Search Results - "Antonio Villaverde"

Nanotechnology, bionanotechnology and microbial cell factories by Villaverde, Antonio

“…Nanotechnology is increasingly using both materials and nano-objects synthesized by living beings, most of them produced by microbial cells. Emerging…”
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Recombinant pharmaceuticals from microbial cells: a 2015 update by Sanchez-Garcia, Laura, Martín, Lucas, Mangues, Ramon, Ferrer-Miralles, Neus, Vázquez, Esther, Villaverde, Antonio

“…Diabetes, growth or clotting disorders are among the spectrum of human diseases related to protein absence or malfunction. Since these pathologies cannot be…”
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Biomedical applications of distally controlled magnetic nanoparticles by Corchero, José Luis, Villaverde, Antonio

“…Nano-sized magnetic particles are increasingly being used across a wide spectrum of biomedical fields. Upon functionalization to enable specific binding,…”
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Microbial factories for recombinant pharmaceuticals by Ferrer-Miralles, Neus, Domingo-Espín, Joan, Corchero, José Luis, Vázquez, Esther, Villaverde, Antonio

“…Most of the hosts used to produce the 151 recombinant pharmaceuticals so far approved for human use by the Food and Drug Administration (FDA) and/or by the…”
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Bacterial inclusion bodies are industrially exploitable amyloids by de Marco, Ario, Ferrer-Miralles, Neus, Garcia-Fruitós, Elena, Mitraki, Anna, Peternel, Spela, Rinas, Ursula, Trujillo-Roldán, Mauricio A, Valdez-Cruz, Norma A, Vázquez, Esther, Villaverde, Antonio

“…Understanding the structure, functionalities and biology of functional amyloids is an issue of emerging interest. Inclusion bodies, namely protein clusters…”
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Detoxifying Escherichia coli for endotoxin-free production of recombinant proteins by Mamat, Uwe, Wilke, Kathleen, Bramhill, David, Schromm, Andra Beate, Lindner, Buko, Kohl, Thomas Andreas, Corchero, José Luis, Villaverde, Antonio, Schaffer, Lana, Head, Steven Robert, Souvignier, Chad, Meredith, Timothy Charles, Woodard, Ronald Wesley

“…Lipopolysaccharide (LPS), also referred to as endotoxin, is the major constituent of the outer leaflet of the outer membrane of virtually all Gram-negative…”
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BBB-targeting, protein-based nanomedicines for drug and nucleic acid delivery to the CNS by Peluffo, Hugo, Unzueta, Ugutz, Negro-Demontel, María Luciana, Xu, Zhikun, Váquez, Esther, Ferrer-Miralles, Neus, Villaverde, Antonio

“…The increasing incidence of diseases affecting the central nervous system (CNS) demands the urgent development of efficient drugs. While many of these…”
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A CXCR4-targeted nanocarrier achieves highly selective tumor uptake in diffuse large B-cell lymphoma mouse models by Falgàs, Aïda, Pallarès, Victor, Unzueta, Ugutz, Céspedes, María Virtudes, Arroyo-Solera, Irene, Moreno, María José, Sierra, Jorge, Gallardo, Alberto, Mangues, María Antonia, Vázquez, Esther, Villaverde, Antonio, Mangues, Ramon, Casanova, Isolda

“…One-third of diffuse large B-cell lymphoma patients are refractory to initial treatment or relapse after rituximab plus cyclophosphamide, doxorubicin,…”
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Systems metabolic engineering, industrial biotechnology and microbial cell factories by Lee, Sang Yup, Mattanovich, Diethard, Villaverde, Antonio

“…Doc number: 156…”
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Annual acknowledgement of manuscript reviewers by Villaverde, Antonio

“…Doc number: 11 Contributing reviewers: The Editors of Microbial Cell Factories would like to thank all our Reviewers who have contributed to the journal in…”
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CXCR4-targeted nanotoxins induce GSDME-dependent pyroptosis in head and neck squamous cell carcinoma by Rioja-Blanco, Elisa, Arroyo-Solera, Irene, Álamo, Patricia, Casanova, Isolda, Gallardo, Alberto, Unzueta, Ugutz, Serna, Naroa, Sánchez-García, Laura, Quer, Miquel, Villaverde, Antonio, Vázquez, Esther, León, Xavier, Alba-Castellón, Lorena, Mangues, Ramon

“…Therapy resistance, which leads to the development of loco-regional relapses and distant metastases after treatment, constitutes one of the major problems that…”
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Photobiomodulation: Shining Light on COVID-19 by Fernandes, Adriana Barrinha, de Lima, Carlos José, Villaverde, Antônio G J Balbin, Pereira, Pamela Camila, Carvalho, Henrique Cunha, Zângaro, Renato Amaro

