Search Results - "Antony, Aju"

Massively parallel single-cell B-cell receptor sequencing enables rapid discovery of diverse antigen-reactive antibodies by Goldstein, Leonard D., Chen, Ying-Jiun J., Wu, Jia, Chaudhuri, Subhra, Hsiao, Yi-Chun, Schneider, Kellen, Hoi, Kam Hon, Lin, Zhonghua, Guerrero, Steve, Jaiswal, Bijay S., Stinson, Jeremy, Antony, Aju, Pahuja, Kanika Bajaj, Seshasayee, Dhaya, Modrusan, Zora, Hötzel, Isidro, Seshagiri, Somasekar

“…Obtaining full-length antibody heavy- and light-chain variable regions from individual B cells at scale remains a challenging problem. Here we use…”
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Targeted editing of tomato carotenoid isomerase reveals the role of 5′ UTR region in gene expression regulation by Lakshmi Jayaraj, K., Thulasidharan, Nitu, Antony, Aju, John, Moni, Augustine, Rehna, Chakravartty, Navajeet, Sukumaran, Smitha, Uma Maheswari, M., Abraham, Sweety, Thomas, George, Lachagari, V. B. Reddy, Seshagiri, Somasekar, Narayanan, Subhash, Kuriakose, Boney

“…Key Message A deletion created by CRISPR/Cas9 system in the 5’ UTR of the carotenoid isomerase gene in tomato leads to downregulation of the gene resulting in…”
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Effect of molecular chaperones on the expression of Candida antarctica lipase B in Pichia pastoris by Samuel, Premsingh, Prasanna Vadhana, Ashok Kumar, Kamatchi, Ramakrishnan, Antony, Aju, Meenakshisundaram, Sankaranarayanan

“…One of the reasons for limited heterologous protein secretion in Pichia pastoris is the suboptimal folding conditions inside the cell. The Hsp70 and Hsp40…”
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Restricted epitope specificity determined by variable region germline segment pairing in rodent antibody repertoires by Hsiao, Yi-Chun, Chen, Ying-Jiun J, Goldstein, Leonard D, Wu, Jia, Lin, Zhonghua, Schneider, Kellen, Chaudhuri, Subhra, Antony, Aju, Bajaj Pahuja, Kanika, Modrusan, Zora, Seshasayee, Dhaya, Seshagiri, Somasekar, Hötzel, Isidro

“…Antibodies from B-cell clonal lineages share sequence and structural properties as well as epitope specificity. Clonally unrelated antibodies can similarly…”
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Embryonic lethality and defective mammary gland development of activator‐function impaired conditional knock‐in Erbb3V943R mice by Senger, Kate, Yuan, Wenlin, Sagolla, Meredith, Doerr, Jonas, Bolon, Brad, Ziai, James, Sun, Kai‐Hui, Warming, Soren, Roose‐Girma, Merone, Zhang, Na, Tam, Lucinda, Newman, Robert J., Chaudhuri, Subhra, Antony, Aju, Goldstein, Leonard D., Durinck, Steffen, Jaiswal, Bijay S., Lafkas, Daniel, Modrusan, Zora, Seshagiri, Somasekar

“…ERBB3 is a pseudokinase domain‐containing member of the ERBB family of receptor tyrosine kinases (RTKs). Following ligand binding, ERBB receptors homo‐ or…”
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The Indian cobra reference genome and transcriptome enables comprehensive identification of venom toxins by Suryamohan, Kushal, Krishnankutty, Sajesh P., Guillory, Joseph, Jevit, Matthew, Schröder, Markus S., Wu, Meng, Kuriakose, Boney, Mathew, Oommen K., Perumal, Rajadurai C., Koludarov, Ivan, Goldstein, Leonard D., Senger, Kate, Dixon, Mandumpala Davis, Velayutham, Dinesh, Vargas, Derek, Chaudhuri, Subhra, Muraleedharan, Megha, Goel, Ridhi, Chen, Ying-Jiun J., Ratan, Aakrosh, Liu, Peter, Faherty, Brendan, de la Rosa, Guillermo, Shibata, Hiroki, Baca, Miriam, Sagolla, Meredith, Ziai, James, Wright, Gus A., Vucic, Domagoj, Mohan, Sangeetha, Antony, Aju, Stinson, Jeremy, Kirkpatrick, Donald S., Hannoush, Rami N., Durinck, Steffen, Modrusan, Zora, Stawiski, Eric W., Wiley, Kristen, Raudsepp, Terje, Kini, R. Manjunatha, Zachariah, Arun, Seshagiri, Somasekar

