Search Results - "Antonovaite, Nelda"
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Regional variations in stiffness in live mouse brain tissue determined by depth-controlled indentation mapping
Published in Scientific reports (21-08-2018)“…The mechanical properties of brain tissue play a pivotal role in neurodevelopment and neurological disorders. Yet, at present, there is no consensus on how the…”
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2
Viscoelastic properties of white and gray matter-derived microglia differentiate upon treatment with lipopolysaccharide but not upon treatment with myelin
Published in Journal of neuroinflammation (29-03-2021)“…The biomechanical properties of the brain have increasingly been shown to relate to brain pathology in neurological diseases, including multiple sclerosis…”
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In vivo characterization of chick embryo mesoderm by optical coherence tomography‐assisted microindentation
Published in The FASEB journal (01-09-2020)“…Embryos are growing organisms with highly heterogeneous properties in space and time. Understanding the mechanical properties is a crucial prerequisite for the…”
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Viscoelastic mapping of mouse brain tissue: Relation to structure and age
Published in Journal of the mechanical behavior of biomedical materials (01-01-2021)“…There is growing evidence that mechanical factors affect brain functioning. However, brain components responsible for regulating the physiological mechanical…”
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Micro-indentation and optical coherence tomography for the mechanical characterization of embryos: Experimental setup and measurements on chicken embryos
Published in Acta biomaterialia (01-10-2019)“…[Display omitted] The investigation of the mechanical properties of embryos is expected to provide valuable information on the phenomenology of morphogenesis…”
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Experimental and Data Analysis Workflow for Soft Matter Nanoindentation
Published in Journal of visualized experiments (18-01-2022)“…Nanoindentation refers to a class of experimental techniques where a micrometric force probe is used to quantify the local mechanical properties of soft…”
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Dynamic indentation reveals differential viscoelastic properties of white matter versus gray matter-derived astrocytes upon treatment with lipopolysaccharide
Published in Journal of the mechanical behavior of biomedical materials (01-09-2020)“…Astrocytes in white matter (WM) and gray matter (GM) brain regions have been reported to have different morphology and function. Previous single cell…”
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The effect of TGFβRI inhibition on extracellular matrix structure and stiffness in hypertrophic scar-specific fibroblast-derived matrix models
Published in Biochemical and biophysical research communications (25-06-2021)“…•A scar-specific FDM model was used to test the in vitro efficacy of ALK5 exon skipping.•ALK5 exon 2 skipping reduced parallel orientation of collagen in the…”
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Mechanical alterations of the hippocampus in the APP/PS1 Alzheimer’s disease mouse model
Published in Journal of the mechanical behavior of biomedical materials (01-10-2021)“…There is increasing evidence of altered tissue mechanics in neurodegeneration. However, due to difficulties in mechanical testing procedures and the complexity…”
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10
Structure-stiffness relation of live mouse brain tissue determined by depth-controlled indentation mapping
Published 06-02-2018“…The mechanical properties of brain tissue play a pivotal role in neurodevelopment and neurological disorders. Yet, at present, there is no consensus on how the…”
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