Search Results - "Antov, Andrey"

Alternative activation of macrophages by IL‐4 requires SHIP degradation by Weisser, Shelley B., McLarren, Keith W., Voglmaier, Nicole, van Netten‐Thomas, Christina J., Antov, Andrey, Flavell, Richard A., Sly, Laura M.

“…Alternatively activated macrophages are critical in host defense against parasites and are protective in inflammatory bowel disease, but contribute to…”
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Community oncologists' perceptions and utilization of large-panel genomic tumor testing by Anderson, Eric C, Hinton, Alexandra C, Lary, Christine W, Fenton, Anny T H R, Antov, Andrey, Edelman, Emily, Helbig, Petra, Reed, Kate, Miesfeldt, Susan, Thomas, Christian A, Hall, Michael J, Roberts, J Scott, Rueter, Jens, Han, Paul K J

“…Large-panel genomic tumor testing (GTT) is an emerging technology with great promise but uncertain clinical value. Previous research has documented variability…”
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SHIP Represses the Generation of IL-3-Induced M2 Macrophages by Inhibiting IL-4 Production from Basophils by Kuroda, Etsushi, Ho, Victor, Ruschmann, Jens, Antignano, Frann, Hamilton, Melisa, Rauh, Michael J, Antov, Andrey, Flavell, Richard A, Sly, Laura M, Krystal, Gerald

“…There is a great deal of interest in determining what regulates the generation of classically activated (M1) vs alternatively activated (M2) macrophages…”
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Genome-matched treatments and patient outcomes in the Maine Cancer Genomics Initiative (MCGI) by Anderson, Eric C., DiPalazzo, John, Lucas, F. Lee, Hall, Michael J., Antov, Andrey, Helbig, Petra, Bourne, Jennifer, Graham, Leah, Gaitor, Lory, Lu-Emerson, Christine, Bradford, Leslie S., Inhorn, Roger, Sinclair, Sarah J., Brooks, Philip L., Thomas, Christian A., Rasmussen, Karen, Han, Paul K. J., Liu, Edison T., Rueter, Jens

“…Genomic tumor testing (GTT) is an emerging technology aimed at identifying variants in tumors that can be targeted with genomically matched drugs. Due to…”
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Requirement for AHNAK1-mediated calcium signaling during T lymphocyte cytolysis by Matza, Didi, Badou, Abdallah, Jha, Mithilesh K, Willinger, Tim, Antov, Andrey, Sanjabi, Shomyseh, Kobayashi, Koichi S, Marchesi, Vincent T, Flavell, Richard A

“…Cytolytic CD8⁺ T cells (CTLs) kill virally infected cells, tumor cells, or other potentially autoreactive T cells in a calcium-dependent manner. To date, the…”
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Autoimmunity as the Consequence of a Spontaneous Mutation in Rasgrp1 by Layer, Katrin, Lin, Guosheng, Nencion, Alessio, Hu, Wei, Schmucker, Adam, Antov, Andrey N., Li, Xiaoyu, Takamatsu, Satoshi, Chevassut, Timothy, Dower, Nancy A., Stang, Stacey L., Beier, David, Buhlmann, Janet, Bronson, Roderick T., Elkon, Keith B., Stone, James C., Van Parijs, Luk, Lim, Bing

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Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1 by Layer, Katrin, Lin, Guosheng, Nencioni, Alessio, Hu, Wei, Schmucker, Adam, Antov, Andrey N, Li, Xiaoyu, Takamatsu, Satoshi, Chevassut, Timothy, Dower, Nancy A, Stang, Stacey L, Beier, David, Buhlmann, Janet, Bronson, Roderick T, Elkon, Keith B, Stone, James C, Van Parijs, Luk, Lim, Bing

“…A mouse strain was identified with a recessive genetic lesion, which spontaneously developed a lymphoproliferative autoimmune syndrome exhibiting features of…”
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The different faces of Notch in T-helper-cell differentiation by Amsen, Derk, Flavell, Richard A, Antov, Andrey

“…Key Points Interleukin-12 (IL-12) and IL-4 are widely considered the main inducers of T helper 1 (T H 1)- and T H 2-cell differentiation, respectively…”
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CD4 T-cell differentiation and inflammatory bowel disease by Zenewicz, Lauren A, Antov, Andrey, Flavell, Richard A

“…Differentiation of naïve T cells leads to the generation of T-cell subsets, each possessing distinct cytokine expression profiles for serving different immune…”
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Direct Regulation of Gata3 Expression Determines the T Helper Differentiation Potential of Notch by Amsen, Derk, Antov, Andrey, Jankovic, Dragana, Sher, Alan, Radtke, Freddy, Souabni, Abdallah, Busslinger, Meinrad, McCright, Brent, Gridley, Thomas, Flavell, Richard A.

