Search Results - "Anto, R J"

Molecular evidences for the chemosensitizing efficacy of liposomal curcumin in paclitaxel chemotherapy in mouse models of cervical cancer by Sreekanth, C N, Bava, S V, Sreekumar, E, Anto, R J

“…The microtubule-targeting antineoplastic agent, paclitaxel, is highly efficacious against a wide spectrum of human cancers. However, dose-limiting toxicity and…”
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Resveratrol chemosensitizes HER-2-overexpressing breast cancer cells to docetaxel chemoresistance by inhibiting docetaxel-mediated activation of HER-2–Akt axis by Vinod, B S, Nair, H H, Vijayakurup, V, Shabna, A, Shah, S, Krishna, A, Pillai, K S, Thankachan, S, Anto, R J

“…As breast cancer cells often develop chemoresistance, better therapeutic options are in search to circumvent it. Here we demonstrate that human epidermal…”
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Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl by Anto, Ruby John, Mukhopadhyay, Asok, Denning, Kate, Aggarwal, Bharat B.

“…Pharmacologically safe compounds that can inhibit the proliferation of tumor cells have potential as anticancer agents. Curcumin, a diferuloylmethane, is a…”
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Anticancer and antioxidant activity of synthetic chalcones and related compounds by Anto, Ruby John, Sukumaran, K., Kuttan, Girija, Rao, M.N.A., Subbaraju, V., Kuttan, Ramadasan

“…Nineteen synthetic chalcones and ten structurally related compounds were investigated for their cytotoxic, tumour reducing and antioxidant activities. Methyl…”
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FT-IR, FT-Raman and SERS spectra of anilinium sulfate by Anto, P. L., Anto, R. J., Varghese, H. T., Panicker, C. Y., Philip, D., Brolo, A. G.

“…The FT‐IR and FT‐Raman spectra of anilinium sulfate were recorded and analyzed. The surface‐enhanced Raman scattering (SERS) was recorded from a silver…”
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Cigarette smoke condensate activates nuclear transcription factor-κB through phosphorylation and degradation of IκBα: correlation with induction of cyclooxygenase-2 by Anto, Ruby John, Mukhopadhyay, Asok, Shishodia, Shishir, Gairola, C. Gary, Aggarwal, Bharat B.

“…Cigarette smoke (CS) contains several carcinogens known to initiate and promote tumorigenesis and metastasis. Because various genes that mediate carcinogenesis…”
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Inhibition of NF-κB Sensitizes A431 Cells to Epidermal Growth Factor-induced Apoptosis, whereas Its Activation by Ectopic Expression of RelA Confers Resistance by Anto, Ruby John, Venkatraman, Manickam, Karunagaran, Devarajan

“…Epidermal growth factor (EGF) is a well known mitogen, but it paradoxically induces apoptosis in cells that overexpress its receptor. We demonstrate for the…”
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Anti-tumour and free radical scavenging activity of synthetic curcuminoids by Anto, Ruby John, Kuttan, Girija, Babu, K.V.Dinesh, Rajasekharan, K.N., Kuttan, Ramadasan

“…Eight synthetic curcuminoids were investigated for their cytotoxic and tumoricidal activities as well as for their free radical scavenging activity. All the…”
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Cigarette smoke condensate activates nuclear transcription factor-kappaB through phosphorylation and degradation of IkappaBalpha: correlation with induction of cyclooxygenase-2 by Anto, R. J.

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Sensitization of Taxol-induced Apoptosis by Curcumin Involves Down-regulation of Nuclear Factor-κB and the Serine/Threonine Kinase Akt and Is Independent of Tubulin Polymerization by Bava, Smitha V., Puliappadamba, Vineshkumar T., Deepti, Ayswaria, Nair, Asha, Karunagaran, Devarajan, Anto, Ruby John

“…Taxol is the best anticancer agent that has ever been isolated from plants, but its major disadvantage is its dose-limiting toxicity. In this study, we report…”
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Allicin (from garlic) induces caspase-mediated apoptosis in cancer cells by Oommen, Suby, Anto, Ruby John, Srinivas, Gopal, Karunagaran, Devarajan

“…Garlic ( Allium sativum) has been used for centuries for treating various ailments, and its consumption is said to reduce cancer risk and its extracts and…”
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L-929 Cells Harboring Ectopically Expressed RelA Resist Curcumin-induced Apoptosis by Anto, Ruby John, Maliekal, Tessy T., Karunagaran, Devarajan

“…Curcumin (diferuloyl methane), the yellow pigment in turmeric (Curcuma longa), is a potent chemopreventive agent. Curcumin induces apoptosis of several, but…”
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Cross-linked acrylic hydrogel for the controlled delivery of hydrophobic drugs in cancer therapy by Deepa, G, Thulasidasan, Arun Kumar T, Anto, Ruby John, Pillai, J Jisha, Kumar, G S Vinod

“…To investigate cross-linked hydrogels prepared via inverse emulsion polymerization to entrap poorly aqueous soluble drugs. Polyethylene glycol cross-linked…”
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Emodin induces apoptosis of human cervical cancer cells through poly(ADP-ribose) polymerase cleavage and activation of caspase-9 by Srinivas, Gopal, Anto, Ruby John, Srinivas, Priya, Vidhyalakshmi, Subramanian, Senan, Vijayamma Priya, Karunagaran, Devarajan

“…Emodin (1,3,8-trihydroxy-6-methylanthraquinone) is an active herbal component traditionally used in China for treating various ailments. Emodin exerts…”
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Antimutagenic and anticarcinogenic activity of natural and synthetic curcuminoids by Anto, Ruby John, George, Josely, Babu, K.V. Dinesh, Rajasekharan, K.N., Kuttan, Ramadasan

“…Five synthetic curcuminoids and three natural curcuminoids were investigated for their antimutagenic and anti-promotional activity. The natural curcuminoids,…”
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Biological and chemical inhibitors of NF-κB sensitize SiHa cells to cisplatin-induced apoptosis by Venkatraman, Manickam, Anto, Ruby John, Nair, Asha, Varghese, Merina, Karunagaran, Devarajan

“…Cisplatin, a chemotherapeutic agent, is known to induce apoptosis of cancer cells. We examined the role of NF‐κB during cisplatin‐induced apoptosis in two…”
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Adiabatic intramolecular movements for water systems by Pedroza, Luana S, Silva, Anto Nio J R da

“…An effective treatment of the intramolecular degrees of freedom is presented for water, where these modes are decoupled from the intermolecular ones,…”
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Differential activation of Smads in HeLa and SiHa cells that differ in their response to transforming growth factor-beta by Maliekal, Tessy T, Anto, Ruby John, Karunagaran, Devarajan

“…We assessed the responsiveness of six human cervical cancer cell lines to transforming growth factor (TGF)-beta with p3TP-lux reporter assay and found that…”
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