Search Results - "Antonenko, Y."

Fifty Years of Research on Protonophores: Mitochondrial Uncoupling As a Basis for Therapeutic Action by Kotova, E A, Antonenko, Y N

“…Protonophores are compounds capable of electrogenic transport of protons across membranes. Protonophores have been intensively studied over the past 50 years…”
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Mitochondrial-targeted plastoquinone derivatives. Effect on senescence and acute age-related pathologies by Skulachev, M V, Antonenko, Y N, Anisimov, V N, Chernyak, B V, Cherepanov, D A, Chistyakov, V A, Egorov, M V, Kolosova, N G, Korshunova, G A, Lyamzaev, K G, Plotnikov, E Y, Roginsky, V A, Savchenko, A Y, Severina, I I, Severin, F F, Shkurat, T P, Tashlitsky, V N, Shidlovsky, K M, Vyssokikh, M Y, Zamyatnin, Jr, A A, Zorov, D B, Skulachev, V P

“…Plastoquinone, a very effective electron carrier and antioxidant of chloroplasts, was conjugated with decyltriphenylphosphonium to obtain a cation easily…”
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Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 1. Cationic plastoquinone derivatives: Synthesis and in vitro studies by Antonenko, Y. N, Avetisyan, A. V, Bakeeva, L. E, Chernyak, B. V, Chertkov, V. A, Domnina, L. V, Ivanova, O. Yu, Izyumov, D. S, Khailova, L. S, Klishin, S. S, Korshunova, G. A, Lyamzaev, K. G, Muntyan, M. S, Nepryakhina, O. K, Pashkovskaya, A. A, Pletjushkina, O. Yu, Pustovidko, A. V, Roginsky, V. A, Rokitskaya, T. I, Ruuge, E. K, Saprunova, V. B, Severina, I. I, Simonyan, R. A, Skulachev, I. V, Skulachev, M. V, Sumbatyan, N. V, Sviryaeva, I. V, Tashlitsky, V. N, Vassiliev, J. M, Vyssokikh, M. Yu, Yaguzhinsky, L. S, Zamyatnin, A. A. Jr, Skulachev, V. P

“…Synthesis of cationic plastoquinone derivatives (SkQs) containing positively charged phosphonium or rhodamine moieties connected to plastoquinone by decane or…”
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Deuterated polyunsaturated fatty acids inhibit photoirradiation-induced lipid peroxidation in lipid bilayers by Firsov, A.M., Franco, M.S.F., Chistyakov, D.V., Goriainov, S.V., Sergeeva, M.G., Kotova, E.A., Fomich, M.A., Bekish, A.V., Sharko, O.L., Shmanai, V.V., Itri, R., Baptista, M.S., Antonenko, Y.N., Shchepinov, M.S.

“…Lipid peroxidation (LPO) plays a key role in many age-related neurodegenerative conditions and other disorders. Light irradiation can initiate LPO through…”
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Linking 7-Nitrobenzo-2-oxa-1,3-diazole (NBD) to Triphenylphosphonium Yields Mitochondria-Targeted Protonophore and Antibacterial Agent by Iaubasarova, I. R., Khailova, L. S., Nazarov, P. A., Rokitskaya, T. I., Silachev, D. N., Danilina, T. I., Plotnikov, E. Y., Denisov, S. S., Kirsanov, R. S., Korshunova, G. A., Kotova, E. A., Zorov, D. B., Antonenko, Y. N.

“…Appending lipophilic cations to small molecules has been widely used to produce mitochondria-targeted compounds with specific activities. In this work, we…”
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Genetic Variability of the AcrAB-TolC Multidrug Efflux Pump Underlies SkQ1 Resistance in Gram-Negative Bacteria by Nazarov, P A, Kotova, E A, Skulachev, V P, Antonenko, Y N

“…SkQ1, a novel antibiotic targeting bacterial bioenergetics, is highly effective against both gram-positive and gram-negative bacteria. However, some…”
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Effect of cyanide on mitochondrial membrane depolarization induced by uncouplers by Khailova, L. S., Rokitskaya, T. I., Kotova, E. A., Antonenko, Y. N.

“…In this work, it was found that the ability of common uncouplers – carbonyl cyanide p -trifluoromethoxyphenyl-hydrazone (FCCP) and 2,4-dinitrophenol (DNP) – to…”
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Protonophoric and Photodynamic Effects of Fluorescein Decyl(triphenyl)phosphonium Ester on the Electrical Activity of Pond Snail Neurons by Popova, L. B., Kamysheva, A. L., Rokitskaya, T. I., Korshunova, G. A., Kirsanov, R. S., Kotova, E. A., Antonenko, Y. N.

“…Uncouplers of oxidative phosphorylation in mitochondria, which have been essential in elucidating the basic principles of cell bioenergetics, have recently…”
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Inhibition of oxidative hemolysis in erythrocytes by mitochondria-targeted antioxidants of SkQ series by Omarova, E. O., Antonenko, Y. N.

