Search Results - "Antao, Olivia Q."

H1N1 influenza virus infection results in adverse pregnancy outcomes by disrupting tissue-specific hormonal regulation by Littauer, Elizabeth Q, Esser, E Stein, Antao, Olivia Q, Vassilieva, Elena V, Compans, Richard W, Skountzou, Ioanna

“…Increased susceptibility to influenza virus infection during pregnancy has been attributed to immunological changes occurring before and during gestation in…”
Get full text

Aberrant zonal recycling of germinal center B cells impairs appropriate selection in lupus by Sanchez, Gina M., Hirsch, Eden S., VanValkenburg, Arthur, Mayer, Daniel P., Gbedande, Komi, Francis, Rebecca L., Song, Wenzhi, Antao, Olivia Q., Brimmer, Kyleigh E., Lemenze, Alexander, Stephens, Robin, Johnson, W. Evan, Weinstein, Jason S.

“…Autoimmune diseases such as lupus are characterized by polyclonal B cell activation, leading to the production of autoantibodies. The mechanism leading to B…”
Get full text

Pregnancy Downregulates Plasmablast Metabolic Gene Expression Following Influenza Without Altering Long-Term Antibody Function by Swieboda, Dominika, Littauer, Elizabeth Q, Beaver, Jacob T, Mills, Lisa K, Bricker, Katherine M, Esser, E Stein, Antao, Olivia Q, Williams, Dahnide T, Skountzou, Ioanna

“…While the majority of influenza-infected individuals show no or mild symptomatology, pregnant women are at higher risk of complications and…”
Get full text

Improved Humoral Immunity and Protection against Influenza Virus Infection with a 3d Porous Biomaterial Vaccine by Miwa, Hiromi, Antao, Olivia Q, Kelly-Scumpia, Kindra M, Baghdasarian, Sevana, Mayer, Daniel P, Shang, Lily, Sanchez, Gina M, Archang, Maani M, Scumpia, Philip O, Weinstein, Jason S, Di Carlo, Dino

“…New vaccine platforms that activate humoral immunity and generate neutralizing antibodies are required to combat emerging pathogens, including influenza virus…”
Get full text

Zika virus-induced neuro-ocular pathology in immunocompetent mice correlates with anti-ganglioside autoantibodies by Beaver, Jacob T., Mills, Lisa K., Swieboda, Dominika, Lelutiu, Nadia, Esser, Edward S., Antao, Olivia Q., Scountzou, Eugenia, Williams, Dahnide T., Papaioannou, Nikolaos, Littauer, Elizabeth Q., Skountzou, Ioanna

“…A severe consequence of adult Zika virus (ZIKV) infection is Guillain-Barré Syndrome (GBS), where autoreactive antibodies attack peripheral and central nervous…”
Get full text

Cutaneous vaccination ameliorates Zika virus-induced neuro-ocular pathology via reduction of anti-ganglioside antibodies by Beaver, Jacob T., Mills, Lisa K., Swieboda, Dominika, Lelutiu, Nadia, Esser, Edward S., Antao, Olivia Q., Scountzou, Eugenia, Williams, Dahnide T., Papaioannou, Nikolaos, Littauer, Elizabeth Q., Romanyuk, Andrey, Compans, Richard W., Prausnitz, Mark R., Skountzou, Ioanna

“…Zika virus (ZIKV) causes moderate to severe neuro-ocular sequelae, with symptoms ranging from conjunctivitis to Guillain-Barré Syndrome (GBS). Despite the…”
Get full text

Development of Tbet- and CD11c-expressing B cells in a viral infection requires T follicular helper cells outside of germinal centers by Song, Wenzhi, Antao, Olivia Q., Condiff, Emily, Sanchez, Gina M., Chernova, Irene, Zembrzuski, Krzysztof, Steach, Holly, Rubtsova, Kira, Angeletti, Davide, Lemenze, Alexander, Laidlaw, Brian J., Craft, Joe, Weinstein, Jason S.

“…Tbet+CD11c+ B cells arise during type 1 pathogen challenge, aging, and autoimmunity in mice and humans. Here, we examined the developmental requirements of…”
Get full text

Type I Interferon–Activated STAT4 Regulation of Follicular Helper T Cell–Dependent Cytokine and Immunoglobulin Production in Lupus by Dong, Xuemei, Antao, Olivia Q., Song, Wenzhi, Sanchez, Gina M., Zembrzuski, Krzysztof, Koumpouras, Fotios, Lemenze, Alexander, Craft, Joe, Weinstein, Jason S.

“…Objective To assess the role of STAT4 activation in driving pathogenic follicular helper T (Tfh) cell secretion of the cytokines interleukin‐21 (IL‐21) and…”
Get full text

A novel microporous biomaterial vaccine platform for long-lasting antibody mediated immunity against viral infection by Mayer, Daniel P., Nelson, Mariah E., Andriyanova, Daria, Filler, Renata B., Ökten, Arya, Antao, Olivia Q., Chen, Jennifer S., Scumpia, Philip O., Weaver, Westbrook M., Wilen, Craig B., Deshayes, Stephanie, Weinstein, Jason S.

“…Current antigen delivery platforms, such as alum and nanoparticles, are not readily tunable, thus may not generate optimal adaptive immune responses. We…”
Get full text

A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies by Wu, Jiaxi, Bloch, Nicolin, Chang, Aaron Y., Bhavsar, Ramandeep, Wang, Qingqing, Crawford, Alison, DiLillo, David J., Vazzana, Kristin, Mohrs, Katja, Dudgeon, Drew, Patel, Supriya, Ahmed, Hassan, Garg, Vidur, Amatulli, Michael, Antao, Olivia Q., Yan, Yuetian, Wang, Shunhai, Ramos, Willy, Krueger, Pamela, Adler, Christina, Ni, Min, Wei, Yi, Guo, Chunguang, Macdonald, Lynn, Huang, Tammy, Ullman, Erica, Hermann, Aynur, Yancopoulos, George D., Murphy, Andrew J., Davis, Samuel, Olson, William C., Lin, John C., Smith, Eric, Zhang, Tong

“…The clinical use of interleukin-2 (IL-2) for cancer immunotherapy is limited by severe toxicity. Emerging IL-2 therapies with reduced IL-2 receptor alpha…”
Get full text

Type 1 interferon activated STAT4 regulates T follicular helper (Tfh)-cell dependent cytokine and immunoglobulin production in lupus by Dong, Xuemei, Antao, Olivia Q., Song, Wenzhi, Sanchez, Gina M., Zembrzuski, Krzysztof, Koumpouras, Fotios, Lemenze, Alexander, Craft, Joe, Weinstein, Jason S.

Get full text

Systemic dysregulation of cellular immune responses to H1N1 infection during pregnancy by Littauer, Elizabeth Q, Esser, E. Stein, Antao, Olivia Q, Williams, Dahnide T, Compans, Richard W, Skountzou, Ioanna

“…Abstract The 2009 H1N1 flu pandemic demonstrated that pregnant women infected with influenza were at risk for severe respiratory distress and…”
Get full text