Search Results - "Antonio De la Vieja"

Vitamin D induces SIRT1 activation through K610 deacetylation in colon cancer by García-Martínez, José Manuel, Chocarro-Calvo, Ana, Martínez-Useros, Javier, Fernández-Aceñero, María Jesús, Fiuza, M Carmen, Cáceres-Rentero, José, De la Vieja, Antonio, Barbáchano, Antonio, Muñoz, Alberto, Larriba, María Jesús, García-Jiménez, Custodia

“…Posttranslational modifications of epigenetic modifiers provide a flexible and timely mechanism for rapid adaptations to the dynamic environment of cancer…”
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Molecular Analysis of the Sodium/Iodide Symporter: Impact on Thyroid and Extrathyroid Pathophysiology by De la Vieja, Antonio, Dohan, Orsolya, Levy, Orlie, Carrasco, Nancy

“…Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York De la Vieja, Antonio, Orsolya Dohan, Orlie Levy, and Nancy Carrasco…”
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Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer by Gutiérrez-Salmerón, María, García-Martínez, José Manuel, Martínez-Useros, Javier, Fernández-Aceñero, María Jesús, Viollet, Benoit, Olivier, Severine, Chauhan, Jagat, Lucena, Silvia R, De la Vieja, Antonio, Goding, Colin R, Chocarro-Calvo, Ana, García-Jiménez, Custodia

“…Coordination of gene expression with nutrient availability supports proliferation and homeostasis and is shaped by protein acetylation. Yet how…”
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The Sodium/Iodide Symporter (NIS): Characterization, Regulation, and Medical Significance by Dohán, Orsolya, De la Vieja, Antonio, Paroder, Viktoriya, Riedel, Claudia, Artani, Mona, Reed, Mia, Ginter, Christopher S, Carrasco, Nancy

“…The Na+/I− symporter (NIS) is an integral plasma membrane glycoprotein that mediates active I− transport into the thyroid follicular cells, the first step in…”
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Mesenchymal Stem Cells Delivery in Individuals with Different Pathologies: Multimodal Tracking, Safety and Future Applications by Belmar-López, Carolina, Vassaux, Georges, Medel-Martinez, Ana, Burnet, Jerome, Quintanilla, Miguel, Ramón Y Cajal, Santiago, Hernandez-Losa, Javier, De la Vieja, Antonio, Martin-Duque, Pilar

“…Due to their ease of isolation and their properties, mesenchymal stem cells (MSCs) have been widely investigated. MSCs have been proved capable of migration…”
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Regulation of Thyroid Oxidative State by Thioredoxin Reductase Has a Crucial Role in Thyroid Responses to Iodide Excess by Leoni, Suzana G, Kimura, Edna T, Santisteban, Pilar, De la Vieja, Antonio

“…The phenomenon that supraphysiological doses of iodide (I−) temporarily inhibit thyroid hormone synthesis is known as thyroid iodide autoregulation. Recovery…”
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Validation of dynamic risk stratification and impact of BRAF in risk assessment of thyroid cancer, a nation-wide multicenter study by Pérez-Fernández, Laura, Sastre, Julia, Zafón, Carles, Oleaga, Amelia, Castelblanco, Esmeralda, Capel, Ismael, Galofré, Juan C, Guadalix-Iglesias, Sonsoles, De la Vieja, Antonio, Riesco-Eizaguirre, Garcilaso

“…The dynamic risk stratification (DRS) is a relatively new system in thyroid cancer that considers the response to primary treatment to improve the initial risk…”
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Isolation and Characterization of Milk Exosomes for Use in Advanced Therapies by Medel-Martinez, Ana, Redrado-Osta, Ana, Crespo-Barreda, Alejandra, Sancho-Albero, Maria, Sánchez, Lourdes, Sebastián, Víctor, Pardo, María, de la Vieja, Antonio, Martín-Duque, Pilar

“…Exosomes are cell-derived extracellular vesicles (EVs) with diameters between 30 and 120 nm. In recent years, several studies have evaluated the therapeutic…”
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NIS Mediates Iodide Uptake in the Female Reproductive Tract and Is a Poor Prognostic Factor in Ovarian Cancer by Riesco-Eizaguirre, Garcilaso, Leoni, Suzana Garcia, Mendiola, Marta, Estevez-Cebrero, Maria Angeles, Gallego, Marta Ines, Redondo, Andrés, Hardisson, David, Santisteban, Pilar, De la Vieja, Antonio

