Search Results - "Antonio Ferraz Coelho, Eduardo"
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Mapping B-cell epitopes for the peroxidoxin of Leishmania (Viannia) braziliensis and its potential for the clinical diagnosis of tegumentary and visceral leishmaniasis
Published in PloS one (12-06-2014)“…The search toward the establishment of novel serological tests for the diagnosis of leishmaniasis and proper differential diagnosis may represent one…”
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2
Evaluation of a hypothetical protein for serodiagnosis and as a potential marker for post-treatment serological evaluation of tegumentary leishmaniasis patients
Published in Parasitology research (1987) (01-04-2017)“…The serodiagnosis for tegumentary leishmaniasis (TL) presents problems related to the sensitivity and/or specificity of the tests. In the present study, an…”
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3
Synthesis and biological activity of novel 4-aminoquinoline/1,2,3-triazole hybrids against Leishmania amazonensis
Published in Biomedicine & pharmacotherapy (01-09-2021)“…Quinoline and 1,2,3-triazoles are well-known nitrogen-based heterocycles presenting diverse pharmacological properties, although their antileishmanial activity…”
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4
New antigens for the serological diagnosis of human visceral leishmaniasis identified by immunogenomic screening
Published in PloS one (20-12-2018)“…Visceral leishmaniasis (VL) still represents a serious public health problem in Brazil due to the inefficiency of the control measures currently employed, that…”
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Development of a chimeric protein based on a proteomic approach for the serological diagnosis of human tegumentary leishmaniasis
Published in Applied microbiology and biotechnology (01-09-2021)“…Leishmania braziliensis is responsible for most cases of human tegumentary leishmaniasis (HTL) and has caused a wide range of clinical manifestations,…”
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A Review on the use of Synthetic and Recombinant Antigens for the Immunodiagnosis of Tegumentary Leishmaniasis
Published in Current medicinal chemistry (01-01-2024)“…Improving the diagnostic technology used to detect tegumentary leishmaniasis (TL) is essential in view of it being a widespread, often neglected tropical…”
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Molecular Methods for Diagnosis of Monkeypox: A Mini-review
Published in Current molecular medicine (01-01-2024)“…Monkeypox is a global public health issue caused by the monkeypox virus (MPXV). As of October 28, 2022, a total of 77,115 laboratoryconfirmed cases and 3,610…”
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Recombinant proteins as promising antigens applied to the immunodiagnosis of Chagas disease: a scoping review
Published in Frontiers in microbiology (30-07-2024)“…Chagas disease (CD), caused by the protozoan , is an important public health problem, occurring mainly in Latin America. The disease has a major social and…”
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Targeting Leishmania infantum Mannosyl-oligosaccharide glucosidase with natural products: potential pH-dependent inhibition explored through computer-aided drug design
Published in Frontiers in pharmacology (30-05-2024)“…Visceral Leishmaniasis (VL) is a serious public health issue, documented in more than ninety countries, where an estimated 500,000 new cases emerge each year…”
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Parasitological and immunological evaluation of a quinoline derivative salt incorporated into a polymeric micelle formulation against Leishmania infantum infection
Published in Parasitology research (1987) (01-07-2022)“…Leishmaniasis is a parasitic disease caused by Leishmania protozoa, which presents a large spectrum of clinical manifestations. In the present study, a…”
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Recent updates and perspectives on approaches for the development of vaccines against visceral leishmaniasis
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-07-2016)“…Visceral leishmaniasis (VL) is one of the most important tropical diseases worldwide. Although chemotherapy has been widely used to treat this disease,…”
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12
Protective immunity against challenge with Leishmania ( Leishmania ) chagasi in beagle dogs vaccinated with recombinant A2 protein
Published in Vaccine (29-10-2008)“…Abstract In this study, we investigated in dogs the immunogenicity and protective immunity against Leishmania ( Leishmania ) chagasi infection induced by…”
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A Mini-review on Potentials Proteins/Peptides Applied for Serodiagnosis of Human Monkeypox Infection and Future Trends
Published in Protein and peptide letters (01-01-2023)“…Monkeypox is a zoonosis that re-emerged in 2022, generating cases in non-endemic countries for the disease and creating a public health issue. The rapid…”
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14
Accuracy of Diagnostic Tests for the Detection of Chagas Disease: A Systematic Review and Meta-Analysis
Published in Diagnostics (Basel) (01-11-2022)“…The present systematic review and meta-analysis about the accuracy of diagnostic tests aim to describe the findings of literature over the last thirty years…”
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15
Treatment of murine visceral leishmaniasis using an 8-hydroxyquinoline-containing polymeric micelle system
Published in Parasitology international (01-12-2016)“…Abstract New therapeutics are urgently needed to treat visceral leishmaniasis (VL). Due to the fact that drug discovery is a long and expensive process, the…”
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Synthesis of 1,2,3-Triazole-Containing Methoxylated Cinnamides and Their Antileishmanial Activity against the Leishmania braziliensis Species
Published in Pharmaceuticals (Basel, Switzerland) (07-08-2023)“…Leishmaniasis is a group of infectious diseases caused by protozoan parasites that belong to the genus Leishmania. Currently, there is no human vaccine, and…”
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Mimotope-based vaccines of Leishmania infantum antigens and their protective efficacy against visceral leishmaniasis
Published in PloS one (15-10-2014)“…The development of cost-effective prophylactic strategies to prevent leishmaniasis has become a high-priority. The present study has used the phage display…”
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Antigenicity, Immunogenicity and Protective Efficacy of Three Proteins Expressed in the Promastigote and Amastigote Stages of Leishmania infantum against Visceral Leishmaniasis
Published in PloS one (14-09-2015)“…In the present study, two Leishmania infantum hypothetical proteins present in the amastigote stage, LiHyp1 and LiHyp6, were combined with a promastigote…”
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A Systematic Review and Meta-Analysis Comparing the Diagnostic Accuracy Tests of COVID-19
Published in Diagnostics (Basel) (26-04-2023)“…In this paper, we present a systematic review and meta-analysis that aims to evaluate the reliability of coronavirus disease diagnostic tests in 2019…”
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20
A vaccine composed of a hypothetical protein and the eukaryotic initiation factor 5a from Leishmania braziliensis cross-protection against Leishmania amazonensis infection
Published in Immunobiology (1979) (01-02-2017)“…Graphical abstract…”
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