Search Results - "Antunes, Lusânia"

Cocoplum (Chrysobalanus icaco L.) anthocyanins exert anti-inflammatory activity in human colon cancer and non-malignant colon cells by Venancio, Vinicius P, Cipriano, Paula A, Kim, Hyemee, Antunes, Lusânia M G, Talcott, Stephen T, Mertens-Talcott, Susanne U

“…Cocoplum (Chrysobalanus icaco L.) (CP) is an anthocyanin-rich fruit found in tropical areas around the globe. CP polyphenols are associated with beneficial…”
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Green recovery and application of berry anthocyanins in functional gummies: Stability study, plasma and cellular antioxidant and anti-inflammatory activity by Mohammadi, Nima, Franchin, Marcelo, Girotto Pressete, Carolina, Maria Greggi Antunes, Lusânia, Granato, Daniel

“…[Display omitted] •Optimal extraction: blackberry at 325 W, 7.5 min; elderberry at 400 W, 5 min.•Elderberry extracts had higher phenolic and antioxidant…”
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Gold-Coated Superparamagnetic Iron Oxide Nanoparticles Attenuate Collagen-Induced Arthritis after Magnetic Targeting by Carneiro, Maria Fernanda Hornos, Machado, Ana Rita T., Antunes, Lusânia M. G., Souza, Talita E., Freitas, Victor A., Oliveira, Luiz C. A., Rodrigues, Jairo L., Pereira, Marcio C., Barbosa, Fernando

“…The aim of the study was to evaluate if gold-coated superparamagnetic iron oxide nanoparticles (AuSPION) magnetic-targeted to the arthritic articulation of…”
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Cyto and genotoxicity of gold nanoparticles in human hepatocellular carcinoma and peripheral blood mononuclear cells by Paino, Iêda Maria Martinez, Marangoni, Valéria Spolon, de Oliveira, Rita de Cássia Silva, Antunes, Lusânia Maria Greggi, Zucolotto, Valtencir

“…[Display omitted] ► The geno- and cytotoxicity of gold nanoparticles in cancer and healthy cells were investigated. ► The reactive oxygen species (ROS)…”
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Genotoxic and mutagenic effects of erythrosine B, a xanthene food dye, on HepG2 cells by Chequer, Farah Maria Drumond, Venâncio, Vinícius de Paula, Bianchi, Maria de Lourdes Pires, Antunes, Lusânia Maria Greggi

“…► Erythrosine B increased both Tail Moment and Tail Intensity on HepG2 cells at 50 and 70μgmL−1. ► Erythrosine B was mutagenic on HepG2 cells by…”
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CR-LAAO, an L-amino acid oxidase from Calloselasma rhodostoma venom, as a potential tool for developing novel immunotherapeutic strategies against cancer by Costa, Tássia R., Menaldo, Danilo L., Zoccal, Karina F., Burin, Sandra M., Aissa, Alexandre F., Castro, Fabíola A. de, Faccioli, Lúcia H., Greggi Antunes, Lusânia M., Sampaio, Suely V.

“…L-amino acid oxidases from snake venoms have been described to possess various biological functions. In this study, we investigated the inflammatory responses…”
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Transcriptome and DNA methylation changes modulated by sulforaphane induce cell cycle arrest, apoptosis, DNA damage, and suppression of proliferation in human liver cancer cells by dos Santos, Patrick Wellington da Silva, Machado, Ana Rita Thomazela, De Grandis, Rone Aparecido, Ribeiro, Diego Luis, Tuttis, Katiuska, Morselli, Marco, Aissa, Alexandre Ferro, Pellegrini, Matteo, Antunes, Lusânia Maria Greggi

“…Abnormal epigenetic alterations are one of the keystones of cancer development. Epigenetic targeting drugs have become a promising and effective cancer therapy…”
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Antitumor potential of the myotoxin BthTX-I from Bothrops jararacussu snake venom: evaluation of cell cycle alterations and death mechanisms induced in tumor cell lines by Prinholato da Silva, Cássio, Costa, Tássia R, Paiva, Raquel M Alves, Cintra, Adélia C O, Menaldo, Danilo L, Antunes, Lusânia M Greggi, Sampaio, Suely V

“…Phospholipases A2 (PLA2s) are abundant components of snake venoms that have been extensively studied due to their pharmacological and pathophysiological…”
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Immunomodulatory actions and epigenetic alterations induced by proteases from Bothrops snake venoms in human immune cells by Menaldo, Danilo L., Costa, Tássia R., Ribeiro, Diego L., Zambuzi, Fabiana A., Antunes, Lusânia M.G., Castro, Fabíola A., Frantz, Fabiani G., Sampaio, Suely V.