“…Snakebite envenoming is a serious and neglected tropical disease that kills ~100,000 people annually. High-quality, genome-enabled comprehensive…”
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Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations by Pahuja, Kanika Bajaj, Nguyen, Thong T., Jaiswal, Bijay S., Prabhash, Kumar, Thaker, Tarjani M., Senger, Kate, Chaudhuri, Subhra, Kljavin, Noelyn M., Antony, Aju, Phalke, Sameer, Kumar, Prasanna, Mravic, Marco, Stawiski, Eric W., Vargas, Derek, Durinck, Steffen, Gupta, Ravi, Khanna-Gupta, Arati, Trabucco, Sally E., Sokol, Ethan S., Hartmaier, Ryan J., Singh, Ashish, Chougule, Anuradha, Trivedi, Vaishakhi, Dutt, Amit, Patil, Vijay, Joshi, Amit, Noronha, Vanita, Ziai, James, Banavali, Sripad D., Ramprasad, Vedam, DeGrado, William F., Bueno, Raphael, Jura, Natalia, Seshagiri, Somasekar

“…Deregulated HER2 is a target of many approved cancer drugs. We analyzed 111,176 patient tumors and identified recurrent mutations in HER2 transmembrane domain…”
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Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2 by Suryamohan, Kushal, Diwanji, Devan, Stawiski, Eric W., Gupta, Ravi, Miersch, Shane, Liu, Jiang, Chen, Chao, Jiang, Ying-Ping, Fellouse, Frederic A., Sathirapongsasuti, J. Fah, Albers, Patrick K., Deepak, Tanneeru, Saberianfar, Reza, Ratan, Aakrosh, Washburn, Gavin, Mis, Monika, Santhosh, Devi, Somasekar, Sneha, Hiranjith, G. H., Vargas, Derek, Mohan, Sangeetha, Phalke, Sameer, Kuriakose, Boney, Antony, Aju, Ustav Jr, Mart, Schuster, Stephan C., Sidhu, Sachdev, Junutula, Jagath R., Jura, Natalia, Seshagiri, Somasekar

“…COVID-19 is a respiratory illness caused by a novel coronavirus called SARS-CoV-2. The viral spike (S) protein engages the human angiotensin-converting enzyme…”
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Actionable activating oncogenic ERRB2/HER2 transmembrane and juxtamembrane domain mutations by Pahuja, Kanika Bajaj, Nguyen, Thong T., Jaiswal, Bijay S., Prabhash, Kumar, Thaker, Tarjani M., Senger, Kate, Chaudhuri, Subhra, Kljavin, Noelyn M., Antony, Aju, Phalke, Sameer, Kumar, Prasanna, Mravic, Marco, Stawiski, Eric W., Vargas, Derek, Durinck, Steffen, Gupta, Ravi, Khanna-Gupta, Arati, Trabucco, Sally E., Sokol, Ethan S., Hartmaier, Ryan J., Singh, Ashish, Chougule, Anuradha, Trivedi, Vaishakhi, Dutt, Amit, Patil, Vijay, Joshi, Amit, Noronha, Vanita, Ziai, James, Banavali, Sripad D, Ramprasad, Vedam, DeGrado, William F., Bueno, Raphael, Jura, Natalia, Seshagiri, Somasekar

“…Deregulated HER2 is a target of many approved cancer drugs. We analyzed 111,176 patient tumors and identified recurrent HER2 transmembrane domain (TMD) and…”
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Cloning and expression of recombinant human GMCSF from Pichia pastoris GS115--a progressive strategy for economic production by Srinivasa Babu, K, Pulicherla, Krishna Kanth, Antony, Aju, Meenakshisundaram, Sankaranarayanan

