Search Results - "Antimisiaris, Sophia G."

Exosomes and Exosome-Inspired Vesicles for Targeted Drug Delivery by Antimisiaris, Sophia G, Mourtas, Spyridon, Marazioti, Antonia

“…The similarities between exosomes and liposomes, together with the high organotropism of several types of exosomes, have recently prompted the development of…”
Get full text

Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs by Agrawal, Mukta, Saraf, Swarnlata, Saraf, Shailendra, Antimisiaris, Sophia G., Chougule, Mahavir Bhupal, Shoyele, Sunday A., Alexander, Amit

“…According to the Alzheimer Association Report (2017), Alzheimer's disease (AD) is the 6th primary cause of death in the USA, which affects nearly 5.5 million…”
Get full text

Synthesis of α,ω-bis-Mercaptoacyl Poly(alkyl oxide)s and Development of Thioether Cross-Linked Liposome Scaffolds for Sustained Release of Drugs by Mourtas, Spyridon, Kourmoulakis, Georgios, Kremezis, Stavros, Klepetsanis, Pavlos, Antimisiaris, Sophia G

“…With the aim to develop novel scaffolds for the sustained release of drugs, we initially developed an easy approach for the synthesis of α,ω-homobifunctional…”
Get full text

Synergistic effect of cold atmospheric pressure plasma and free or liposomal doxorubicin on melanoma cells by Pefani-Antimisiari, Konstantina, Athanasopoulos, Dimitrios K., Marazioti, Antonia, Sklias, Kyriakos, Rodi, Maria, de Lastic, Anne-Lise, Mouzaki, Athanasia, Svarnas, Panagiotis, Antimisiaris, Sophia G.

“…The aim of the present study was to investigate combined effects of cold atmospheric plasma (CAP) and the chemotherapeutic drug doxorubicin (DOX) on murine and…”
Get full text

Curcumin-conjugated nanoliposomes with high affinity for Aβ deposits: Possible applications to Alzheimer disease by Lazar, Adina N., PhD, Mourtas, Spyridon, PhD, Youssef, Ihsen, PhD, Parizot, Christophe, MS, Dauphin, Aurélien, PhD, Delatour, Benoît, PhD, Antimisiaris, Sophia G., PhD, Duyckaerts, Charles, MD, PhD

“…Abstract Accumulation of amyloid peptide (Aβ) in senile plaques is a hallmark lesion of Alzheimer disease (AD). The design of molecules able to target the…”
Get full text

pH-Responsive Hydrogel/Liposome Soft Nanocomposites For Tuning Drug Release by Popescu, Maria-Teodora, Mourtas, Spyridon, Pampalakis, Georgios, Antimisiaris, Sophia G, Tsitsilianis, Constantinos

“…A novel liposome/hydrogel soft nanocomposite was explored as a controlled drug delivery system. A P2VP-PAA-PnBMA biocompatible, pH-responsive triblock…”
Get full text

Mutant KRAS promotes malignant pleural effusion formation by Agalioti, Theodora, Giannou, Anastasios D., Krontira, Anthi C., Kanellakis, Nikolaos I., Kati, Danai, Vreka, Malamati, Pepe, Mario, Spella, Magda, Lilis, Ioannis, Zazara, Dimitra E., Nikolouli, Eirini, Spiropoulou, Nikolitsa, Papadakis, Andreas, Papadia, Konstantina, Voulgaridis, Apostolos, Harokopos, Vaggelis, Stamou, Panagiota, Meiners, Silke, Eickelberg, Oliver, Snyder, Linda A., Antimisiaris, Sophia G., Kardamakis, Dimitrios, Psallidas, Ioannis, Marazioti, Antonia, Stathopoulos, Georgios T.

“…Malignant pleural effusion (MPE) is the lethal consequence of various human cancers metastatic to the pleural cavity. However, the mechanisms responsible for…”
Get full text

Liposomes Coated with Novel Synthetic Bifunctional Chitosan Derivatives as Potential Carriers of Anticancer Drugs by Mazzotta, Elisabetta, Marazioti, Antonia, Mourtas, Spyridon, Muzzalupo, Rita, Antimisiaris, Sophia G

“…In this study, liposomes coated with novel multifunctional polymers were proposed as an innovative platform for tumor targeted drug delivery. Novel Folic…”
Get full text

Development and Comparative In Vitro and In Vivo Study of BNN27 Mucoadhesive Liposomes and Nanoemulsions for Nose-to-Brain Delivery by Kannavou, Maria, Karali, Kanelina, Katsila, Theodora, Siapi, Eleni, Marazioti, Antonia, Klepetsanis, Pavlos, Calogeropoulou, Theodora, Charalampopoulos, Ioannis, Antimisiaris, Sophia G

“…Intranasal administration offers an alternative and promising approach for direct nose-to-brain delivery. Herein, we developed two chitosan (CHT)-coated (and…”
Get full text

Daptomycin Liposomes Exhibit Enhanced Activity against Staphylococci Biofilms Compared to Free Drug by Gkartziou, Foteini, Plota, Maria, Kypraiou, Charikleia, Gauttam, Iti, Kolonitsiou, Fevronia, Klepetsanis, Pavlos, Spiliopoulou, Iris, Antimisiaris, Sophia G

