Kourosh, Khorram Khorshid, Hamidreza

“…Objectives: Alzheimer's disease is the most common kind of dementia in the old age, and its incidenceincreases with age. Previous studies have shown that…”
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Association of Transforming Growth Factor Alpha Polymorphisms with Nonsyndromic Cleft Lip and Palate in Iranian Population by Ebadifar, Asghar, Hamedi, Roya, Khorram Khorshid, Hamid Reza, Saliminejad, Kioomars, Kamali, Koorosh, Aghakhani Moghadam, Fatemeh, Esmaeili Anvar, Nazanin, Ameli, Nazilla

“…Cleft lip with or without cleft palate (CL/P) is one of the most common congenital anomalies and the etiology of orofacial clefts is multifactorial…”
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DDDR-41. A GENOME-WIDE CRISPR/CAS9 SCREEN IN GLIOBLASTOMA STEM CELLS UNVEILS SYNTHETIC LETHAL INTERACTIONS AND RESISTANCE MECHANISMS OF JIN001, A BLOOD-BRAIN BARRIER-PENETRANT HSP90 INHIBITOR by Chen, Xiaohua, Anvar, Nazanin Esmaeili, Colic, Medina, Xu, Jihong, Liang, Jiyong, Sharma, Pratibha, Huo, Longfei, Sugur, Harsha S, Hart, Traver, Puduvalli, Vinay K

“…Glioblastomas (GBMs) are aggressive brain tumors characterized by extensive genetic heterogeneity and therapeutic resistance. Heat shock protein 90 (Hsp90) is…”
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The androgen receptor is a therapeutic target in desmoplastic small round cell sarcoma by Lamhamedi-Cherradi, Salah-Eddine, Maitituoheti, Mayinuer, Menegaz, Brian A., Krishnan, Sandhya, Vetter, Amelia M., Camacho, Pamela, Wu, Chia-Chin, Beird, Hannah C., Porter, Robert W., Ingram, Davis R., Ramamoorthy, Vandhana, Mohiuddin, Sana, McCall, David, Truong, Danh D., Cuglievan, Branko, Futreal, P. Andrew, Velasco, Alejandra Ruiz, Anvar, Nazanin Esmaeili, Utama, Budi, Titus, Mark, Lazar, Alexander J., Wang, Wei-Lien, Rodriguez-Aguayo, Cristian, Ratan, Ravin, Livingston, J. Andrew, Rai, Kunal, MacLeod, A. Robert, Daw, Najat C., Hayes-Jordan, Andrea, Ludwig, Joseph A.

“…Desmoplastic small round cell tumor (DSRCT) is an aggressive, usually incurable sarcoma subtype that predominantly occurs in post-pubertal young males. Recent…”
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Abstract 5972: Therapeutic modulation of rock overcomes metabolic adaption to oxphos inhibition and suppresses tumor growth by Blazanin, Nicholas, Liang, Xiaobing, Mahmud, Iqbal, Kim, Eiru, Tan, Lin, Anvar, Nazanin Esmaeili, Chan, Waikin, Ha, Min Jin, Minelli, Rosalba, Peoples, Michael, Lorenzi, Philip, Hart, Travar, Lissanu, Yonathan

“…Lung cancer is the top cause of cancer mortality. Despite recent advances, the majority of patients with lung cancer still lack effective therapeutic options,…”
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Association between polymorphisms in Interleukin-16 gene and risk of late-onset Alzheimer's disease by Anvar, Nazanin Esmaeili, Saliminejad, Kioomars, Ohadi, Mina, Kamali, Koorosh, Daneshmand, Parvaneh, Khorshid, Hamid Reza Khorram

“…Abstract Cytokines play important roles in the inflammation pathways. Alzheimer's disease (AD) is an inflammatory disease, and it is suggested that cytokines…”
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BMP2 and BMP4 variations and risk of non-syndromic cleft lip and palate by Saket, Mitra, Saliminejad, Kioomars, Kamali, Koorosh, Moghadam, Fatemeh Aghakhani, Anvar, Nazanin Esmaeili, Khorram Khorshid, Hamid Reza, MD, PhD

“…Highlights • Non-syndromic cleft lip/palate arises from the interaction of environmental and genetic factors. • We investigate the association of BMP2 and BMP4…”
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Abstract 3241: Elevated H3K27 trimethylation mediates adaptation to DNA demethylation in BRAFV600E-mutated colorectal cancer by Lee, Hey Min, Saw, Ajay Kumar, Morris, Van Karlyle, Singh, Anand Kamal, Napolitano, Stefania, Sorokin, Alexey, Marie, Preeti Kanikarla, Coker, Oluwadara, Villarreal, Oscar Eduardo, Anvar, Nazanin Esmaeili, Rai, Kunal, Kopetz, Scott

“…Background: BRAFV600E in colorectal cancer (CRC) defines a unique subgroup of patients with poor prognosis and scarcely benefit from BRAF inhibitor-based…”
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