“…Human granulocyte-macrophage colony-stimulating factor (hGMCSF) is a proinflammatory cytokine and hematopoietic growth factor. Recombinant human…”
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Embryonic lethality and defective mammary gland development of activator-function impaired conditional knock-in Erbb3 V943R mice by Senger, Kate, Yuan, Wenlin, Sagolla, Meredith, Doerr, Jonas, Bolon, Brad, Ziai, James, Sun, Kai-Hui, Warming, Soren, Roose-Girma, Merone, Zhang, Na, Tam, Lucinda, Newman, Robert J, Chaudhuri, Subhra, Antony, Aju, Goldstein, Leonard D, Durinck, Steffen, Jaiswal, Bijay S, Lafkas, Daniel, Modrusan, Zora, Seshagiri, Somasekar

“…ERBB3 is a pseudokinase domain-containing member of the ERBB family of receptor tyrosine kinases (RTKs). Following ligand binding, ERBB receptors homo- or…”
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Massively parallel single-cell B-cell receptor sequencing enables rapid discovery of diverse antigen-reactive antibodies by Goldstein, Leonard D, Chen, Ying-Jiun J, Wu, Jia, Chaudhuri, Subhra, Hsiao, Yi-Chun, Schneider, Kellen, Hoi, Kam Hon, Lin, Zhonghua, Guerrero, Steve, Jaiswal, Bijay S, Stinson, Jeremy, Antony, Aju, Pahuja, Kanika Bajaj, Seshasayee, Dhaya, Modrusan, Zora, Hötzel, Isidro, Seshagiri, Somasekar

“…Obtaining full-length antibody heavy- and light-chain variable regions from individual B cells at scale remains a challenging problem. Here we use…”
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Draft Genome Sequences of Staphylococcus aureus AMRF1 (ST22) and AMRF2 (ST672), Ocular Methicillin-Resistant Isolates by Velusamy, Nithya, Prakash, Logambiga, Sivakumar, Neelamegam, Antony, Aju, Prajna, Lalitha, Mohankumar, Vidyarani, Devarajan, Bharanidharan

“…Sequence type 22 (ST22) and ST672 are the two major emerging clones of community-acquired methicillin-resistant Staphylococcus aureus in India. ST672 strains…”
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Construction of intein-mediated hGMCSF expression vector and its purification in Pichia pastoris by Babu, K. Srinivasa, Antony, Aju, Muthukumaran, T., Meenakshisundaram, S.

“…As a novel attempt for the intracellular recombinant protein over expression and easy purification from Pichia pastoris, the therapeutic cytokine human…”
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Draft Genome Sequence of a Highly Flagellated, Fast-Swimming Archaeon, Methanocaldococcus villosus Strain KIN24-T80 (DSM 22612) by Thennarasu, Sugumar, Polireddy, Dineshreddy, Antony, Aju, Yada, Madhava Rao, Algarawi, Sami, Sivakumar, Neelamegam

“…We report the draft genome sequence of a hyperthermophilic Methanocaldococcus villosus strain, KIN24-T80. The gene associated with its heavy flagellum…”
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Draft Genome Sequence of an Invasive Multidrug-Resistant Strain, Pseudomonas aeruginosa BK1, Isolated from a Keratitis Patient by Jeganathan, Lakshmi Priya, Prakash, Logambiga, Sivakumar, Neelamegam, Antony, Aju, Alqarawi, Sami, Prajna, Lalitha, Devarajan, Bharanidharan, Mohankumar, Vidyarani

“…Pseudomonas aeruginosa infections are difficult to treat due to the presence of a multitude of virulence factors and antibiotic resistance. Here, we report the…”
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Single step intein-mediated purification of hGMCSF expressed in salt-inducible E. coli by Srinivasa Babu, K, Muthukumaran, T, Antony, Aju, Prem Singh Samuel, S. D, Balamurali, M, Murugan, V, Meenakshisundaram, S

“…Human granulocyte-macrophage colony stimulating factor (hGMCSF) is an important therapeutic cytokine. As a novel attempt to purify hGMCSF protein, without the…”
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Restricted epitope specificity determined by variable region germline segment pairing in rodent antibody repertoires by Hsiao, Yi-Chun, Chen, Ying-Jiun J., Goldstein, Leonard D., Wu, Jia, Lin, Zhonghua, Schneider, Kellen, Chaudhuri, Subhra, Antony, Aju, Bajaj Pahuja, Kanika, Modrusan, Zora, Seshasayee, Dhaya, Seshagiri, Somasekar, Hötzel, Isidro

“…Antibodies from B-cell clonal lineages share sequence and structural properties as well as epitope specificity. Clonally unrelated antibodies can similarly…”
Get full text