“…To evaluate the hypothesis that light could reduce the lethality of COVID-19. Most models for projections of the spread and lethality of COVID-19 take into…”
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Recombinant vaccines in 2022: a perspective from the cell factory by de Pinho Favaro, Marianna Teixeira, Atienza-Garriga, Jan, Martínez-Torró, Carlos, Parladé, Eloi, Vázquez, Esther, Corchero, José Luis, Ferrer-Miralles, Neus, Villaverde, Antonio

“…The last big outbreaks of Ebola fever in Africa, the thousands of avian influenza outbreaks across Europe, Asia, North America and Africa, the emergence of…”
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Fluorescence visualization efficacy for detecting oral lesions more prone to be dysplastic and potentially malignant disorders − a pilot study by Simonato, Luciana Estevam, Tomo, Saygo, Miyahara, Glauco Issamu, Navarro, Ricardo Scarparo, Villaverde, Antonio Jose Guillermo Balbin

“…Highlights • Present evidence indicating fluorescence visualization is a reliable method for early detection of neoplastic processes in oral mucosa. •…”
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Fluorescence visualization improves the detection of oral, potentially malignant, disorders in population screening by Simonato, Luciana Estevam, Tomo, Saygo, Scarparo Navarro, Ricardo, Balbin Villaverde, Antonio Guillermo Jose

“…•Fluorescence Visualization (FV) presented high diagnostic values when used by general practice dentists to detect OPMD and epithelial dysplasia.•FV improved…”
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Selective depletion of metastatic stem cells as therapy for human colorectal cancer by Céspedes, María Virtudes, Unzueta, Ugutz, Aviñó, Anna, Gallardo, Alberto, Álamo, Patricia, Sala, Rita, Sánchez‐Chardi, Alejandro, Casanova, Isolda, Mangues, María Antònia, Lopez‐Pousa, Antonio, Eritja, Ramón, Villaverde, Antonio, Vázquez, Esther, Mangues, Ramón

“…Selective elimination of metastatic stem cells (MetSCs) promises to block metastatic dissemination. Colorectal cancer (CRC) cells overexpressing CXCR4 display…”
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The conformational quality of insoluble recombinant proteins is enhanced at low growth temperatures by Vera, Andrea, González-Montalbán, Nuria, Arís, Anna, Villaverde, Antonio

“…Protein aggregation is a major bottleneck during the bacterial production of recombinant proteins. In general, the induction of gene expression at sub‐optimal…”
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GSDMD-dependent pyroptotic induction by a multivalent CXCR4-targeted nanotoxin blocks colorectal cancer metastases by Sala, Rita, Rioja-Blanco, Elisa, Serna, Naroa, Sánchez-García, Laura, Álamo, Patricia, Alba-Castellón, Lorena, Casanova, Isolda, López-Pousa, Antonio, Unzueta, Ugutz, Céspedes, María Virtudes, Vázquez, Esther, Villaverde, Antonio, Mangues, Ramon

“…Colorectal cancer (CRC) remains the third cause of cancer-related mortality in Western countries, metastases are the main cause of death. CRC treatment remains…”
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Protein folding and conformational stress in microbial cells producing recombinant proteins: a host comparative overview by Gasser, Brigitte, Saloheimo, Markku, Rinas, Ursula, Dragosits, Martin, Rodríguez-Carmona, Escarlata, Baumann, Kristin, Giuliani, Maria, Parrilli, Ermenegilda, Branduardi, Paola, Lang, Christine, Porro, Danilo, Ferrer, Pau, Tutino, Maria Luisa, Mattanovich, Diethard, Villaverde, Antonio

“…Different species of microorganisms including yeasts, filamentous fungi and bacteria have been used in the past 25 years for the controlled production of…”
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Lymphocyte infiltration and antitumoral effect promoted by cytotoxic inflammatory proteins formulated as self-assembling, protein-only nanoparticles by Martínez-Torró, Carlos, Alba-Castellón, Lorena, Carrasco-Díaz, Luis Miguel, Serna, Naroa, Imedio, Laura, Gallardo, Alberto, Casanova, Isolda, Unzueta, Ugutz, Vázquez, Esther, Mangues, Ramón, Villaverde, Antonio

“…Two human proteins involved in the inflammatory cell death, namely Gasdermin D (GSDMD) and the Mixed Lineage Kinase Domain-Like (MLKL) protein have been…”
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