“…The purpose of the present study was to investigate the anti-staphylococcal activity of liposomal daptomycin against four biofilm-producing and clinical…”
Get full text

Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide by Taylor, Mark, PhD, Moore, Susan, PhD, Mourtas, Spyridon, PhD, Niarakis, Anna, PhD, Re, Francesca, PhD, Zona, Cristiano, PhD, Ferla, Barbara La, PhD, Nicotra, Francesco, PhD, Masserini, Massimo, PhD, Antimisiaris, Sophia G., PhD, Gregori, Maria, PhD, Allsop, David, PhD

“…Abstract The effect of various types of nanoliposomes (associated with curcumin, phosphatidic acid, cardiolipin, or GM1 ganglioside) on the aggregation of the…”
Get full text

Preparation of Benzothiazolyl-Decorated Nanoliposomes by Mourtas, Spyridon, Christodoulou, Panayiota, Klepetsanis, Pavlos, Gatos, Dimitrios, Barlos, Kleomenis, Antimisiaris, Sophia G

“…Amyloid β (Aβ) species are considered as potential targets for the development of diagnostics/therapeutics towards Alzheimer's disease (AD). Nanoliposomes…”
Get full text

Moxifloxacin Liposomes: Effect of Liposome Preparation Method on Physicochemical Properties and Antimicrobial Activity against Staphylococcus epidermidis by Natsaridis, Evangelos, Gkartziou, Foteini, Mourtas, Spyridon, Stuart, Marc C A, Kolonitsiou, Fevronia, Klepetsanis, Pavlos, Spiliopoulou, Iris, Antimisiaris, Sophia G

“…The aim of this study was the development of optimal sustained-release moxifloxacin (MOX)-loaded liposomes as intraocular therapeutics of endophthalmitis. Two…”
Get full text

Nanobiosystems for Antimicrobial Drug-Resistant Infections by Gkartziou, Foteini, Giormezis, Nikolaos, Spiliopoulou, Iris, Antimisiaris, Sophia G

“…The worldwide increased bacterial resistance toward antimicrobial therapeutics has led investigators to search for new therapeutic options. Some of the options…”
Get full text

Preparation, Physicochemical Properties, and In Vitro Toxicity towards Cancer Cells of Novel Types of Arsonoliposomes by Zagana, Paraskevi, Mourtas, Spyridon, Basta, Anastasia, Antimisiaris, Sophia G

“…Arsonoliposomes (ARSL) are liposomes that incorporate arsonolipids (ARS) in their membranes. They have demonstrated significant toxicity towards cancer cells,…”
Get full text

Liposomal Entrapment or Chemical Modification of Relaxin2 for Prolongation of Its Stability and Biological Activity by Kogkos, George, Gkartziou, Foteini, Mourtas, Spyridon, Barlos, Kostas K, Klepetsanis, Pavlos, Barlos, Kleomenis, Antimisiaris, Sophia G

“…Relaxin (RLX) is a protein that is structurally similar to insulin and has interesting biological activities. As with all proteins, preservation of RLX’s…”
Get full text

In Vitro Anti-Biofilm Activity of Bacteriophage K (ATCC 19685-B1) and Daptomycin against Staphylococci by Plota, Maria, Sazakli, Eleni, Giormezis, Nikolaos, Gkartziou, Foteini, Kolonitsiou, Fevronia, Leotsinidis, Michalis, Antimisiaris, Sophia G, Spiliopoulou, Iris

“…The purpose of the present study was to investigate anti-staphylococcal activity of daptomycin and bacteriophage K, alone or in combination, against…”
Get full text

Medical Device Development for Children and Young People-Reviewing the Challenges and Opportunities by Dimitri, Paul, Pignataro, Valeria, Lupo, Mariangela, Bonifazi, Donato, Henke, Maria, Musazzi, Umberto M, Ernst, Floris, Minghetti, Paola, Redaelli, Davide F, Antimisiaris, Sophia G, Migliaccio, Giovanni, Bonifazi, Fedele, Marciani, Luca, Courtenay, Aaron J, Denora, Nunzio, Lopedota, Angela

“…Development of specific medical devices (MDs) is required to meet the healthcare needs of children and young people (CYP). In this context, MD development…”
Get full text

Synthesis of Novel Arsonolipids and Development of Novel Arsonoliposome Types by Mourtas, Spyridon, Papadia, Konstantina, Kordopati, Golfo G, Ioannou, Panayiotis V, Antimisiaris, Sophia G, Tsivgoulis, Gerasimos M

“…Arsonolipids represent a class of arsenic-containing compounds with interesting biological properties either as monomers or as nanostructure forming…”
Get full text

Magnetoliposomes with high USPIO entrapping efficiency, stability and magnetic properties by Skouras, Athanasios, MSc, Mourtas, Spyridon, PhD, Markoutsa, Eleni, MSc, De Goltstein, Marie-Christine, MSc, Wallon, Claire, MSc, Catoen, Sarah, PhD, Antimisiaris, Sophia G., PhD

“…Abstract The DRV technique (followed by extrusion) was used for construction of hydrophilic-USPIO encapsulating liposomes. Magnetoliposomes (ML) were…”
Get full text