Search Results - "Antunes, Flávia"
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Advantages of modeling the urban heat island intensity: A tool for implementing nature-based solutions
Published in Sustainable cities and society (01-03-2024)“…•Random forest models simulate scenarios considering nature-based solutions (NBS).•All models achieved a high explanatory power (R2 ≥ 0.82).•NBS included Local…”
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Analgesic effects of the CTK 01512-2 toxin in different models of orofacial pain in rats
Published in Pharmacological reports (01-06-2020)“…Orofacial pain is clinically challenging, having therapeutic failures and side effects. This study evaluated the antinociceptive activities of the CTK 01512-2…”
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3
Nitrogen stress and the expression of asparagine synthetase in roots and nodules of soybean (Glycine max)
Published in Physiologia Plantarum (København. 1948) (01-08-2008)“…The difficulty of assaying asparagine synthetase (AS) (EC 6.3.5.4) activity in roots of soybean has been circumvented by measuring expression of the AS genes…”
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Assessment of Conventional Full-Scale Treatment for the Removal of Endocrine Disruptors and Pharmaceuticals Present in the Tibagi River (Paraná State, Brazil)
Published in Frontiers in environmental science (02-09-2021)“…The concentrations of 25 pharmaceuticals and endocrine disruptors were monitored in the water coming from the Tibagi River (State of Paraná, Brazil) and in a…”
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Coprodução em Conselhos Municipais de Educação: possibilidades para a coprodução do controle
Published in Linhas críticas (02-06-2023)“…Este artigo tem como objetivo examinar teoricamente as possibilidades de atuação dos Conselhos Municipais da Educação (CMEs) na coprodução do bem público, por…”
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UnCRMPing Nav1.7 to treat trigeminal neuropathic pain
Published in Pain (Amsterdam) (01-03-2024)Get full text
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Differential regulation of Cav3.2 and Cav2.2 calcium channels by CB1 receptors and cannabidiol
Published in British journal of pharmacology (01-06-2023)“…Background and Purpose Cannabinoids are a promising therapeutic avenue for chronic pain. However, clinical trials often fail to report analgesic efficacy of…”
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Icariside II, a Prenyl-Flavonol, Alleviates Inflammatory and Neuropathic Pain by Inhibiting T‑Type Calcium Channels and USP5-Cav3.2 Interactions
Published in ACS chemical neuroscience (17-05-2023)“…Cav3.2 channels play an important role in the afferent nociceptive pathway, which is responsible for both physiological and pathological pain transmission…”
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Neuroprotective effects of the CTK 01512-2 toxin against neurotoxicity induced by 3-nitropropionic acid in rats
Published in Neurotoxicology (Park Forest South) (01-12-2021)“…[Display omitted] •CTK 01512-2 maintained the glucose uptake levels in the rats' brains.•CTK 01512-2 ameliorated the behavioral deficits in the 3-NP treated…”
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Contribution of T‐type calcium channel isoforms to cold and mechanical sensitivity in naïve and oxaliplatin‐treated mice of both sexes
Published in British journal of pharmacology (01-12-2024)“…Background and Purpose The chemotherapy agent oxaliplatin can give rise to oxaliplatin‐induced peripheral neuropathy (OIPN). Here, we investigated whether…”
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Adaptogenic effects of curcumin on depression induced by moderate and unpredictable chronic stress in mice
Published in Behavioural brain research (05-02-2021)“…•Curcumin 50 mg/kg had anxiolytic effects on the non-stressed animals.•Curcumin treatments prevented depressive-like behavior induced by CUMS.•Curcumin…”
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Evaluation of lipolysis and toxicological parameters of low-level laser therapy at different wavelengths and doses in the abdominal subcutaneous tissue
Published in Lasers in medical science (01-03-2022)“…Investigate the effects of low-level lasers therapy (LLLT) aiming abdominal lipolysis. Female Wistar rats received applications of LLLT directly in the…”
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13
Differential regulation of Ca v 3.2 and Ca v 2.2 calcium channels by CB 1 receptors and cannabidiol
Published in British journal of pharmacology (01-06-2023)“…Cannabinoids are a promising therapeutic avenue for chronic pain. However, clinical trials often fail to report analgesic efficacy of cannabinoids. Inhibition…”
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Journal Article -
14
Development of Tetrahydroquinoline-Based Inhibitors for Chronic Pain
Published in ACS chemical neuroscience (08-10-2024)“…Chronic pain affects a substantial portion of the population, posing a significant health challenge. Current treatments often come with limitations and side…”
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Recombinant peptide derived from the venom the Phoneutria nigriventer spider relieves nociception by nerve deafferentation
Published in Neuropeptides (Edinburgh) (01-02-2020)“…The avulsion of nerve roots of the brachial plexus that is commonly seen in motorcycle accidents is a type of neuropathy due to deafferentation. This type of…”
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Phα1β is a Promising Neuroprotective Peptide from the Phoneutrianigriventer‘Armed’ Spider
Published in International journal of peptide research and therapeutics (01-03-2022)“…Phα1β and its recombinant form CTK 01512-2 are peptides. They are derived from the venom of the Phoneutria nigriventer ‘armed’ spider. They display biological…”
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The effects of Brazilian chitosan-based biomaterials on wound healing in rats
Published in Tissue & cell (01-04-2021)“…[Display omitted] •Microcrystalline chitosan biomembranes showed better healing aspects.•Epithelization and keratinization occurred under the biomaterial crust…”
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Cultivo in vitro de plântulas de abacaxizeiro com uso de filtros, ventilação artificial e sacarose
Published in Agro@mbiente on-line (06-07-2015)“…Uma alternativa para a produção de mudas de qualidade é a utilização de sistemas de propagação in vitro. Porém, o ambiente de cultivo convencional in vitro é…”
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Journal Article -
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Acute Toxicity of the Recombinant and Native Phα1β Toxin: New Analgesic from Phoneutria nigriventer Spider Venom
Published in Toxins (12-12-2018)“…Phα1β, a purified peptide from the venom of the spider , and its recombinant form CTK 01512-2 are voltage-dependent calcium channel (Ca ) blockers of types N,…”
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Anti-inflammatory effects of a topical emulsion containing Helianthus annuus oil, glycerin, and vitamin B3 in mice
Published in Journal of pharmaceutical investigation (01-03-2021)“…Purpose The pharmaceutical industry has been searching for drugs that aim at the prevention, the protection, and the recovery of the skin. Thus, the aim of…”
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