“…Context: The sodium iodide symporter (NIS) mediates active transport of iodide into the thyroid and the lactating mammary glands and is highly expressed in…”
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New approach methods to improve human health risk assessment of thyroid hormone system disruption-a PARC project by Ramhøj, Louise, Axelstad, Marta, Baert, Yoni, Cañas-Portilla, Ana I, Chalmel, Frédéric, Dahmen, Lars, De La Vieja, Antonio, Evrard, Bertrand, Haigis, Ann-Cathrin, Hamers, Timo, Heikamp, Kim, Holbech, Henrik, Iglesias-Hernandez, Patricia, Knapen, Dries, Marchandise, Lorna, Morthorst, Jane E, Nikolov, Nikolai Georgiev, Nissen, Ana C V E, Oelgeschlaeger, Michael, Renko, Kostja, Rogiers, Vera, Schüürmann, Gerrit, Stinckens, Evelyn, Stub, Mette H, Torres-Ruiz, Monica, Van Duursen, Majorie, Vanhaecke, Tamara, Vergauwen, Lucia, Wedebye, Eva Bay, Svingen, Terje

“…Current test strategies to identify thyroid hormone (TH) system disruptors are inadequate for conducting robust chemical risk assessment required for…”
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Amino Acid Residues in Transmembrane Segment IX of the Na+/I– Symporter Play a Role in Its Na+ Dependence and Are Critical for Transport Activity by De la Vieja, Antonio, Reed, Mia D., Ginter, Christopher S., Carrasco, Nancy

“…The Na+/I– symporter (NIS) is a key plasma membrane glycoprotein that mediates Na+-dependent active I– transport in the thyroid, lactating breast, and other…”
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Role of iodide metabolism in physiology and cancer by De la Vieja, Antonio, Santisteban, Pilar

“…Iodide (I−) metabolism is crucial for the synthesis of thyroid hormones (THs) in the thyroid and the subsequent action of these hormones in the organism. I− is…”
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The complex regulation of NIS expression and activity in thyroid and extrathyroidal tissues by Riesco-Eizaguirre, Garcilaso, Santisteban, Pilar, De la Vieja, Antonio

“…The sodium/iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates active iodide transport into the thyroid gland and into several…”
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Radio-Iodide Treatment: From Molecular Aspects to the Clinical View by De la Vieja, Antonio, Riesco-Eizaguirre, Garcilaso

“…Thyroid radio-iodide therapy (RAI) is one of the oldest known and used targeted therapies. In thyroid cancer, it has been used for more than eight decades and…”
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Journey of the iodide transporter NIS: from its molecular identification to its clinical role in cancer by Riedel, Claudia, Dohán, Orsolya, De la Vieja, Antonio, Ginter, Christopher S, Carrasco, Nancy

“…The Na +/I − symporter (NIS) is an intrinsic plasma membrane protein that mediates the active transport of I − in the thyroid, lactating mammary gland, stomach…”
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Toxicity of nanoplastics for zebrafish embryos, what we know and where to go next by Torres-Ruiz, Monica, De la Vieja, Antonio, de Alba Gonzalez, Mercedes, Esteban Lopez, Marta, Castaño Calvo, Argelia, Cañas Portilla, Ana Isabel

“…Nanoplastics (NP) are an emerging threat to human health and there is a need to understand their toxicity. Zebrafish (ZF) is extensively used as a toxicology…”
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The BRAFV600E oncogene induces transforming growth factor beta secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer by Riesco-Eizaguirre, Garcilaso, Rodríguez, Irene, De la Vieja, Antonio, Costamagna, Eugenia, Carrasco, Nancy, Nistal, Manuel, Santisteban, Pilar

“…The activating mutation BRAF(V600E) is a frequent genetic event in papillary thyroid carcinomas (PTC) that predicts a poor prognosis, leading to loss of…”
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From obesity to diabetes and cancer: epidemiological links and role of therapies by García-Jiménez, Custodia, Gutiérrez-Salmerón, María, Chocarro-Calvo, Ana, García-Martinez, Jose Manuel, Castaño, Angel, De la Vieja, Antonio

“…Increasing evidence suggests a complex relationship between obesity, diabetes and cancer. Here we review the evidence for the association between obesity and…”
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Neurotoxicity and endocrine disruption caused by polystyrene nanoparticles in zebrafish embryo by Torres-Ruiz, Mónica, de Alba González, Mercedes, Morales, Mónica, Martin-Folgar, Raquel, González, Mª. Carmen, Cañas-Portilla, Ana I., De la Vieja, Antonio

“…Nanoplastics (NP) are present in aquatic and terrestrial ecosystems. Humans can be exposed to them through contaminated water, food, air, or personal care…”
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