Search Results - "Antonini, I"

An unusual complication of gastric banding: recurrent small bowel obstruction caused by the connecting tube by Zappa, M A, Lattuada, E, Mozzi, E, Francese, M, Antonini, I, Radaelli, S, Roviaro, G

“…Laparoscopic adjustable gastric banding (LAGB) is a widely performed surgical procedure for morbid obesity. The application of this mini-invasive approach has…”
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Synthesis, Antitumor Cytotoxicity, and DNA-Binding of Novel N-5,2-Di(ω-aminoalkyl)-2,6-dihydropyrazolo[3,4,5-kl]acridine-5-carboxamides by Antonini, Ippolito, Polucci, Paolo, Magnano, Amelia, Martelli, Sante

“…A series of DNA-binding potential antitumor agents bearing a cationic carboxamide side chain attached in position peri to an electron-withdrawing atom,…”
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N4-(ω-Aminoalkyl)-1-[(ω-aminoalkyl)amino]-4-acridinecarboxamides:  Novel, Potent, Cytotoxic, and DNA-Binding Agents by Antonini, Ippolito, Polucci, Paolo, Kelland, Lloyd R, Spinelli, Silvano, Pescalli, Nicoletta, Martelli, Sante

“…A series of DNA-binding potential antitumor agents, (ω-aminoalkyl)-4-acridinecarboxamides, has been prepared either by reduction of the corresponding…”
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DNA-binding antitumor agents: from pyrimido[5,6,1-de]acridines to other intriguing classes of acridine derivatives by Antonini, Ippolito

“…In the field of antitumor DNA-binding agents, the class of acridine derivatives play an important role either as number of compounds or as importance of their…”
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Rational Design, Synthesis, and Biological Evaluation of Bis(pyrimido[5,6,1-de]acridines) and Bis(pyrazolo[3,4,5-kl]acridine-5-carboxamides) as New Anticancer Agents by Antonini, Ippolito, Polucci, Paolo, Magnano, Amelia, Sparapani, Silvia, Martelli, Sante

“…The good results obtained with pyrimido[5,6,1-de]acridines 7 and with pyrazolo[3,4,5-kl]acridinecarboxamides 8 prompted us to the synthesis of two new series…”
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Synthesis and Biological Evaluation of New Asymmetrical Bisintercalators as Potential Antitumor Drugs by Antonini, Ippolito, Santoni, Giorgio, Lucciarini, Roberta, Amantini, Consuelo, Sparapani, Silvia, Magnano, Amelia

“…The good results obtained in the past decade with various types of potential bisintercalating agents, e.g., LU 79553, DMP 840, BisBFI, MCI3335, WMC-26, BisAC,…”
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Study of cancer of the mouth by ANTONINI, I

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The three problems of dental caries by ANTONINI, I

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Useful effects of efficient mastication by ANTONINI, I

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Halitosis by ANTONINI, I

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New concepts on the etiology of dental caries by ANTONINI, I

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Synthesis of 9,10-anthraquinone monoalkylaminoalkylhydrazones as potential antitumor drugs by Antonini, I, Polucci, P, Cola, D, Palmieri, G, Martelli, S, Bontemps-Gracz, M

“…In the constant search for new compounds endowed with antitumor activity we have synthesized a series of anthraquinone hydrazones, which can bee seen either as…”
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Synthesis and biological evaluation of mono- and bis-[(alkylamino)alkylamino] substituted thienopyridopyridazines, a new class of potential antitumor agents by Antonini, I, Cola, D, Polucci, P, Palmieri, G F, Martelli, S, Jenkins, T C

“…A new class of potential antitumor agents, provided with thieno[2',3':5,6]pyrido[2,3-d]pyridazin-9(4H)-one nucleus as chromophore, was synthesized. Thus, the…”
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2,3-Dihydro-1H,7H-pyrimido[5,6,1-d e]acridine-1,3,7-trione Derivatives, a Class of Cytotoxic Agents Active on Multidrug-Resistant Cell Lines:  Synthesis, Biological Evaluation, and Structure−Activity Relationships by Antonini, Ippolito, Polucci, Paolo, Kelland, Lloyd R, Menta, Ernesto, Pescalli, Nicoletta, Martelli, Sante

“…A series of DNA-intercalating potential antitumor agents, (amino)alkyl-substituted 2,3-dihydro-1H,7H-pyrimido[5,6,1-de]acridine-1,3,7-triones, has been…”
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Pyrimidoacridine derivatives as potential antitumor agents by Antonini, I, Cola, D, Martelli, S, Cholody, W M, Konopa, J

“…A series of some N-alkylaminoalkyl derivatives of pyrimido[5,6,1-d,e]acridine-1,3,7-trione (3) was synthesized as new potential antitumor drugs, starting from…”
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Synthesis of 7-oxo-7H-benzo[e]perimidine-4-carboxamides as potential antitumor drugs by Antonini, I, Polucci, P, Cola, D, Filippo Palmieri, G, Martelli, S

“…A series of 7-oxo-7H-benzo[e]perimidine-4-carboxamides (4a-f) was synthetized from the corresponding acid (3) and the suitable amines by the "mixed anhydride"…”
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The role of structural factors in the kinetics of cellular uptake of pyrazoloacridines and pyrazolopyrimidoacridinesImplications for overcoming multidrug resistance towards leukaemia K562/DOX cells by TARASIUK, J, MAJEWSKA, E, SEKSEK, O, ROGACKA, D, ANTONINI, I, GARNIERSUILLEROT, A, BOROWSKI, E

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New example of intramolecular 1,5-hydrogen transfer during diazotization reactions by Antonini, I, Franchetti, P, Grifantini, M, Martelli, S

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1-[(ω-aminoalkyl)amino]-4-[n-(ω-aminoalkyl)carbamoyl]-9-oxo-9,10-dihydroacridines as intercalating cytotoxic agents : Synthesis, DNA binding, and biological evaluation by ANTONINI, I, POLUCCI, P, JENKINS, T. C, KELLAND, L. R, MENTA, E, PESCALLI, N, STEFANSKA, B, MAZERSKI, J, MARTELLI, S

“…A series of DNA-intercalating potential antitumor agents, 1-[(omega-aminoalkyl)amino]-4-[N-(omega-aminoalkyl)carbamoyl]-9-oxo-9, 10-dihydroacridines, has been…”
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The role of side chains in the interaction of new antitumor pyrimidoacridinetriones with DNA: molecular dynamics simulations by Mazerski, J, Antonini, I, Martelli, S

“…Pyrimidoacridinetriones (PATs) are a new group of highly active antitumor compounds. It seems reasonable to assume that, like for some other acridine…”
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