“…CD4 + T helper cells differentiate into T helper 1 (Th1) or Th2 effector lineages, which orchestrate immunity to different types of microbes. Both Th1 and Th2…”
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RETRACTED: Autoimmunity as the Consequence of a Spontaneous Mutation in Rasgrp1 by Layer, Katrin, Lin, Guosheng, Nencioni, Alessio, Hu, Wei, Schmucker, Adam, Antov, Andrey N., Li, Xiaoyu, Takamatsu, Satoshi, Chevassut, Timothy, Dower, Nancy A., Stang, Stacey L., Beier, David, Buhlmann, Janet, Bronson, Roderick T., Elkon, Keith B., Stone, James C., Van Parijs, Luk, Lim, Bing

“…This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been…”
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Differences in cancer patients’ and clinicians’ preferences for disclosure of uncertain genomic tumor testing results by Fenton, Anny T., Anderson, Eric C., Scharnetzki, Elizabeth, Reed, Kate, Edelman, Emily, Antov, Andrey, Rueter, Jens, Han, Paul K.J.

“…•A greater share of cancer patients than clinicians prefer disclosure of GTT results.•Patient preferences are less sensitive to uncertainty regarding…”
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Utilizing data from patient-derived xenograft mouse models of human tumors to inform clinical decision making in Molecular Tumor Boards (MTB) deliberations by Rueter, Jens, Airhart, Susan D., Bult, Carol J., Jocoy, Emily, Draheim, Kyle, Cheng, Mingshan, Antov, Andrey, Hesse, Andrew, Reddi, Honey, Haslem, Derrick S., Rhodes, Terence Duane, Nadauld, Lincoln

“…Abstract only e14660 Background: Molecular Tumor Boards (MTB) are often the critical decision-making step in identifying genome-guided treatments for patients…”
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The influence of uncertainty and uncertainty tolerance on attitudes and self-efficacy about genomic tumor testing by Anderson, Eric C., Hinton, Alexandra, Lary, Christine W., Strout, Tania, Antov, Andrey, Edelman, Emily, Helbig, Petra, Reed, Kate, Rueter, Jens, Han, Paul K.J.

“…Novel medical technologies, like large-panel genomic tumor testing (GTT), offer great promise but also substantial uncertainty regarding their clinical value…”
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Prospective study for comprehensive genomic profiling (GP) in cancer of unknown primary (CUP): Feasibility, molecular landscape, and clinical utility in current era by Raghav, Kanwal Pratap Singh, Willett, Anneleis, Huey, Ryan, Dhillon, Nishat, Modha, Jignesh, Matamoros, Aurelio Aurelio, Estrella, Jeannelyn, Sanghavi, Kunal, Antov, Andrey, Choquette, Linda, Statz, Cara, Kelly, Kevin, Rowe, Shannon, Liu, Edison T., Rueter, Jens, Kopetz, Scott, Overman, Michael J., Varadhachary, Gauri Rajani

“…Abstract only 834 Background: CUP presents a unique niche and challenge for application of GP. Absence of a primary limits consensus regarding site-directed…”
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Essential Role for STAT5 Signaling in CD25+CD4+ Regulatory T Cell Homeostasis and the Maintenance of Self-Tolerance by Antov, Andrey, Yang, Lili, Vig, Monika, Baltimore, David, Van Parijs, Luk

“…A population of CD25(+)CD4(+) regulatory T cells (T regs) functions to maintain immunological self tolerance by inhibiting autoreactive T cell responses…”
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The Maine Cancer Genomics Initiative: Implementing a Community Cancer Genomics Program Across an Entire Rural State by Rueter, Jens, Anderson, Eric C, Graham, Leah C, Antov, Andrey, Helbig, Petra, Gaitor, Lory, Bourne, Jennifer, Edelman, Emily, Reed, E Kate, Reddi, Honey V, Mockus, Susan, DiPalazzo, John, Lu-Emerson, Christine, Inhorn, Roger, Sinclair, Sarah J, Thomas, Christian A, Brooks, Philip L, Rasmussen, Karen, Han, Paul, Liu, Edison T

“…The Maine Cancer Genomics Initiative (MCGI) aimed to overcome patient- and provider-level barriers to using genomic tumor testing (GTT) in rural practices by…”
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The different faces of Notch in T-helper-cell differentiation by Amsen, Derk, Antov, Andrey, Flavell, Richard A

“…Interleukin-12 (IL-12) and IL-4 induce T helper 1 (T sub(H)1)- and T sub(H)2- cell differentiation, respectively, in vitro. However, not all T sub(H)1-cell…”
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Importance of the Notch and Wnt pathways for Th2 cells by Antov, Andrey

“…Development of asthma and allergies, as well as defense against extracellular parasites are controlled by a special subset of white blood cells, called T…”
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Importance of the Notch and Wnt pathways for Th2 cells by Antov, Andrey

“…Development of asthma and allergies, as well as defense against extracellular parasites are controlled by a special subset of white blood cells, called T…”
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