Search Results - "Antunes, Bruno César"

Forty Years of the Description of Brown Spider Venom Phospholipases-D by Gremski, Luiza Helena, da Justa, Hanna Câmara, da Silva, Thaís Pereira, Polli, Nayanne Louise Costacurta, Antunes, Bruno César, Minozzo, João Carlos, Wille, Ana Carolina Martins, Senff-Ribeiro, Andrea, Arni, Raghuvir Krishnaswamy, Veiga, Silvio Sanches

“…Spiders of the genus , popularly known as Brown spiders, are considered a serious public health issue, especially in regions of hot or temperate climates, such…”
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Brown Spiders' Phospholipases-D with Potential Therapeutic Applications: Functional Assessment of Mutant Isoforms by da Silva, Thaís Pereira, de Castro, Fernando Jacomini, Vuitika, Larissa, Polli, Nayanne Louise Costacurta, Antunes, Bruno César, Bóia-Ferreira, Marianna, Minozzo, João Carlos, Mariutti, Ricardo Barros, Matsubara, Fernando Hitomi, Arni, Raghuvir Krishnaswamy, Wille, Ana Carolina Martins, Senff-Ribeiro, Andrea, Gremski, Luiza Helena, Veiga, Silvio Sanches

“…Phospholipases-D (PLDs) found in spiders' venoms are responsible for the dermonecrosis triggered by envenomation. PLDs can also induce other local and systemic…”
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The Health Status of Horses Used for at Least Six Complete Cycles of Loxoscelic Antivenom Production by Miranda, Ana Luísa Soares de, Antunes, Bruno Cesar, Minozzo, João Carlos, Lima, Sabrina de Almeida, Botelho, Ana Flávia Machado, Campos, Marco Túlio Gomes, Chávez-Olórtegui, Carlos, Soto-Blanco, Benito

“…Antivenom production against venom relies on horses being immunized and bled for plasma harvest. One horse can partake in several cycles of antivenom…”
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Clinical Effects of the Immunization Protocol Using Loxosceles Venom in Naïve Horses by Miranda, Ana Luísa Soares de, Antunes, Bruno Cesar, Minozzo, João Carlos, Lima, Sabrina de Almeida, Botelho, Ana Flávia Machado, Campos, Marco Túlio Gomes, Chávez-Olórtegui, Carlos Delfin, Soto-Blanco, Benito

“…Bites of brown spiders ( spp.) are responsible for dermonecrotic lesions and potentially systemic envenoming that can lead to death. The only effective therapy…”
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Production and Functional Evaluation of Anti- Loxosceles Sera Raised by Immunizations of Rabbits with Mutated Recombinant Phospholipases-D by Antunes, Bruno Cesar, Polli, Nayanne Louise Costacurta, Schluga, Pedro Henrique de Caires, Silva, Thais Pereira da, Wille, Ana Carolina Martins, Locatelli-Dittrich, Rosangela, Souza, Giovana Scuissiatto de, Matsubara, Fernando Hitomi, Minozzo, João Carlos, Senff-Ribeiro, Andrea, Gremski, Luiza Helena, Veiga, Silvio Sanches

“…Loxoscelism is the clinical condition triggered after the bite of spiders of the genus . The main species involved in accidents in South America are , and …”
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Prospective Use of Brown Spider Venom Toxins as Therapeutic and Biotechnological Inputs by Gremski, Luiza Helena, Matsubara, Fernando Hitomi, Polli, Nayanne Louise Costacurta, Antunes, Bruno Cesar, Schluga, Pedro Henrique de Caires, Justa, Hanna Câmara da, Minozzo, João Carlos, Wille, Ana Carolina Martins, Senff-Ribeiro, Andrea, Veiga, Silvio Sanches

“…Brown spider (genus Loxosceles ) venoms are mainly composed of protein toxins used for predation and defense. Bites of these spiders most commonly produce a…”
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Novel insights into the application of recombinant mutated phospholipases D as antigens for developing new strategies against Loxoscelism by Polli, Nayanne Louise Costacurta, Ferreira, Maria Eduarda de Fraga, Schluga, Pedro Henrique Caires, Antunes, Bruno Cesar, Justa, Hanna Câmara da, Theodoro, João Lucas, Zazula, Matheus Felipe, Naliwaiko, Katya, Minozzo, João Carlos, Senff-Ribeiro, Andrea, Wille, Ana Carolina Martins, Veiga, Silvio Sanches, Gremski, Luiza Helena

“…•Neutralization of cutaneous and systemic loxoscelism was assessed.•The sphingomyelinase activity of Loxosceles venoms was neutralized.•Number of immunizations…”
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A protective vaccine against the toxic activities following Brown spider accidents based on recombinant mutated phospholipases D as antigens by Polli, Nayanne Louise Costacurta, Justa, Hanna Camara da, Antunes, Bruno Cesar, Silva, Thais Pereira da, Dittrich, Rosangela Locatelli, de Souza, Giovana Scuissiatto, Wille, Ana Carolina Martins, Matsubara, Fernando Hitomi, Minozzo, João Carlos, Mariutti, Ricardo Barros, Arni, Raghuvir Krishnaswamy, Senff-Ribeiro, Andrea, Veiga, Silvio Sanches, Gremski, Luiza Helena

“…Accidents involving Brown spiders are reported throughout the world. In the venom, the major toxins involved in the deleterious effects are phospholipases D…”
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Production of a novel recombinant brown spider hyaluronidase in baculovirus-infected insect cells by De-Bona, Elidiana, Chaves-Moreira, Daniele, Batista, Thiago Beltrami Dias, Justa, Hanna Câmara da, Rossi, Gustavo Rodrigues, Antunes, Bruno Cesar, Matsubara, Fernando Hitomi, Minozzo, João Carlos, Wille, Ana Carolina Martins, Veiga, Silvio Sanches, Senff-Ribeiro, Andrea, Gremski, Luiza Helena

“…•Recombinant brown spider hyaluronidase LiHyal2 isoform is a glycosidase enzyme.•LiHyal2 is the first recombinant brown spider enzyme produced by insect…”
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Protective response against toxic effects of Loxosceles spider venoms using recombinant mutated phospholipases-D as antigens by Costacurta Polli, Nayanne Louise, Antunes, Bruno Cesar, Da Silva, Thais Pereira, Vuitika, Larissa, Da Justa, Hanna Câmara, Minozzo, João Carlos, Veiga, Silvio Sanches, Gremski, Luiza Helena

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Next-generation sequencing reveals new insights about gene usage and CDR-H3 composition in the horse antibody repertoire by Manso, Taciana Conceição, Groenner-Penna, Michele, Minozzo, João Carlos, Antunes, Bruno Cesar, Ippolito, Gregory C., Molina, Franck, Felicori, Liza F.

“…•IGH predominant genes are IGHV2S3, IGHD18S1, and IGHJ1S5 in non-immunized horses.•IGL predominant genes are IGLV8S1 and IGLJ5S1 in adult non-immunized…”
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Phospholipase D from venoms of Loxosceles spiders: a structural, biochemical and biological comparison by Vuitika, Larissa, Graeff, Zelinda Schemczssen, Muriutti, Ricardo Barros, Moraes, Fábio Rogério, Matsubara, Fernando Hitomi, Da Justa, Hanna Câmara, Ferreira, Marianna Boia, De Castro, Fernando Jacomini, Antunes, Bruno Cesar, Minozzo, João Carlos, Gremski, Luiza Helena, Ribeiro, Andrea Senff, Arni, Raghuvir Krishnaswamy, Veiga, Silvio Sanches

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