Andrographis paniculata-mediated synthesis of silver nanoparticles: antimicrobial properties and computational studies

The present work reports a simple-economical procedure for the formation of silver nanoparticles by using controlled addition of concentration of cetyltrimethylammonium bromide (CTAB) as a capping agent, taking one-factor-at-a-time into consideration during the optimization process. Wet chemical met...

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Bibliographic Details
Published in:	SN applied sciences Vol. 2; no. 9; p. 1618
Main Authors:	Anantharaman, Shivakumar, Rego, Reena, Muthakka, Moksha, Anties, Tinto, Krishna, Honnur
Format:	Journal Article
Language:	English
Published:	Cham Springer International Publishing 01-09-2020 Springer Nature B.V
Subjects:	Andrographis paniculata Antimicrobial agents Antioxidants Applied and Technical Physics Cetyltrimethylammonium bromide Chemistry/Food Science Chemistry: Green Synthesis of Nanoparticles Computer applications Earth Sciences Engineering Environment Fourier transforms Fungicides Ketoconazole Materials Science Methods Morphology Nanomaterials Nanoparticles Nitric oxide Optimization Particle size Phenols Quantum confinement Reagents Research Article Silver Sodium Software Spectroscopy Streptomycin Surface chemistry Surfactants X ray powder diffraction X-ray diffraction Asia India Tauc plot Mie plot Disc diffusion assay Nano silver Green synthesis Antioxidant assay
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Summary:	The present work reports a simple-economical procedure for the formation of silver nanoparticles by using controlled addition of concentration of cetyltrimethylammonium bromide (CTAB) as a capping agent, taking one-factor-at-a-time into consideration during the optimization process. Wet chemical method for silver(I) reduction has been used to synthesize nanoparticles using Andrographis paniculata. During the reaction, antioxidant property of biosystem reduces silver(I) to metallic silver(0) and CTAB encapsulates preventing the agglomeration, acting as barrier for the growth of the particle. The synthesised nanoparticle was characterised by powder X-ray diffraction, Fourier-transform spectroscopy, UV–Vis spectroscopy and SEM. The results showed that the silver nanoparticles doped with CTAB and its high crystallinity can be obtained using simple solvent method. The size of the nanoparticle by XRD, UV–Vis and SEM were found to be 0.897 nm, 45 nm and 18 to 43 nm, respectively. Tauc’s plot of optical band gap suggested the movement of size towards quantum confinement for the synthesised nanoparticles was 2.25 eV. An antioxidant activity of A. paniculata and synthesized AgNps was studied by series of antioxidant assays. The nanoparticles were having antibacterial and antifungal activities when it was studied using Streptomycin and Ketoconazole as controls. Graphic abstract
ISSN:	2523-3963 2523-3971
DOI:	10.1007/s42452-020-03394-7