Search Results - "Antonijoan, Rosa Maria"
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Intrinsically regulated learning is modulated by synaptic dopamine signaling
Published in eLife (30-08-2018)“…We recently provided evidence that an intrinsic reward-related signal-triggered by successful learning in absence of -modulated the entrance of new information…”
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2
Moderate Beer Intake and Cardiovascular Health in Overweight Individuals
Published in Nutrients (05-09-2018)“…Consistent epidemiological evidence indicates that low-to-moderate alcohol consumption is inversely associated with cardiovascular event presentation, while…”
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A validated clinical-genetic score for assessing the risk of thrombosis in patients with COVID-19 receiving thromboprophylaxis
Published in Haematologica (Roma) (01-09-2022)Get full text
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4
Apathy in Parkinson's disease: neurophysiological evidence of impaired incentive processing
Published in The Journal of neuroscience (23-04-2014)“…Apathy is one of the most common and debilitating nonmotor manifestations of Parkinson's disease (PD) and is characterized by diminished motivation, decreased…”
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Impact of pre-admission antithrombotic therapy on disease severity and mortality in patients hospitalized for COVID-19
Published in Journal of thrombosis and thrombolysis (01-01-2022)“…Anticoagulant therapy is a cornerstone treatment for coronavirus disease 2019 (COVID-19) due to the high rates of thromboembolic complications associated with…”
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6
Monitoring sleep depth: analysis of bispectral index (BIS) based on polysomnographic recordings and sleep deprivation
Published in Journal of clinical monitoring and computing (01-02-2017)“…The assessment and management of sleep are increasingly recommended in the clinical practice. Polysomnography (PSG) is considered the gold standard test to…”
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Pharmacodynamics assessment of Bemiparin after multiple prophylactic and single therapeutic doses in adult and elderly healthy volunteers and in subjects with varying degrees of renal impairment
Published in Thrombosis research (01-06-2014)“…Abstract Introduction Aging and renal impairment may prolong the half-life and lead to accumulation of low molecular weight heparins. Correct dosing is…”
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Safety Assessment and Pharmacodynamics of a Novel Ultra Low Molecular Weight Heparin (RO-14) in Healthy Volunteers – A First-Time-In-Human Single Ascending Dose Study
Published in Thrombosis research (01-04-2011)“…Abstract Introduction RO-14 is a novel ultra low molecular heparin. The purpose of this study was to evaluate the safety and pharmacodynamic profile of RO-14…”
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Safety and pharmacokinetic profile of fixed-dose ivermectin with an innovative 18mg tablet in healthy adult volunteers
Published in PLoS neglected tropical diseases (01-01-2018)“…ClinicalTrials.gov NCT03173742…”
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10
The role of opioid transmission in music‐induced pleasure
Published in Annals of the New York Academy of Sciences (01-02-2023)“…Studies conducted in rodents indicate a crucial role of the opioid circuit in mediating objective hedonic reactions to primary rewards. However, it remains…”
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Acute effects of ayahuasca on neuropsychological performance: differences in executive function between experienced and occasional users
Published in Psychopharmacology (01-12-2013)“…Background Ayahuasca, a South American psychotropic plant tea containing the psychedelic 5-HT 2A receptor agonist N , N -dimethyltryptamine, has been shown to…”
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First-in-Human Randomized Trial to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of the KDM1A Inhibitor Vafidemstat
Published in CNS drugs (01-03-2021)“…Background Vafidemstat, an inhibitor of the histone lysine-specific demethylase KDM1A, corrects cognition deficits and behavior alterations in rodent models…”
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The Kappa Opioid Receptor and the Sleep of Reason: Cortico-Subcortical Imbalance Following Salvinorin-A
Published in The international journal of neuropsychopharmacology (01-01-2022)“…Abstract Background The mechanisms through which kappa opioid receptor (KOR) agonists induce psychotomimetic effects are largely unknown, although the…”
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Salvinorin-A Induces Intense Dissociative Effects, Blocking External Sensory Perception and Modulating Interoception and Sense of Body Ownership in Humans
Published in The international journal of neuropsychopharmacology (01-11-2015)“…Background: Salvinorin-A is a terpene with agonist properties at the kappa-opioid receptor, the binding site of endogenous dynorphins. Salvinorin-A is found in…”
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Inhibition of alpha oscillations through serotonin-2A receptor activation underlies the visual effects of ayahuasca in humans
Published in European neuropsychopharmacology (01-07-2016)“…Ayahuasca is an Amazonian psychotropic plant tea typically obtained from two plants, Banisteriopsis caapi and Psychotria viridis. It contains the psychedelic…”
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Naltrexone but Not Ketanserin Antagonizes the Subjective, Cardiovascular, and Neuroendocrine Effects of Salvinorin-A in Humans
Published in The international journal of neuropsychopharmacology (01-07-2016)“…Background: Salvinorin-A is a terpene found in the leaves of the plant Salvia divinorum. When administered to humans, salvinorin-A induces an intense but…”
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Psychomotor and subjective effects of bilastine, hydroxyzine, and cetirizine, in combination with alcohol: a randomized, double-blind, crossover, and positive-controlled and placebo-controlled Phase I clinical trials
Published in Human psychopharmacology (01-03-2014)“…Objective The aim of this study was to compare the effects of concomitant administration of alcohol and bilastine versus alcohol alone on the central nervous…”
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Evaluation of a strategy to shorten the time to surgery in patients on antiplatelet therapy with a proximal femur fracture (AFFEcT Study): Study protocol for a multicenter randomized controlled clinical trial
Published in Medicine (Baltimore) (01-05-2019)“…Patients with femur fracture benefit from early surgery. Recent reports suggest that regional anesthesia may be superior to general anesthesia in these…”
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Impact of Chiral Bioanalytical Methods on the Bioequivalence of Ibuprofen Products Containing Ibuprofen Lysinate and Ibuprofen Base
Published in Chirality (New York, N.Y.) (01-05-2016)“…The purpose was to assess the impact of the use of a chiral bioanalytical method on the conclusions of a bioequivalence study that compared two ibuprofen…”
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Randomized, open-label, blinded-endpoint, crossover, single-dose study to compare the pharmacodynamics of torasemide-PR 10 mg, torasemide-IR 10 mg, and furosemide-IR 40 mg, in patients with chronic heart failure
Published in Drug design, development and therapy (01-01-2015)“…Diuretics are the primary treatment for the management of chronic heart failure (HF) symptoms and for the improvement of acute HF symptoms. The rate of…”
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