Search Results - "Anti-cancer agents in medicinal chemistry"

Reactive Oxygen Species (ROS): Key Components in Cancer Therapies by Sahoo, Biswa Mohan, Banik, Bimal Krishna, Borah, Preetismita, Jain, Adya

“…Reactive Oxygen Species (ROS) refers to the highly reactive substances which contain oxygen radicals. Hypochlorous acid, peroxides, superoxide, singlet oxygen,…”
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Breast Cancer: Current Molecular Therapeutic Targets and New Players by Nagini, Siddavaram

“…Breast cancer is the most common cancer and the most frequent cause of cancer death among women worldwide. Breast cancer is a complex, heterogeneous disease…”
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The Warburg Effect and the Hallmarks of Cancer by Schwartz, Laurent, Supuran, Claudiu T, Alfarouk, Khalid O

“…It is a longstanding debate whether cancer is one disease or a set of very diverse diseases. The goal of this paper is to suggest strongly that most of (if not…”
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A Review of Chemotherapy and Photodynamic Therapy for Lung Cancer Treatment by El-Hussein, Ahmed, Manoto, Sello L, Ombinda-Lemboumba, Saturnin, Alrowaili, Ziyad A, Mthunzi-Kufa, Patience

“…Cancer is among the leading causes of mortality and morbidity worldwide. Among the different types of cancers, lung cancer is considered to be the leading…”
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Molecular Mechanisms of Sanguinarine in Cancer Prevention and Treatment by Ullah, Asmat, Ullah, Najeeb, Nawaz, Touseef, Aziz, Tariq

“…Historically, natural plant-derived drugs received a great impact of consideration in the treatment of several human-associated disorders. Cancer is a…”
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Role of Mitochondrial Membrane Potential and Lactate Dehydrogenase A in Apoptosis by Zaib, Sumera, Hayyat, Aqsa, Ali, Naba, Gul, Asma, Naveed, Muhammad, Khan, Imtiaz

“…Apoptosis is a programmed cell death that occurs due to the production of several catabolic enzymes. During this process, several morphological and biochemical…”
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Recent Developments on 1,2,4-Triazole Nucleus in Anticancer Compounds: A Review by Kaur, Ramandeep, Dwivedi, Ashish Ranjan, Kumar, Bhupinder, Kumar, Vinod

“…1,2,4-triazole is an important nucleus present in a large number of compounds. More than thirty-five compounds containing this nucleus are introduced into the…”
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Ganoderma lucidum Polysaccharides as An Anti-cancer Agent by Sohretoglu, Didem, Huang, Shile

“…The mushroom Ganoderma lucidum (G. lucidum) has been used for centuries in Asian countries to treat various diseases and to promote health and longevity…”
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Plants vs. cancer: a review on natural phytochemicals in preventing and treating cancers and their druggability by Wang, Hu, Khor, Tin Oo, Shu, Limin, Su, Zheng-Yuan, Fuentes, Francisco, Lee, Jong-Hun, Kong, Ah-Ng Tony

“…Cancer remains to be one of the leading causes of death in the United States and around the world. The advent of modern drug-targeted therapies has undeniably…”
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CDK1 in Breast Cancer: Implications for Theranostic Potential by Izadi, Sepideh, Nikkhoo, Afshin, Hojjat-Farsangi, Mohammad, Namdar, Afshin, Azizi, Gholamreza, Mohammadi, Hamed, Yousefi, Mehdi, Jadidi-Niaragh, Farhad

“…Breast cancer has been identified as one of the main cancer-related deaths among women during some last decades. Recent advances in the introduction of novel…”
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Cilengitide: the first anti-angiogenic small molecule drug candidate design, synthesis and clinical evaluation by Mas-Moruno, Carlos, Rechenmacher, Florian, Kessler, Horst

“…Cilengitide, a cyclic RGD pentapeptide, is currently in clinical phase III for treatment of glioblastomas and in phase II for several other tumors. This drug…”
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The role of phenolic compounds in the fight against cancer--a review by Carocho, Márcio, Ferreira, Isabel C F R

“…Cancer is a worldwide scourge; it's the leading cause of death in developed countries and is increasing in developing countries. Mankind has been trying with…”
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Mechanisms of Resistance to Chemotherapy in Gastric Cancer by Marin, J J G, Al-Abdulla, R, Lozano, E, Briz, O, Bujanda, L, Banales, J M, Macias, R I R

“…Although surgical resection is the standard curative therapy for gastric cancer, these tumors are often diagnosed at an advanced stage, when surgery is not…”
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Crocetin and Crocin from Saffron in Cancer Chemotherapy and Chemoprevention by Colapietro, Alessandro, Mancini, Andrea, D'Alessandro, Anna Maria, Festuccia, Claudio

“…Cancer is a disorder which has a powerful impact on the quality life and life expectancy despite the increase in drugs and treatments available for cancer…”
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Molecular Docking Studies and Inhibition Properties of Some Antineoplastic Agents against Paraoxonase-I by Demir, Yeliz, Türkeş, Cüneyt, Beydemir, Şükrü

“…Currently, most of the drugs used in clinical applications show their pharmacological influences by inhibiting or activating enzymes. Therefore, enzyme…”
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Natural Product-Derived Spirooxindole Fragments Serve as Privileged Substructures for Discovery of New Anticancer Agents by Yu, Bin, Zheng, Yi-Chao, Shi, Xiao-Jing, Qi, Ping-Ping, Liu, Hong-Min

“…The utility of natural products for identifying anticancer agents has been highly pursued in the last decades and over 100 drug molecules in clinic are natural…”
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Potential Impacts of Prebiotics and Probiotics on Cancer Prevention by Samanta, Saptadip

“…Cancer is a serious problem throughout the world. The pathophysiology of cancer is multifactorial and is also related to gut microbiota. Intestinal microbes…”
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Copper complexes as anticancer agents by Marzano, Cristina, Pellei, Maura, Tisato, Francesco, Santini, Carlo

“…Metal-based antitumor drugs play a relevant role in antiblastic chemotherapy. Cisplatin is regarded as one of the most effective drugs, even if severe…”
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Molecular Docking Study, Cytotoxicity, Cell Cycle Arrest and Apoptotic Induction of Novel Chalcones Incorporating Thiadiazolyl Isoquinoline in Cervical Cancer by Tantawy, Mohamed A, Sroor, Farid M, Mohamed, Magda F, El-Naggar, Mostafa E, Saleh, Fatma M, Hassaneen, Hamdi M, Abdelhamid, Ismail A

“…Chalcones are naturally occurring compounds found in various plant species which are widely used for the traditional popular treatments. Chalcones are…”
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Resveratrol as an Enhancer of Apoptosis in Cancer: A Mechanistic Review by Ashrafizadeh, Milad, Taeb, Shahram, Haghi-Aminjan, Hamed, Afrashi, Shima, Moloudi, Kave, Musa, Ahmed E, Najafi, Masoud, Farhood, Bagher

“…The resistance to therapy of cancer cells is a challenge for achieving an appropriate therapeutic outcome. Cancer (stem) cells possess several mechanisms for…”
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