Search Results - "Antioxidants & redox signaling"

The Role of Sirtuins in Antioxidant and Redox Signaling by Singh, Chandra K, Chhabra, Gagan, Ndiaye, Mary Ann, Garcia-Peterson, Liz Mariely, Mack, Nicholas J, Ahmad, Nihal

“…Antioxidant and redox signaling (ARS) events are regulated by critical molecules that modulate antioxidants, reactive oxygen species (ROS) or reactive nitrogen…”
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NAD(H) and NADP(H) Redox Couples and Cellular Energy Metabolism by Xiao, Wusheng, Wang, Rui-Sheng, Handy, Diane E, Loscalzo, Joseph

“…The nicotinamide adenine dinucleotide (NAD )/reduced NAD (NADH) and NADP /reduced NADP (NADPH) redox couples are essential for maintaining cellular redox…”
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A Review of Hydrogen Sulfide Synthesis, Metabolism, and Measurement: Is Modulation of Hydrogen Sulfide a Novel Therapeutic for Cancer? by Cao, Xu, Ding, Lei, Xie, Zhi-Zhong, Yang, Yong, Whiteman, Matthew, Moore, Philip K, Bian, Jin-Song

“…Hydrogen sulfide (H S) has been recognized as the third gaseous transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous studies…”
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The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus by Gerber, Philipp A, Rutter, Guy A

“…Metabolic syndrome is a frequent precursor of type 2 diabetes mellitus (T2D), a disease that currently affects ∼8% of the adult population worldwide…”
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Reactive oxygen species in inflammation and tissue injury by Mittal, Manish, Siddiqui, Mohammad Rizwan, Tran, Khiem, Reddy, Sekhar P, Malik, Asrar B

“…Abstract Reactive oxygen species (ROS) are key signaling molecules that play an important role in the progression of inflammatory disorders. An enhanced ROS…”
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Diabetes and Kidney Disease: Role of Oxidative Stress by Jha, Jay C, Banal, Claudine, Chow, Bryna S M, Cooper, Mark E, Jandeleit-Dahm, Karin

“…Intrarenal oxidative stress plays a critical role in the initiation and progression of diabetic kidney disease (DKD). Enhanced oxidative stress results from…”
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Clinical Relevance of Biomarkers of Oxidative Stress by Frijhoff, Jeroen, Winyard, Paul G, Zarkovic, Neven, Davies, Sean S, Stocker, Roland, Cheng, David, Knight, Annie R, Taylor, Emma Louise, Oettrich, Jeannette, Ruskovska, Tatjana, Gasparovic, Ana Cipak, Cuadrado, Antonio, Weber, Daniela, Poulsen, Henrik Enghusen, Grune, Tilman, Schmidt, Harald H H W, Ghezzi, Pietro

“…Oxidative stress is considered to be an important component of various diseases. A vast number of methods have been developed and used in virtually all…”
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Oxidative Stress and Endothelial Dysfunction in Sepsis and Acute Inflammation by Joffre, Jérémie, Hellman, Judith

“…Under homeostatic conditions, the endothelium dynamically regulates vascular barrier function, coagulation pathways, leukocyte adhesion, and vasomotor tone…”
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Oxidant Mechanisms in Renal Injury and Disease by Ratliff, Brian B, Abdulmahdi, Wasan, Pawar, Rahul, Wolin, Michael S

“…A common link between all forms of acute and chronic kidney injuries, regardless of species, is enhanced generation of reactive oxygen species (ROS) and…”
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An overview of autophagy: morphology, mechanism, and regulation by Parzych, Katherine R, Klionsky, Daniel J

“…Autophagy is a highly conserved eukaryotic cellular recycling process. Through the degradation of cytoplasmic organelles, proteins, and macromolecules, and the…”
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Redox regulation of NLRP3 inflammasomes: ROS as trigger or effector? by Abais, Justine M, Xia, Min, Zhang, Yang, Boini, Krishna M, Li, Pin-Lan

“…Inflammasomes are multiprotein complexes localized within the cytoplasm of the cell that are responsible for the maturation of proinflammatory cytokines such…”
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SIRT1 and SIRT6 Signaling Pathways in Cardiovascular Disease Protection by D'Onofrio, Nunzia, Servillo, Luigi, Balestrieri, Maria Luisa

“…Oxidative stress represents the common hallmark of pathological conditions associated with cardiovascular disease (CVD), including atherosclerosis, heart…”
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Endoplasmic reticulum stress and oxidative stress in cell fate decision and human disease by Cao, Stewart Siyan, Kaufman, Randal J

“…The endoplasmic reticulum (ER) is a specialized organelle for the folding and trafficking of proteins, which is highly sensitive to changes in intracellular…”
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Effect of Particulate Matter Air Pollution on Cardiovascular Oxidative Stress Pathways by Rao, Xiaoquan, Zhong, Jixin, Brook, Robert D, Rajagopalan, Sanjay

“…Particulate matter (PM) air pollution is a leading cause of global cardiovascular morbidity and mortality. Understanding the biological action of PM is of…”
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The Redox Code by Jones, Dean P, Sies, Helmut

“…The redox code is a set of principles that defines the positioning of the nicotinamide adenine dinucleotide (NAD, NADP) and thiol/disulfide and other redox…”
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Dietary (poly)phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases by Del Rio, Daniele, Rodriguez-Mateos, Ana, Spencer, Jeremy P E, Tognolini, Massimiliano, Borges, Gina, Crozier, Alan

“…Human intervention trials have provided evidence for protective effects of various (poly)phenol-rich foods against chronic disease, including cardiovascular…”
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The Reactive Species Interactome: Evolutionary Emergence, Biological Significance, and Opportunities for Redox Metabolomics and Personalized Medicine by Cortese-Krott, Miriam M, Koning, Anne, Kuhnle, Gunter G C, Nagy, Peter, Bianco, Christopher L, Pasch, Andreas, Wink, David A, Fukuto, Jon M, Jackson, Alan A, van Goor, Harry, Olson, Kenneth R, Feelisch, Martin

“…Oxidative stress is thought to account for aberrant redox homeostasis and contribute to aging and disease. However, more often than not, administration of…”
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Proline Metabolism in Cell Regulation and Cancer Biology: Recent Advances and Hypotheses by Phang, James M

“…It is increasingly clear that proline metabolism plays an important role in metabolic reprogramming, not only in cancer but also in related fields such as…”
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Evaluating Cell Metabolism Through Autofluorescence Imaging of NAD(P)H and FAD by Kolenc, Olivia I, Quinn, Kyle P

“…Optical imaging using the endogenous fluorescence of metabolic cofactors has enabled nondestructive examination of dynamic changes in cell and tissue function…”
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Oxidative Stress as a Critical Factor in Nonalcoholic Fatty Liver Disease Pathogenesis by Spahis, Schohraya, Delvin, Edgard, Borys, Jean-Michel, Levy, Emile

“…Nonalcoholic fatty liver disease (NAFLD), characterized by liver triacylglycerol build-up, has been growing in the global world in concert with the raised…”
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