Search Results - "Antunes, Vagner Roberto"
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Nutraceuticals in the management of autonomic function and related disorders: A comprehensive review
Published in Pharmacological research (01-10-2024)“…Nutraceuticals have been described as phytocomplexes when derived from foods of plant origin or a pool of secondary metabolites when derived from foods of…”
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Biofunctionalization of surfaces to minimize undesirable effects in cardiovascular assistance devices
Published in Artificial organs (01-02-2024)“…Background The reactivity of blood with non‐endothelial surface is a challenge for long‐term Ventricular Assist Devices development, usually made with pure…”
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Salt-induced sympathoexcitation involves vasopressin V1a receptor activation in the paraventricular nucleus of the hypothalamus
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-12-2015)“…A high-salt diet can lead to hydromineral imbalance and increases in plasma sodium and osmolality. It is recognized as one of the major contributing factors…”
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Effects of Psidium guajava L. leaves extract on blood pressure control and IL-10 production in salt-dependent hypertensive rats
Published in Biomedicine & pharmacotherapy (01-11-2022)“…Psidium guajava (guava) leaves extract displays anti-hypertensive properties by mechanisms not yet fully understood. Here, we investigated whether sympathetic…”
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Chronic high-sodium diet intake after weaning lead to neurogenic hypertension in adult Wistar rats
Published in Scientific reports (18-07-2017)“…In this study, we investigated some mechanisms involved in sodium-dependent hypertension of rats exposed to chronic salt (NaCl) intake from weaning until adult…”
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Insulin Activates Parasympathetic Hepatic-related PVN Neurons Through mTOR signaling
Published in Physiology (Bethesda, Md.) (01-05-2023)“…Abstract only Paraventricular nucleus of hypothalamus (PVN) is an important brain region regulating a diversity of autonomic functions, such as hepatic glucose…”
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Exercise-induced neuroplasticity in autonomic nuclei restores the cardiac vagal tone and baroreflex dysfunction in aged hypertensive rats
Published in Journal of applied physiology (1985) (2024)“…Aging is accompanied by considerable deterioration of homeostatic systems, such as autonomic imbalance characterized by heightened sympathetic activity, lower…”
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Central action of CART induces neuronal activation in the paraventricular and dorsomedial hypothalamus of diet-induced obese and lean mice
Published in Neuroscience letters (01-11-2018)“…•The central action of CART selective activates the PVN and DMH of obese mice than of lean mice.•CART is a putative link between the metabolic and…”
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Exercise Training and Chemogenetic Activation of the Dorsal Motor Nucleus of the Vagus Rescue the Changes in the Hepatic Vein Glucose Concentration by Central Action of Insulin in SHR
Published in The FASEB journal (01-05-2022)“…The Dorsal Motor Nucleus of the Vagus (DMNV) is the main parasympathetic output from CNS as part of the brain‐liver axis that participates on glucose…”
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Short exposure to high salt in drinking solution leads to a cardiovascular phenotype of hypertension without changes in the blood volume of rats
Published in Experimental physiology (01-03-2023)“…New Findings What is the central question of this study? Is the cardiovascular phenotype of high blood pressure observed in rats salt loaded with 2% NaCl in…”
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Vasopressin Gene Expression is Differently Regulated at the PVN Level of Salt‐loaded Wistar and SHR
Published in The FASEB journal (01-04-2016)“…Abstract only It is known that osmotic challenges leads to an increase in blood pressure that is associate with a simpathoexcitatory component; moreover, the…”
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The gut-brain axis and sodium appetite: Can inflammation-related signaling influence the control of sodium intake?
Published in Appetite (01-08-2022)“…Sodium is the main cation present in the extracellular fluid. Sodium and water content in the body are responsible for volume and osmotic homeostasis through…”
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Protein disulfide isomerase-mediated transcriptional upregulation of Nox1 contributes to vascular dysfunction in hypertension
Published in Journal of hypertension (01-06-2024)“…Nox1 signaling is a causal key element in arterial hypertension. Recently, we identified protein disulfide isomerase A1 (PDI) as a novel regulatory protein…”
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ATP‐induced sympathoexcitation involves purinergic and glutamatergic mechanisms in the RVLM‐projecting PVN neurons
Published in The FASEB journal (01-04-2013)“…Abstract only We have shown that ATP applied into the PVN induces a dose‐dependent increase in the lumbar sympathetic nerve activity (LSNA), such effect…”
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Exercise training rescues the electrical activity of liver‐projecting DMNV neurones in response to oxytocin in spontaneously hypertensive rats
Published in Journal of neuroendocrinology (01-05-2021)“…A neural circuit between the paraventricular nucleus of the hypothalamus (PVN) and the dorsal motor nucleus of the vagus (DMNV) constitutes part of an…”
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Ectonucleotidases in the Hypothalamus of Salt‐Induced Hypertensive Rats: Transcriptional Profile and functional implications
Published in The FASEB journal (01-04-2018)“…Ectonucleotidases consist of families of nucleotide metabolizing enzymes that hydrolyze extracellular nucleotides, such as ATP, to nucleosides. At the CNS…”
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Psidium guajava leaves extract alters colonic microbiome composition and reduces intestinal sodium absorption in rats exposed to a high-sodium diet
Published in Journal of pharmacy and pharmacology (07-11-2024)“…High sodium intake is a major risk factor for hypertension and renal diseases. Previous studies have shown that a suspension of ethanolic extract of Psidium…”
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Antihypertensive effect of a nanoemulsion of baccharis dracunculifolia leaves extract in sodium-dependent hypertensive rats
Published in Natural product research (08-09-2024)“…(DC) is an important botanical source of Brazilian green propolis and have many compounds with potential antihypertensive activity. However, little is known…”
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Evaluation of PI3K expression and its interaction with angiotensin II on central autonomic nuclei of hypertensive animals
Published in The FASEB journal (01-04-2010)“…There is evidence that PI3K protein is directly linked to the intracellular signaling of the angiotensin II (ANG II) pathways (via AT1 receptors) that act as a…”
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Swimming training improves cardiovascular autonomic dysfunctions and prevents renal damage in rats fed a high‐sodium diet from weaning
Published in Experimental physiology (01-02-2021)“…New Findings What is the central question of this study? How does swimming exercise training impact hydro‐electrolytic balance, renal function, sympathetic…”
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