Search Results - "Anthony T. Podany"

Plasma and intracellular pharmacokinetics of tenofovir in patients switched from tenofovir disoproxil fumarate to tenofovir alafenamide by Podany, Anthony T, Bares, Sara H, Havens, Joshua, Dyavar, Shetty Ravi, O’Neill, Jennifer, Lee, Sarah, Fletcher, Courtney V, Swindells, Susan, Scarsi, Kimberly K

“…OBJECTIVES:The aim of the study was to compare the intraindividual plasma and intracellular peripheral blood mononuclear cell (PBMC) pharmacokinetics of…”
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ACE-2, TMPRSS2, and Neuropilin-1 Receptor Expression on Human Brain Astrocytes and Pericytes and SARS-CoV-2 Infection Kinetics by Malik, Johid Reza, Acharya, Arpan, Avedissian, Sean N, Byrareddy, Siddappa N, Fletcher, Courtney V, Podany, Anthony T, Dyavar, Shetty Ravi

“…Angiotensin Converting Enzyme 2 (ACE-2), Transmembrane Serine Protease 2 (TMPRSS-2) and Neuropilin-1 cellular receptors support the entry of SARS-CoV-2 into…”
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Transformation of dolutegravir into an ultra-long-acting parenteral prodrug formulation by Deodhar, Suyash, Sillman, Brady, Bade, Aditya N., Avedissian, Sean N., Podany, Anthony T., McMillan, JoEllyn M., Gautam, Nagsen, Hanson, Brandon, Dyavar Shetty, Bhagya L., Szlachetka, Adam, Johnston, Morgan, Thurman, Michellie, Munt, Daniel J., Dash, Alekha K., Markovic, Milica, Dahan, Arik, Alnouti, Yazen, Yazdi, Alborz, Kevadiya, Bhavesh D., Byrareddy, Siddappa N., Cohen, Samuel M., Edagwa, Benson, Gendelman, Howard E.

“…Ultra-long-acting integrase strand transfer inhibitors were created by screening a library of monomeric and dimeric dolutegravir (DTG) prodrug…”
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Role of toll-like receptor 7/8 pathways in regulation of interferon response and inflammatory mediators during SARS-CoV2 infection and potential therapeutic options by Dyavar, Shetty Ravi, Singh, Rahul, Emani, Rohini, Pawar, Ganesh P., Chaudhari, Vinod D., Podany, Anthony T., Avedissian, Sean N., Fletcher, Courtney V., Salunke, Deepak B.

“…Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) is the causative agent of Corona Virus Disease 2019 (COVID-19). Lower production of type I and III…”
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In-vitro and in-vivo assessment of nirmatrelvir penetration into CSF, central nervous system cells, tissues, and peripheral blood mononuclear cells by Avedissian, Sean N., Malik, Johid R., Podany, Anthony T., Neely, Michael, Rhodes, Nathaniel J., Scarsi, Kimberly K., Scheetz, Marc H., Duryee, Michael J., Modebelu, Ukamaka O., Mykris, Timothy M., Winchester, Lee C., Byrareddy, Siddappa N., Fletcher, Courtney V.

“…Three years after SARS-CoV-2 emerged as a global infectious threat, the virus has become endemic. The neurological complications such as depression, anxiety,…”
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Transcriptomic approach predicts a major role for transforming growth factor beta type 1 pathway in L‐Dopa‐induced dyskinesia in parkinsonian rats by Dyavar, Shetty Ravi, Potts, Lisa F., Beck, Goichi, Dyavar Shetty, Bhagya Laxmi, Lawson, Benton, Podany, Anthony T., Fletcher, Courtney V., Amara, Rama Rao, Papa, Stella M.

“…Dyskinesia induced by long‐term L‐Dopa (LID) therapy in Parkinson disease is associated with altered striatal function whose molecular bases remain unclear…”
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Chemotherapy in pediatric brain tumor and the challenge of the blood–brain barrier by Malik, Johid Reza, Podany, Anthony T., Khan, Parvez, Shaffer, Christopher L., Siddiqui, Jawed A., Baranowska‐Kortylewicz, Janina, Le, Jennifer, Fletcher, Courtney V., Ether, Sadia Afruz, Avedissian, Sean N.

“…Background Pediatric brain tumors (PBT) stand as the leading cause of cancer‐related deaths in children. Chemoradiation protocols have improved survival rates,…”
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Diminished Peripheral CD29hi Cytotoxic CD4+ T Cells Are Associated With Deleterious Effects During SIV Infection by Olwenyi, Omalla A, Johnson, Samuel D, Pandey, Kabita, Thurman, Michellie, Acharya, Arpan, Buch, Shilpa J, Fox, Howard S, Podany, Anthony T, Fletcher, Courtney V, Byrareddy, Siddappa N

“…Cytotoxic CD4+ T cells (CD4+ CTLs) limit HIV pathogenesis, as evidenced in elite controllers (a subset of individuals who suppress the virus without the need…”
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Factors associated with viral suppression among cisgender women living with human immunodeficiency virus in the United States: An integrative review by Labisi, Titilola O, Podany, Anthony T, Fadul, Nada A, Coleman, Jason D, King, Keyonna M

