Search Results - "Anthony J. Celeste"

Synergistic Roles of Bone Morphogenetic Protein 15 and Growth Differentiation Factor 9 in Ovarian Function by Yan, Changning, Wang, Pei, DeMayo, Janet, DeMayo, Francesco J, Elvin, Julia A, Carino, Cecilia, Prasad, Sarvamangala V, Skinner, Sheri S, Dunbar, Bonnie S, Dube, Jennifer L, Celeste, Anthony J, Matzuk, Martin M

“…Knockout mouse technology has been used over the last decade to define the essential roles of ovarian-expressed genes and uncover genetic interactions. In…”
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The Bone Morphogenetic Protein 15 Gene Is X-Linked and Expressed in Oocytes by Dube, Jennifer L, Wang, Pei, Elvin, Julia, Lyons, Karen M, Celeste, Anthony J, Matzuk, Martin M

“…We have taken advantage of the sequence relationships among the bone morphogenetic proteins (BMPs) to identify the mouse Bmp15 and human BMP15 genes. The…”
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Bone morphogenetic proteins and growth differentiation factors as drug targets in cardiovascular and metabolic disease by Tobin, James F., Celeste, Anthony J.

“…Bone morphogenetic proteins (BMPs) and growth differentiation factors (GDFs) control the development and homeostasis of multiple tissue types in many…”
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Novel Regulators of Bone Formation: Molecular Clones and Activities by Wozney, John M., Rosen, Vicki, Celeste, Anthony J., Mitsock, Lisa M., Whitters, Matthew J., Kriz, Ronald W., Hewick, Rodney M., Wang, Elizabeth A.

“…Protein extracts derived from bone can initiate the process that begins with cartilage formation and ends in de novo bone formation. The critical components of…”
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Engineering of a GLP-1 analogue peptide/anti-PCSK9 antibody fusion for type 2 diabetes treatment by Chodorge, Matthieu, Celeste, Anthony J., Grimsby, Joseph, Konkar, Anish, Davidsson, Pia, Fairman, David, Jenkinson, Lesley, Naylor, Jacqueline, White, Nicholas, Seaman, Jonathan C., Dickson, Karen, Kemp, Benjamin, Spooner, Jennifer, Rossy, Emmanuel, Hornigold, David C., Trevaskis, James L., Bond, Nicholas J., London, Timothy B., Buchanan, Andrew, Vaughan, Tristan, Rondinone, Cristina M., Osbourn, Jane K.

“…Type 2 diabetes (T2D) is a complex and progressive disease requiring polypharmacy to manage hyperglycaemia and cardiovascular risk factors. However, most…”
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Myostatin, a negative regulator of muscle mass: implications for muscle degenerative diseases by Tobin, James F, Celeste, Anthony J

“…Myostatin is a secreted protein that negatively regulates skeletal muscle mass determining both muscle fiber number and size. The myostatin pathway is…”
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Ectopic induction of tendon and ligament in rats by growth and differentiation factors 5, 6, and 7, members of the TGF-beta gene family by Wolfman, N M, Hattersley, G, Cox, K, Celeste, A J, Nelson, R, Yamaji, N, Dube, J L, DiBlasio-Smith, E, Nove, J, Song, J J, Wozney, J M, Rosen, V

“…Little is known about the regulatory signals involved in tendon and ligament formation, and this lack of understanding has hindered attempts to develop…”
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Bone morphogenetic proteins and growth differentialtion factors as drug targets in cardiovascular and metabolic disease by TOBIN, James F, CELESTE, Anthony J

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Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo by Graff, J M, Thies, R S, Song, J J, Celeste, A J, Melton, D A

“…We report the isolation of a Xenopus BMP receptor that is expressed maternally in the appropriate location to play a role in mesoderm induction. This receptor…”
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A novel BMP expressed in developing mouse limb, spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos by Gamer, L W, Wolfman, N M, Celeste, A J, Hattersley, G, Hewick, R, Rosen, V

“…The bone morphogenetic proteins (BMPs) play critical roles in patterning the early embryo and in the development of many organs and tissues. We have identified…”
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Nodal Signaling Uses Activin and Transforming Growth Factor-β Receptor-regulated Smads by Kumar, Amit, Novoselov, Vladimir, Celeste, Anthony J., Wolfman, Neil M., ten Dijke, Peter, Kuehn, Michael R.

“…Nodal, a member of the transforming growth factor β (TGF-β) superfamily, is implicated in many events critical to the early vertebrate embryo, including…”
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Identification of Transforming Growth Factor β Family Members Present in Bone-Inductive Protein Purified from Bovine Bone by Celeste, Anthony J., Iannazzi, James A., Taylor, Robin C., Hewick, Rodney M., Rosen, Vicki, Wang, Elizabeth A., Wozney, John M.

“…Characterization of the polypeptides present in bone-inductive protein extracts from bovine bone has led to the cloning of seven regulatory molecules, six of…”
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Bone morphogenetic protein-9 binds to liver cells and stimulates proliferation by Song, J J, Celeste, A J, Kong, F M, Jirtle, R L, Rosen, V, Thies, R S

“…A new member of the transforming growth factor (TGF)-beta superfamily, BMP-9, has recently been identified and shown to be expressed in the developing mouse…”
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Nodal Signaling Uses Activin and Transforming Growth Factor-β Receptor-regulated Smads by Amit Kumar, Vladimir Novoselov, Anthony J. Celeste, Neil M. Wolfman, Peter ten Dijke, Michael R. Kuehn

“…Nodal, a member of the transforming growth factor β (TGF-β) superfamily, is implicated in many events critical to the early vertebrate embryo, including…”
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A mammalian serine/threonine kinase receptor specifically binds BMP-2 and BMP-4 by Yamaji, N, Celeste, A J, Thies, R S, Song, J J, Bernier, S M, Goltzman, D, Lyons, K M, Nove, J, Rosen, V, Wozney, J M

“…Bone morphogenetic proteins (BMPs) are a class of related growth and differentiation factors within the TGF-beta superfamily of proteins which are known to…”
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Isolation of zebrafish gdf7 and comparative genetic mapping of genes belonging to the growth/differentiation factor 5, 6, 7 subgroup of the TGF-beta superfamily by Davidson, A J, Postlethwait, J H, Yan, Y L, Beier, D R, van Doren, C, Foernzler, D, Celeste, A J, Crosier, K E, Crosier, P S

“…The Growth/differentiation factor (Gdf) 5, 6, 7 genes form a closely related subgroup belonging to the TGF-beta superfamily. In zebrafish, there are three…”
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A Novel BMP Expressed in Developing Mouse Limb, Spinal Cord, and Tail Bud Is a Potent Mesoderm Inducer inXenopusEmbryos by Gamer, Laura W., Wolfman, Neil M., Celeste, Anthony J., Hattersley, Gary, Hewick, Rod, Rosen, Vicki

“…The bone morphogenetic proteins (BMPs) play critical roles in patterning the early embryo and in the development of many organs and tissues. We have identified…”
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Novel Regulators of Bone Formation: Molecular Clones and Activites by Wozney, John M, Rosen, Vicki, Celeste, Anthony J, Mitsock, Lisa M, Whitters, Matthew J

“…Human complementary DNA clones responding to three polypeptides present in bone morphogenetic protein (BMP) have been isolated, and expression of the…”
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