Radiotherapy and Breast Reconstruction: What Is the Ideal Timing? A Narrative Review

Women undergoing mastectomy choose to pursue breast reconstruction (BR) in order to reduce their body image distress.Adjuvant chest wall irradiation is associated with a negative cosmetic outcome. The aim of our review was to identify the optimal timing of BR relating to radiotherapy delivery. Using...

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Bibliographic Details
Published in:	Reviews on recent clinical trials Vol. 17; no. 2; p. 73
Main Authors:	Letsiou, Evanthia, Tsakatikas, Sergios, Vakis, George, Tsapakidis, Konstantinos, Charalampakis, Nikolaos, Diamantis, Alexandros, Poultsidi, Antigoni, Michelakis, Dimosthenis, de Bree, Eelco, Mauri, Davide, Tsoukalas, Nikolaos, Antoniades, Chrysostomos, Tolia, Maria
Format:	Journal Article
Language:	English
Published:	United Arab Emirates 01-01-2022
Subjects:	Breast Neoplasms - radiotherapy Breast Neoplasms - surgery Female Humans Mammaplasty - methods Mastectomy - methods Radiotherapy, Adjuvant Breast radiotherapy cancer review timing breast reconstruction
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Summary:	Women undergoing mastectomy choose to pursue breast reconstruction (BR) in order to reduce their body image distress.Adjuvant chest wall irradiation is associated with a negative cosmetic outcome. The aim of our review was to identify the optimal timing of BR relating to radiotherapy delivery. Using Cochrane Library, Embase, PubMed, Springer, Wanfang and CNKI, we performed a non-systematic review of articles published up to August 2021. There is no hard evidence in favor of immediate, delayed or 2-stage BR when post-mastectomy radiation is indicated. Immediate and 2-stage BR seem to be valid alternatives to delayed BR. Further research is essential in order to assess clinician and patient reported aesthetic outcomes and determine the optimal timing of BR in view of post-mastectomy radiotherapy, in breast cancer survivors.
ISSN:	1876-1038
DOI:	10.2174/1574887117666220314161609