“…In the present work we studied the effect of antioxidants of the SkQ1 family (10-(6′-plastoquinonyl)decyltriphenylphosphonium) on the oxidative hemolysis of…”
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Mild uncoupling of respiration and phosphorylation as a mechanism providing nephro- and neuroprotective effects of penetrating cations of the SkQ family by Plotnikov, E. Y., Silachev, D. N., Jankauskas, S. S., Rokitskaya, T. I., Chupyrkina, A. A., Pevzner, I. B., Zorova, L. D., Isaev, N. K., Antonenko, Y. N., Skulachev, V. P., Zorov, D. B.

“…It is generally accepted that mitochondrial production of reactive oxygen species is nonlinearly related to the value of the mitochondrial membrane potential…”
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Novel pH-Sensitive Microbial Rhodopsin from Sphingomonas paucimobilis by Maliar, N., Okhrimenko, I. S., Petrovskaya, L. E., Alekseev, A. A., Kovalev, K. V., Soloviov, D. V., Popov, P. A., Rokitskaya, T. I., Antonenko, Y. N., Zabelskii, D. V., Dolgikh, D. A., Kirpichnikov, M. P., Gordeliy, V. I.

“…This work provides the first characteristics of the rhodopsin SpaR from Sphingomonas paucimobilis , aerobic bacteria associated with opportunistic infections…”
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Protective Effects of Mitochondria-Targeted Antioxidant SkQ in Aqueous and Lipid Membrane Environments by Antonenko, Y. N., Roginsky, V. A., Pashkovskaya, A. A., Rokitskaya, T. I., Kotova, E. A., Zaspa, A. A., Chernyak, B. V., Skulachev, V. P.

“…The antioxidant activity of mitochondria-targeted small molecules, SkQ1 and MitoQ (conjugates of a lipophilic decyltriphenylphosphonium cation with an…”
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Photodynamic damage to erythrocytes and liposomes sensitized by chlorophyll a derivatives by Belykh, D. V., Shevchenko, O. G., Firsov, A. M., Kotova, E. A., Khudyaeva, I. S., Plyusnina, S. N., Antonenko, Y. N.

“…A comparative study of photohemolysis of erythrocytes and photodamage to liposomes sensitized by the chlorophyll a derivatives is reported. The…”
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Erratum to: Novel pH-Sensitive Microbial Rhodopsin from Sphingomonas paucimobilis by Maliar, N, Okhrimenko, I S, Petrovskaya, L E, Alekseev, A A, Kovalev, K V, Soloviov, D V, Popov, P A, Rokitskaya, T I, Antonenko, Y N, Zabelskii, D V, Dolgikh, D A, Kirpichnikov, M P, Gordeliy, V I

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Erratum to: Novel pH-Sensitive Microbial Rhodopsin fromSphingomonas paucimobilis by Maliar, N., Okhrimenko, I. S., Petrovskaya, L. E., Alekseev, A. A., Kovalev, K. V., Soloviov, D. V., Popov, P. A., Rokitskaya, T. I., Antonenko, Y. N., Zabelskii, D. V., Dolgikh, D. A., Kirpichnikov, M. P., Gordeliy, V. I.

“…An Erratum to this paper has been published: https://doi.org/10.1134/S1607672921020198…”
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Peak intensity analysis as a method for estimation of fluorescent probe binding to artificial and natural nanoparticles: Tetramethylrhodamine uptake by isolated mitochondria by Perevoshchikova, I.V., Zorov, D.B., Antonenko, Y.N.

“…A modified version of fluorescence correlation spectroscopy (FCS) closely related to the photon counting histogram (PCH) method, which is used in the case of a…”
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Electrostatic binding of substituted metal phthalocyanines to enterobacterial cells: Its role in photodynamic inactivation by Strakhovskaya, M. G, Antonenko, Y. N, Pashkovskaya, A. A, Kotova, E. A, Kireev, V, Zhukhovitsky, V. G, Kuznetsova, N. A, Yuzhakova, O. A, Negrimovsky, V. M, Rubin, A. B

“…The effect of ionic substituents in zinc and aluminum phthalocyanine molecules and of membrane surface charge on the interaction of dyes with artificial…”
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An Abnormally High Closing Potential of the OMPF Porin Channel from Yersinia Ruckeri: The Role of Charged Residues and Intramolecular Bonds by Chistyulin, D K, Novikova, O D, Zelepuga, E A, Khomenko, V A, Likhatskaya, G N, Portnyagina, O Yu, Antonenko, Y N

“…Electrophysiological experiments on bilayer lipid membranes showed that the isolated outer membrane major porin of Yersinia ruckeri (YrOmpF) exhibits activity…”
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Photodynamic inactivation of gramicidin channels in bilayer lipid membranes: Protective efficacy of singlet oxygen quenchers depends on photosensitizer location by Rokitskaya, T. I., Firsov, A. M., Kotova, E. A., Antonenko, Y. N.

“…The impact of double bonds in fatty acyl tails of unsaturated lipids on the photodynamic inactivation of ion channels formed by the pentadecapeptide gramicidin…”
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Safranine O as a fluorescent probe for mitochondrial membrane potential studied on the single particle level and in suspension by Perevoshchikova, I. V, Sorochkina, A. I, Zorov, D. B, Antonenko, Y. N

“…The permeant cationic dye safranine O is often used to measure mitochondrial membrane potential due to the dependence of both its absorption and fluorescence…”
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