“…The aim of this study was to evaluate the immunomodulatory effects of two toxins from Bothrops snake venoms (the P–I metalloprotease Batroxase and the…”
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Low levels of methylmercury induce DNA damage in rats: protective effects of selenium by Grotto, Denise, Barcelos, Gustavo R. M., Valentini, Juliana, Antunes, Lusânia M. G., Angeli, José Pedro F., Garcia, Solange C., Barbosa, Fernando

“…In this study we examined the possible antigenotoxic effect of selenium (Se) in rats chronically exposed to low levels of methylmercury (MeHg) and the…”
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Epigenetic changes induced in mice liver by methionine-supplemented and methionine-deficient diets by Aissa, Alexandre Ferro, Tryndyak, Volodymyr P., de Conti, Aline, Rita Thomazela Machado, Ana, Tuttis, Katiuska, da Silva Machado, Carla, Hernandes, Lívia Cristina, Wellington da Silva Santos, Patrick, Mara Serpeloni, Juliana, P Pogribny, Igor, Antunes, Lusânia Maria Greggi

“…A diet deficient in donors of methyl group, such as methionine, affects DNA methylation and hepatic lipid metabolism. Methionine also affects other epigenetic…”
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Effects of crotamine in human prostate cancer cell line by Alberghini-dos-Santos, João Victor, Sanchez, Caroline Andolfato, Bordon, Karla de Castro Figueiredo, Pucca, Manuela Berto, Antunes, Lusânia Maria Greggi, Arantes, Eliane Candiani, Oliveira, Isadora Sousa de

“…Our study presents the anticancer potential of crotamine from Crotalus durissus terrificus in human prostate cancer cell line DU-145. Crotamine isolation was…”
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Evaluation of the genotoxicity of Crotalus durissus terrificus snake venom and its isolated toxins on human lymphocytes by Marcussi, Silvana, Santos, Paulo R.S., Menaldo, Danilo L., Silveira, Lucas B., Santos-Filho, Norival A., Mazzi, Maurício V., da Silva, Saulo L., Stábeli, Rodrigo G., Antunes, Lusânia M. Greggi, Soares, Andreimar M.

“…In the present study, experiments were carried out to evaluate the mutagenic potential and genotoxic effects of Crotalus durissus terrificus snake venom and…”
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Adaptive epigenetic response of glutathione (GSH)-related genes against lead (Pb)-induced toxicity, in individuals chronically exposed to the metal by Devóz, Paula Pícoli, Reis, Mariana Bisarro dos, Gomes, Willian Robert, Maraslis, Flora Troina, Ribeiro, Diego Luis, Antunes, Lusânia Maria Greggi, Batista, Bruno Lemos, Grotto, Denise, Reis, Rui Manuel, Barbosa Jr, Fernando, Barcelos, Gustavo Rafael Mazzaron

“…It is well known that one of the most outstanding adverse effects related to lead (Pb) exposure is oxidative stress; moreover, recent findings suggest that…”
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Cocoplum (Chrysobalanus icaco L.) decreases doxorubicin-induced DNA damage and downregulates Gadd45a, Il-1β, and Tnf-α in vivo by Venancio, Vinicius Paula, Almeida, Mara Ribeiro, Antunes, Lusânia Maria Greggi

“…DNA damage and inflammation are promising targets in disease prevention studies. Since these pathways have shown to be modulated by dietary components,…”
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Curcumin reduces cisplatin-induced neurotoxicity in NGF-differentiated PC12 cells by Mendonça, Leonardo Meneghin, da Silva Machado, Carla, Correia Teixeira, Cristiane Cardoso, Pedro de Freitas, Luis Alexandre, Pires Bianchi, Maria de Lourdes, Greggi Antunes, Lusânia Maria

“…► Curcumin reduced cisplatin-induced neurite toxicity in a PC12 cell model by up to 50%. ► Curcumin's neuroprotective effects did not involve suppression of…”
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Synephrine and caffeine combination promotes cytotoxicity, DNA damage and transcriptional modulation of apoptosis-related genes in human HepG2 cells by Leão, Tainá Keiller, Ribeiro, Diego Luís, Machado, Ana Rita Thomazela, Costa, Tássia Rafaela, Sampaio, Suely Vilela, Antunes, Lusânia Maria Greggi

“…•This study examined toxicogenomic effects of Synephrine (SN) and Caffeine (CAF).•SN/CAF combination induced cytotoxicity, cell death, and DNA damage in HepG2…”
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Sulforaphane Combined with Vitamin D Induces Cytotoxicity Mediated by Oxidative Stress, DNA Damage, Autophagy, and JNK/MAPK Pathway Modulation in Human Prostate Tumor Cells by Tuttis, Katiuska, Machado, Ana Rita Thomazela, Santos, Patrick Wellington da Silva, Antunes, Lusânia Maria Greggi

“…Prostate cancer ranks second in incidence worldwide. To date, there are no available therapies to effectively treat advanced and metastatic prostate cancer…”
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Caffeic acid and chlorogenic acid cytotoxicity, genotoxicity and impact on global DNA methylation in human leukemic cell lines by Hernandes, Lívia Cristina, Machado, Ana Rita Thomazela, Tuttis, Katiuska, Ribeiro, Diego Luís, Aissa, Alexandre Ferro, Dévoz, Paula Pícoli, Antunes, Lusânia Maria Greggi

“…Dietary phenolic compounds such as caffeic and chlorogenic acid exert an antiproliferative effect and modulate the gene-specific DNA methylation status in…”
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CR-LAAO causes genotoxic damage in HepG2 tumor cells by oxidative stress by Costa, Tássia R., Amstalden, Martin K., Ribeiro, Diego L., Menaldo, Danilo L., Sartim, Marco A., Aissa, Alexandre F., Antunes, Lusânia M.G., Sampaio, Suely V.

“…•CR-LAAO possesses higher binding affinity to HepG2 tumor cells than to PBMC.•CR-LAAO significantly increased intracellular levels of ROS only in HepG2 tumor…”
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