“…Introduction: Women account for 23% of new human immunodeficiency virus diagnoses in the United States, yet remain understudied. Adherence to antiretroviral…”
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An Efficient Humanized Mouse Model for Oral Anti-Retroviral Administration by Virdi, Amber K, Ho, Sang, Seaton, Melanie S, Olali, Arnold Z, Narasipura, Srinivas D, Barbian, Hannah J, Olivares, Leannie J, Gonzalez, Hemil, Winchester, Lee C, Podany, Anthony T, Ross, Ryan D, Al-Harthi, Lena, Wallace, Jennillee

“…HIV anti-retrovirals (ARVs) have vastly improved the life expectancy of people living with HIV (PLWH). However, toxic effects attributed to long-term ARV use…”
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Simplifying Rifapentine Dosing for Tuberculosis Treatment and Prevention by Podany, Anthony T

“…Podaby expresses insights about simplifying rifapentine dosing for tuberculosis treatment and prevention. A study by Hibma and colleagues convey results of a…”
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A pharmacist-led medication switch protocol in an academic HIV clinic: patient knowledge and satisfaction by Lee, Sarah S, Havens, Joshua P, Sayles, Harlan R, O'Neill, Jennifer L, Podany, Anthony T, Swindells, Susan, Scarsi, Kimberly K, Bares, Sara H

“…Tenofovir alafenamide (TAF) is associated with less renal and bone toxicity compared with tenofovir disoproxil (TDF). TAF's recent FDA approval has spurred HIV…”
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Current strategies to treat tuberculosis [version 1; peer review: 2 approved] by Podany, Anthony T, Swindells, Susan

“…Tuberculosis (TB) has been a leading cause of death for more than a century. While effective therapies exist, treatment is long and cumbersome. TB control is…”
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Direct Comparison of Chol-siRNA Polyplexes and Chol-DsiRNA Polyplexes Targeting STAT3 in a Syngeneic Murine Model of TNBC by Ye, Zhen, Abdelmoaty, Mai Mohamed, Curran, Stephen M, Dyavar, Shetty Ravi, Kumar, Devendra, Alnouti, Yazen, Coulter, Don W, Podany, Anthony T, Singh, Rakesh K, Vetro, Joseph A

“…RNA interference (RNAi) molecules have tremendous potential for cancer therapy but are limited by insufficient potency after intravenous (IV) administration…”
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In-vitro Immunomodulatory activity of Azadirachta indica A.Juss. Ethanol: water mixture against HIV associated chronic CD4 + T-cell activation/ exhaustion by Olwenyi, Omalla A, Asingura, Bannet, Naluyima, Prossy, Anywar, Godwin Upoki, Nalunga, Justine, Nakabuye, Mariam, Semwogerere, Michael, Bagaya, Bernard, Cham, Fatim, Tindikahwa, Allan, Kiweewa, Francis, Lichter, Eliezer Z, Podany, Anthony T, Fletcher, Courtney V, Byrareddy, Siddappa N, Kibuuka, Hannah

“…In Sub-Saharan Africa, herbal therapy continues to be utilized for HIV-1 disease management. However, the therapeutic benefits of these substances remain…”
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HIV-1 Integrase Inhibitors: A Comparative Review of Efficacy and Safety by Scarsi, Kimberly K., Havens, Joshua P., Podany, Anthony T., Avedissian, Sean N., Fletcher, Courtney V.

“…The newest class of antiretrovirals for all persons living with HIV are the integrase strand transfer inhibitors (INSTIs). Since 2007, five INSTIs have been…”
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Comparative Clinical Pharmacokinetics and Pharmacodynamics of HIV-1 Integrase Strand Transfer Inhibitors by Podany, Anthony T., Scarsi, Kimberly K., Fletcher, Courtney V.

“…Dolutegravir (DTG), elvitegravir (EVG) and raltegravir (RAL) are members of the latest class of antiretrovirals (ARVs) that have become available to treat…”
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Comparative Clinical Pharmacokinetics and Pharmacodynamics of HIV-1 Integrase Strand Transfer Inhibitors: An Updated Review by Podany, Anthony T., Scarsi, Kimberly K., Pham, Michelle M., Fletcher, Courtney V.

“…Bictegravir, cabotegravir, dolutegravir, elvitegravir, and raltegravir are members of the latest class of antiretrovirals available to treat human…”
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Cross-validation of a high-performance liquid chromatography nevirapine plasma assay in a resource-limited setting in Zimbabwe by Makita-Chingombe, Faithful, Podany, Anthony T., Mykris, Timothy, Muzambi, Farai, Browne, Richard W., Ocque, Andrew J., DiFrancesco, Robin, Winchester, Lee C., Fletcher, Courtney V., Mudzviti, Tinashe, Maponga, Charles C., Morse, Gene D.

“…An international HIV pharmacology specialty laboratory (PSL) was established at the University of Zimbabwe to increase bioanalytical and investigator…”
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Clinical Pharmacokinetics and Pharmacodynamics of Etravirine: An Updated Review by Havens, Joshua P., Podany, Anthony T., Scarsi, Kimberly K., Fletcher, Courtney V.

“…Etravirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) for the treatment of human immunodeficiency virus type 1 infection. It…”
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